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Edward B. Lee

D-Index & Metrics

Medicine

D-Index
78
Citations
34399
World Ranking
17817
National Ranking
8889

Edward B. Lee publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Edward B. Lee sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 610 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 264 publications — 10th percentile

10% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Edward B. Lee D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Edward B. Lee sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 399 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 78 D-Index — 12th percentile

12% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Edward B. Lee is affiliated with the University of Pennsylvania in the United States. Their research primarily focuses on medicine, with a specialized emphasis on neurology, physiology, molecular biology, psychiatry and mental health, as well as radiology, nuclear medicine, and imaging.

The scientist's work covers a range of topics including:

  • Alzheimer's disease research and treatments
  • Parkinson's Disease mechanisms and treatments
  • Dementia and cognitive impairment research
  • Amyotrophic lateral sclerosis research
  • Advanced neuroimaging techniques and applications
  • Neurological diseases and metabolism
  • Neuroinflammation and neurodegeneration mechanisms

Edward B. Lee has contributed extensively to the academic literature with notable recent papers such as:

  • Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation (2020, Nature Medicine)
  • SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network (2021, Nature Methods)
  • TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A (2022, Nature)
  • Distribution patterns of tau pathology in progressive supranuclear palsy (2020, Acta Neuropathologica)
  • APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease (2020, Acta Neuropathologica)

The frequent co-authors collaborating with Edward B. Lee include:

  • David J. Irwin
  • John Q. Trojanowski
  • David A. Wolk
  • Corey T. McMillan
  • Murray Grossman

The scientist's publications are commonly found in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Neuropathologica
  • Alzheimer's & Dementia
  • Brain
  • Acta Neuropathologica Communications

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis

    Johannes Brettschneider;Kelly Del Tredici;Jon B. Toledo;John L. Robinson

  • Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

    Erik C.B. Johnson;Eric B. Dammer;Duc M. Duong;Lingyan Ping

  • Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

    John L Robinson;Edward B Lee;Sharon X Xie;Lior Rennert

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration

    Edward B. Lee;Virginia M.-Y. Lee;John Q. Trojanowski

  • Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

    Manuela Neumann;Manuela Neumann;Linda K. Kwong;Edward B. Lee;Elisabeth Kremmer

  • Neuropathological and Genetic Correlates of Survival and Dementia Onset in Synucleinopathies: A Retrospective Analysis

    David J Irwin;Murray Grossman;Daniel Weintraub;Daniel Weintraub;Howard I Hurtig

  • SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network.

    Jian Hu;Xiangjie Li;Kyle Coleman;Amelia Schroeder

  • Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

    Gabor G. Kovacs;Isidro Ferrer;Lea T. Grinberg;Lea T. Grinberg;Irina Alafuzoff

  • Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

    Bin Zhang;Arpita Maiti;Sharon Shively;Fara Lakhani

  • Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

    Lionel M. Igaz;Linda K. Kwong;Edward B. Lee;Alice Chen-Plotkin

  • Targeting Amyloid-β Peptide (Aβ) Oligomers by Passive Immunization with a Conformation-selective Monoclonal Antibody Improves Learning and Memory in Aβ Precursor Protein (APP) Transgenic Mice

    Edward B. Lee;Lewis Z. Leng;Bin Zhang;Linda Kwong

  • Distribution patterns of tau pathology in progressive supranuclear palsy

    Gabor G. Kovacs;Gabor G. Kovacs;Gabor G. Kovacs;Milica Jecmenica Lukic;Milica Jecmenica Lukic;David J. Irwin;Thomas Arzberger

  • Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias

    Mark Yarchoan;Sharon X. Xie;Mitchel A. Kling;Mitchel A. Kling;Jon B. Toledo

  • C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD.

    Jacqueline G O'Rourke;Laurent P Bogdanik;A K M G Muhammad;Tania F Gendron

  • TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

    Johannes Brettschneider;Kimihito Arai;Kelly Del Tredici;Jon B. Toledo

  • Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine

    David J. Irwin;Nigel J. Cairns;Murray Grossman;Corey T. McMillan

  • Axonal Transport, Amyloid Precursor Protein, Kinesin-1, and the Processing Apparatus: Revisited

    Orly Lazarov;Gerardo A. Morfini;Edward B. Lee;Mohamed H. Farah

  • Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi

Frequent Co-Authors

John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
David J. Irwin
David J. Irwin University of Pennsylvania
Murray Grossman
Murray Grossman University of Pennsylvania
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
Vivianna M. Van Deerlin
Vivianna M. Van Deerlin University of Pennsylvania
Corey T. McMillan
Corey T. McMillan University of Pennsylvania
David A. Wolk
David A. Wolk University of Pennsylvania
Sharon X. Xie
Sharon X. Xie University of Pennsylvania
Gabor G. Kovacs
Gabor G. Kovacs University of Toronto
Jon B. Toledo
Jon B. Toledo Houston Methodist

External Links

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Best Scientists Citing Edward B. Lee

John Q. Trojanowski

John Q. Trojanowski

University of Pennsylvania

Publications: 199

Virginia M.-Y. Lee

Virginia M.-Y. Lee

University of Pennsylvania

Publications: 159

Dennis W. Dickson

Dennis W. Dickson

Mayo Clinic

Publications: 110

Albert C. Ludolph

Albert C. Ludolph

University of Ulm

Publications: 90

Glenda M. Halliday

Glenda M. Halliday

University of Sydney

Publications: 78

Murray Grossman

Murray Grossman

University of Pennsylvania

Publications: 72

Rosa Rademakers

Rosa Rademakers

University of Antwerp

Publications: 66

James B. Rowe

James B. Rowe

University of Cambridge

Publications: 64

David J. Irwin

David J. Irwin

University of Pennsylvania

Publications: 63

Kaj Blennow

Kaj Blennow

University of Gothenburg

Publications: 62

Leonard Petrucelli

Leonard Petrucelli

Mayo Clinic

Publications: 61

Gabor G. Kovacs

Gabor G. Kovacs

University of Toronto

Publications: 59

Henrik Zetterberg

Henrik Zetterberg

University of Gothenburg

Publications: 58

Jan Kassubek

Jan Kassubek

University of Ulm

Publications: 56

John R. Hodges

John R. Hodges

University of Sydney

Publications: 54

Julie A. Schneider

Julie A. Schneider

Rush University Medical Center

Publications: 51

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