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D-Index & Metrics

Molecular Biology

D-Index
59
Citations
13732
World Ranking
2014
National Ranking
1001

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Marc S. Wold is affiliated with the University of Iowa in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Cellular and Molecular Neuroscience, Physiology, Cardiology and Cardiovascular Medicine, and Genetics.

Their work addresses several scientific topics, including DNA Repair Mechanisms, Mitochondrial Function and Pathology, Genetic Neurodegenerative Diseases, Telomeres, Telomerase, and Senescence, CRISPR and Genetic Engineering, Epigenetics and DNA Methylation, and Cardiomyopathy and Myosin Studies.

Recent published papers by Marc S. Wold include:

  • "A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo" (2020, Nature Genetics)
  • "Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue" (2021, Blood)
  • "WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage" (2022, Nature Communications)
  • "Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability" (2023, Cell)
  • "Antagonistic roles of canonical and alternative RPA in tandem CAG repeat diseases" (2022, bioRxiv (Cold Spring Harbor Laboratory))

Marc S. Wold has frequently published in the following venues:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Genetics
  • Nature Communications
  • Cell

Frequent co-authors collaborating with Marc S. Wold include:

  • Gagan B. Panigrahi
  • Stella Lanni
  • Terence Gall-Duncan
  • Jennifer Luo
  • Marie-Christine Caron

Marc S. Wold was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism

    Marc S. Wold

  • Recombinant replication protein A: expression, complex formation, and functional characterization.

    Leigh A. Henricksen;Christopher B. Umbricht;Marc S. Wold

  • Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA.

    Marc S. Wold;Thomas Kelly

  • RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

    Zhigang He;L. A. Henricksen;M. S. Wold;C. J. Ingles

  • Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro.

    Liu Yang;Marc S. Wold;Joachim J. Li;Thomas J. Kelly

  • Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.

    Rong‐Guang Shao;Chun‐Xia Cao;Hongliang Zhang;Kurt W. Kohn

  • Binding properties of replication protein A from human and yeast cells.

    Changsoo Kim;R. O. Snyder;M. S. Wold

  • Replication Protein A phosphorylation and the cellular response to DNA damage

    Sara K. Binz;Anne M. Sheehan;Marc S. Wold

  • Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template

    Marc S. Wold;Joachim J. Li;Thomas J. Kelly

  • Interactions of human replication protein A with oligonucleotides

    Changsoo Kim;Brian F. Paulus;Marc S. Wold

  • Replication protein A: single-stranded DNA's first responder: dynamic DNA-interactions allow replication protein A to direct single-strand DNA intermediates into different pathways for synthesis or repair.

    Ran Chen;Marc S. Wold

  • Identification of cellular proteins required for simian virus 40 DNA replication.

    M S Wold;D H Weinberg;D M Virshup;J J Li

  • Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions

    Jerzy Majka;Sara K. Binz;Marc S. Wold;Peter M.J. Burgers

  • Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA.

    Efim I. Golub;Ravindra C. Gupta;Thomas Haaf;Marc S. Wold

  • Role of protein-protein interactions in the function of replication protein A (RPA): RPA modulates the activity of DNA polymerase alpha by multiple mechanisms.

    Braun Ka;Lao Y;He Z;Ingles Cj

  • Replication protein A (RPA) phosphorylation prevents RPA association with replication centers.

    Vitaly M. Vassin;Marc S. Wold;James A. Borowiec

  • Reconstitution of simian virus 40 DNA replication with purified proteins.

    David H. Weinberg;Kathleen L. Collins;Pamela Simancek;Alicia Russo

  • Inhibition of homologous recombination by DNA-dependent protein kinase requires kinase activity, is titratable, and is modulated by autophosphorylation.

    Jessica A. Neal;Van Dang;Pauline Douglas;Marc S. Wold

  • Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.

    Jun Hyuk Choi;Laura A. Lindsey-Boltz;Michael Kemp;Aaron C. Mason

  • Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase.

    Doug W. Chan;Seong-Cheol Son;Wesley Block;Ruiqiong Ye

Frequent Co-Authors

Thomas J. Kelly
Thomas J. Kelly Memorial Sloan Kettering Cancer Center
Aziz Sancar
Aziz Sancar University of North Carolina at Chapel Hill
Robert M. Brosh
Robert M. Brosh National Institutes of Health
Olga I. Lavrik
Olga I. Lavrik Russian Academy of Sciences
David M. Virshup
David M. Virshup Duke NUS Graduate Medical School
Susan P. Lees-Miller
Susan P. Lees-Miller University of Calgary
Zhigang He
Zhigang He Boston Children's Hospital
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Guo Min Li
Guo Min Li The University of Texas Southwestern Medical Center
Christopher E. Pearson
Christopher E. Pearson University of Toronto

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