What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Cyclin E, Cell biology, Ubiquitin ligase, Cyclin-dependent kinase and Cyclin A2.
His Molecular biology research extends to Cell biology, which is thematically connected.
His study in the fields of F-box protein under the domain of Ubiquitin ligase overlaps with other disciplines such as Amyloid precursor protein secretase.
His F-box protein research incorporates themes from Carcinogenesis and Cell growth.
Bruce E. Clurman has researched Cyclin-dependent kinase in several fields, including Caspase 2, Kinase and Cyclin-dependent kinase 2.
His Cyclin A2 research includes elements of Cyclin B, Cyclin A and Cyclin D.
His most cited work include:
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease (990 citations)
- Cyclin E-CDK2 is a regulator of p27Kip1. (842 citations)
- FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. (801 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cell biology, Cancer research, Cyclin E, Ubiquitin ligase and Cyclin-dependent kinase.
Bruce E. Clurman interconnects Molecular biology, Ubiquitin, F-box protein and Biochemistry in the investigation of issues within Cell biology.
His Cancer research study incorporates themes from Carcinogenesis, Cell cycle, Gene, Stem cell and Wee1.
The various areas that Bruce E. Clurman examines in his Cyclin E study include Genome instability, Cyclin A, Cell growth and Kinase activity.
His Cyclin A research is multidisciplinary, incorporating perspectives in Cyclin A2 and Cyclin D.
His study focuses on the intersection of Ubiquitin ligase and fields such as Protein degradation with connections in the field of Degron.
He most often published in these fields:
- Cell biology (66.67%)
- Cancer research (41.44%)
- Cyclin E (52.25%)
What were the highlights of his more recent work (between 2014-2021)?
- Cancer research (41.44%)
- Wee1 (6.31%)
- Cell cycle (20.72%)
In recent papers he was focusing on the following fields of study:
Bruce E. Clurman spends much of his time researching Cancer research, Wee1, Cell cycle, Ubiquitin ligase and DNA damage.
His Cancer research study integrates concerns from other disciplines, such as Insertional mutagenesis, Transposase, Carcinogenesis, Gene and Cyclin.
His work deals with themes such as Cancer cell and T cell, which intersect with Cell cycle.
His Ubiquitin ligase research includes themes of Small hairpin RNA, Colorectal cancer, Metabolic reprogramming and Cell biology.
His biological study spans a wide range of topics, including Embryonic stem cell, Germ line development, Cell growth, Binding site and Consensus site.
Bruce E. Clurman has included themes like Cyclin-dependent kinase 1, Cyclin E and Programmed cell death in his Cyclin-dependent kinase study.
Between 2014 and 2021, his most popular works were:
- Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. (84 citations)
- DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing (17 citations)
- RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions (14 citations)
In his most recent research, the most cited papers focused on:
Bruce E. Clurman mainly focuses on Cancer research, Carcinogenesis, Ubiquitin, DNA and DNA repair.
He interconnects Insertional mutagenesis, Transposase, Sleeping Beauty transposon system, Mitochondrion and Cyclin in the investigation of issues within Cancer research.
Bruce E. Clurman has researched Carcinogenesis in several fields, including HEK 293 cells, Viral replication and Antigen.
His research on Ubiquitin focuses in particular on Ubiquitin ligase.
His DNA research integrates issues from Drosha, Cell biology, Binding site and Consensus site.
His study in DNA repair is interdisciplinary in nature, drawing from both Molecular biology, microRNA and DNA damage.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
