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Biology and Biochemistry

D-Index
66
Citations
15826
World Ranking
8657
National Ranking
3885

Overview

Samuel A. Santoro is affiliated with Vanderbilt University in the United States and is active in the field of medicine. Their research primarily addresses topics related to wound healing and treatments, signaling pathways in disease, and cell adhesion molecules research. The focus on these areas reflects an interdisciplinary approach that combines aspects of rehabilitation, molecular biology, and immunology and allergy.

Santoro's recent publications demonstrate engagement with both clinical and molecular research domains. One of their works, published in 2021, titled "Presentación de estudios realizados por Electroforesis e Inmunofijación en muestras de suero y orina de pacientes con "Discrasia de células plasmáticas"," appeared in the journal Bioquímica y Patología Clínica. This paper pertains to diagnostic techniques applied to serum and urine samples from patients with plasma cell dyscrasia. Another 2021 publication, "Wound Healing in the α2β1 Integrin-Deficient Mouse: Altered Keratinocyte Biology and Dysregulated Matrix Metalloproteinase Expression," featured in UNC Libraries, addresses molecular mechanisms in tissue repair using a genetically modified mouse model.

The scientist has frequently collaborated with researchers such as David G. Grenache, Zhonghua Zhang, Laura A. Wells, Jeffrey M. Davidson, and Mary M. Zutter. These collaborations likely contribute to the cross-disciplinary nature of their research endeavors.

Santoro's publication venues include:

  • Bioquímica y Patología Clínica/Bioquímica y patología clínica/Bioquímica y patología clínica
  • UNC Libraries

Their main fields of study encompass medicine with subfields including:

  • Rehabilitation
  • Molecular Biology
  • Immunology and Allergy

Key research topics covered in Santoro's work are:

  • Wound Healing and Treatments
  • Signaling Pathways in Disease
  • Cell Adhesion Molecules Research

Best Publications

  • Antiphospholipid Antibodies: Anticardiolipin and the Lupus Anticoagulant in Systemic Lupus Erythematosus (SLE) and in Non-SLE Disorders: Prevalence and Clinical Significance

    Paul E. Love;Samuel A. Santoro

  • Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen.

    Samuel A. Santoro

  • The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.

    W D Staatz;S M Rajpara;E A Wayner;W G Carter

  • Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.

    W D Staatz;K F Fok;M M Zutter;S P Adams

  • Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin

    Doris M. Haverstick;Doris M. Haverstick;Joseph F. Cowan;Joseph F. Cowan;Kenneth M. Yamada;Kenneth M. Yamada;Samuel A. Santoro;Samuel A. Santoro

  • The α2 integrin subunit-deficient mouse: A multifaceted phenotype including defects of branching morphogenesis and hemostasis

    Jianchun Chen;Thomas G. Diacovo;David G. Grenache;Samuel A. Santoro

  • The impact of heparin concentration and activated clotting time monitoring on blood conservation: A prospective, randomized evaluation in patients undergoing cardiac operation

    G.J. Despotis;J.H. Joist;C.W. Hogue;A. Alsoufiev

  • Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast.

    M M Zutter;G Mazoujian;S A Santoro

  • Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells

    Mary M. Zutter;Samuel A. Santoro;William D. Staatz;Ying L. Tsung

  • Inhibition of neointimal hyperplasia by blocking αvβ3 integrin with a small peptide antagonist GpenGRGDSPCA

    Eric T. Choi;Leslie Engel;Allan D. Callow;Shaping Sun

  • Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells

    Patricia J. Keely;Alan M. Fong;Mary M. Zutter;Samuel A. Santoro

  • Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin

    Gregory Bix;Jian Fu;Eva M. Gonzalez;Laura Macro

  • Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the α2β1 Integrin upon Release from Keratinocytes Migrating on Type I Collagen

    Jo Ann Dumin;S. Kent Dickeson;Thomas P. Stricker;Maitrayee Bhattacharyya-Pakrasi

  • Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation.

    G. J. Despotis;S. A. Santoro;E. Spitznagel;K. M. Kater

  • Decorin binds near the C terminus of type I collagen.

    Douglas R. Keene;James D. San Antonio;Richard Mayne;David J. McQuillan

  • Comparison of activated coagulation time and whole blood heparin measurements with laboratory plasma anti-Xa heparin concentration in patients having cardiac operations.

    G. J. Despotis;A. L. Summerfield;J. H. Joist;L. T. Goodnough

  • Widespread histologic distribution of the alpha 2 beta 1 integrin cell-surface collagen receptor.

    M. M. Zutter;S. A. Santoro

  • Tumor cell α3β1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis

    Hui Wang;Weili Fu;Jae Hong Im;Zengyi Zhou

  • Isolation and characterization of a heparin-binding domain from the amino terminus of platelet thrombospondin.

    V M Dixit;G A Grant;S A Santoro;W A Frazier

  • The platelet glycoprotein thrombospondin binds specifically to sulfated glycolipids.

    D D Roberts;D M Haverstick;V M Dixit;W A Frazier

Frequent Co-Authors

William A. Frazier
William A. Frazier Washington University in St. Louis
Gregory A. Grant
Gregory A. Grant Washington University in St. Louis
Lawrence T. Goodnough
Lawrence T. Goodnough Stanford University
Edward L. Spitznagel
Edward L. Spitznagel Washington University in St. Louis
Douglas M. Tollefsen
Douglas M. Tollefsen Washington University in St. Louis
Jeffrey M. Bergelson
Jeffrey M. Bergelson Children's Hospital of Philadelphia
Richard A.F. Clark
Richard A.F. Clark Stony Brook University
Roy Zent
Roy Zent Vanderbilt University Medical Center

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