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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
14900
World Ranking
10177
National Ranking
106

Overview

Claus Oxvig is affiliated with Aarhus University in Denmark and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their scholarly activities span multiple specialized subfields, including molecular biology, endocrinology, diabetes and metabolism, physiology, genetics, and cell biology.

Their research primarily focuses on growth hormone and insulin-like growth factors, with additional interests in zebrafish biomedical research applications, phagocytosis and immune regulation, pancreatic function and diabetes, extracellular vesicles in disease, physiological and biochemical adaptations, and reproductive biology and fertility.

Frequent publication venues for Claus Oxvig include The Journal of Clinical Endocrinology & Metabolism, bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, ACS Nano, and Endocrine Reviews. They have published several papers in these journals, reflecting ongoing contributions to scientific literature.

Recent papers authored or coauthored by Claus Oxvig include:

  • The Stanniocalcin-PAPP-A-IGFBP-IGF Axis, 2023, The Journal of Clinical Endocrinology & Metabolism
  • Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution, 2020, ACS Nano
  • Pappalysins and Stanniocalcins and Their Relationship With the Peripheral IGF Axis in Newborns and During Development, 2022, The Journal of Clinical Endocrinology & Metabolism
  • The Pregnancy-Associated Plasma Protein-A (PAPP-A) Story, 2023, Endocrine Reviews
  • Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism, 2022, Nature Communications

Among frequent coauthors in Claus Oxvig's work are Kasper Kjær-Sørensen, Cheryl A. Conover, Pernille Rimmer Noer, Yuya Hayashi, and Thomas Boesen, indicating collaborative efforts across several projects and publications.

Best Publications

  • Pregnancy-Associated Plasma Protein A as a Marker of Acute Coronary Syndromes

    Antoni Bayes-Genis;Cheryl A. Conover;Michael T. Overgaard;Kent R. Bailey

  • The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

    James B. Lawrence;Claus Oxvig;Michael T. Overgaard;Lars Sottrup-Jensen

  • The structural basis of calcium transport by the calcium pump

    Claus Olesen;Martin Picard;Martin Picard;Anne-Marie Lund Winther;Anne-Marie Lund Winther;Claus Gyrup

  • Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A.

    Lisbeth S. Laursen;Michael T. Overgaard;Rikke Søe;Henning B. Boldt

  • Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development

    Cheryl A. Conover;Laurie K. Bale;Michael T. Overgaard;Edward W. Johnstone

  • Pregnancy-associated Plasma Protein-A2 (PAPP-A2), a Novel Insulin-like Growth Factor-binding Protein-5 Proteinase

    Michael T. Overgaard;Henning B. Boldt;Lisbeth S. Laursen;Lars Sottrup-Jensen

  • Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein.

    C Oxvig;O Sand;T Kristensen;G J Gleich

  • Expression of Recombinant Human Pregnancy-Associated Plasma Protein-A and Identification of the Proform of Eosinophil Major Basic Protein as its Physiological Inhibitor*

    Michael T. Overgaard;Jesper Haaning;Henning B. Boldt;Inger M. Olsen

  • Insulin-Like Growth Factor Binding Protein-4 Protease Produced by Smooth Muscle Cells Increases in the Coronary Artery After Angioplasty

    Antoni Bayes-Genis;Robert S. Schwartz;Debra A. Lewis;Michael T. Overgaard

  • Rare and low-frequency coding variants alter human adult height

    Eirini Marouli;Mariaelisa Graff;Carolina Medina-Gomez;Ken Sin Lo

  • The role of PAPP-A in the IGF system: location, location, location

    Claus Oxvig

  • Conformational changes in tertiary structure near the ligand binding site of an integrin I domain

    Claus Oxvig;Chafen Lu;Timothy A. Springer

  • Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.

    Henning Bünsow Boldt;Michael Toft Overgaard;L S Laursen;Kathrin Weyer

  • Pregnancy-Associated Plasma Protein-A Is Involved in Insulin-Like Growth Factor Binding Protein-2 (IGFBP-2) Proteolytic Degradation in Bovine and Porcine Preovulatory Follicles: Identification of Cleavage Site and Characterization of IGFBP-2 Degradation

    Philippe Monget;Sabine Mazerbourg;Thierry Delpuech;Marie-Christine Maurel

  • Severe Preeclampsia-Related Changes in Gene Expression at the Maternal-Fetal Interface Include Sialic Acid-Binding Immunoglobulin-Like Lectin-6 and Pappalysin-2

    Virginia D. Winn;Matthew Gormley;Agnes C. Paquet;Kasper Kjær-Sørensen

  • Regulation of human ADAM 12 protease by the prodomain. Evidence for a functional cysteine switch.

    Frosty Loechel;Michael T. Overgaard;Claus Oxvig;Reidar Albrechtsen

  • Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ovine, Bovine, Porcine, and Equine Ovarian Follicles: Involvement in IGF Binding Protein-4 Proteolytic Degradation and mRNA Expression During Follicular Development

    Sabine Mazerbourg;Michael T. Overgaard;Claus Oxvig;Michael Christiansen

  • Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability

    Andrew Dauber;María T Muñoz‐Calvo;Vicente Barrios;Horacio M Domené

  • An isolated, surface-expressed I domain of the integrin αLβ2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond

    Chafen Lu;Motomu Shimaoka;Mazen Ferzly;Claus Oxvig

  • The structural basis of calcium transport by the calcium pump

    C. Olesen;M. Picard;A.-M.L. Winther;C.G. Nielsen

Frequent Co-Authors

Michael Toft Overgaard
Michael Toft Overgaard Aalborg University
Lars Sottrup-Jensen
Lars Sottrup-Jensen Aarhus University
Jan Frystyk
Jan Frystyk Odense University Hospital
Michael Christiansen
Michael Christiansen Statens Serum Institut
Linda C. Giudice
Linda C. Giudice University of California, San Francisco
Gerald J. Gleich
Gerald J. Gleich University of Utah
Claus Yding Andersen
Claus Yding Andersen Copenhagen University Hospital
Cunming Duan
Cunming Duan University of Michigan–Ann Arbor
Jan J. Enghild
Jan J. Enghild Aarhus University

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