2022 - Research.com Genetics and Molecular Biology in Taiwan Leader Award
2018 - Fellow, The World Academy of Sciences
2014 - Fellow, National Academy of Inventors
2012 - Fellow of the American Association for the Advancement of Science (AAAS)
Wen-Hwa Lee mainly focuses on Molecular biology, Cancer research, Retinoblastoma protein, Retinoblastoma and Cell biology. The various areas that he examines in his Molecular biology study include Regulation of gene expression, Gene, Exon, Cyclin D1 and Gene product. He combines subjects such as DNA damage, Carcinogenesis, Stem-cell therapy, Metastasis and Breast cancer with his study of Cancer research.
He has researched Retinoblastoma protein in several fields, including CDC2 Protein Kinase, Cyclin-dependent kinase 2 and Kinase activity. His Retinoblastoma research incorporates themes from Monoclonal antibody and SV40 large T antigen, Transfection. His Cell biology research integrates issues from CD44 and Programmed cell death.
His primary areas of investigation include Molecular biology, Cancer research, Gene, Cell biology and Retinoblastoma. His research in Molecular biology intersects with topics in Gene expression, Retinoblastoma protein, Exon, Cyclin D1 and Nuclear protein. The Cancer research study combines topics in areas such as Cancer, Cancer cell, Carcinogenesis, Metastasis and Breast cancer.
Genetics covers Wen-Hwa Lee research in Gene. His Cell biology research is multidisciplinary, relying on both Oxidative stress, Biochemistry, Programmed cell death and Kinetochore. The study incorporates disciplines such as Susceptibility gene, Allele, Tumor suppressor gene, Regulation of gene expression and Antibody in addition to Retinoblastoma.
His main research concerns Cancer research, Pancreatic cancer, Cancer cell, Metastasis and Cancer. His studies in Cancer research integrate themes in fields like Carcinogenesis, Tumor microenvironment, Phosphorylation, Tumor progression and Kinase. His studies deal with areas such as Cell culture, Malignancy, Cell growth, Immunology and Small molecule as well as Cancer cell.
Wen-Hwa Lee interconnects Antibody and Bioinformatics in the investigation of issues within Cancer. His work deals with themes such as Molecular biology and Cell biology, which intersect with Helicase. His Molecular biology study incorporates themes from Genome instability and Homologous recombination.
Wen-Hwa Lee spends much of his time researching Cancer research, Metastasis, Circulating tumor cell, Pancreatic cancer and Cancer. His Cancer research research incorporates themes from Epithelial–mesenchymal transition, Tumor progression, Immunology and Cancer cell. The concepts of his Epithelial–mesenchymal transition study are interwoven with issues in Tumor microenvironment, Cell cycle, Stromal cell and CD44.
The study incorporates disciplines such as Molecular biology and Epigenetics in addition to Metastasis. His study on Circulating tumor cell also encompasses disciplines like
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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
T. Durfee;K. Becherer;Phang-Lang Chen;Shiou-Hwei Yeh.
Genes & Development (1993)
Human retinoblastoma susceptibility gene: cloning, identification, and sequence
Wen-Hwa Lee;Robert Bookstein;Frank Hong;Lih-Jiuan Young.
Science (1987)
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
James A. DeCaprio;John W. Ludlow;James Figge;Jin-Yuh Shew.
Cell (1988)
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis.
Eva Y.-H. P. Lee;Chi-Yao Chang;Nanpin Hu;Yi-Chun J. Wang.
Nature (1992)
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation.
Phang-Lang Chen;Peter Scully;Jin-Yuh Shew;Jean Y.J. Wang.
Cell (1989)
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells
Huei-Jen Su Huang;Jiing-Kuan Yee;Jin-Yuh Shew;Phang-Lang Chen.
Science (1988)
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
David W. Goodrich;Nan Ping Wang;Yue-Wei Qian;Eva Y.-H.P. Lee.
Cell (1991)
The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity
Wen-Hwa Lee;Jin-Yuh Shew;Frank D. Hong;Theodore W. Sery.
Nature (1987)
Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene
Robert Bookstein;Jin-Yuh Shew;Phang-Lang Chen;Peter Scully.
Science (1990)
Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
Qing Zhong;Chi Fen Chen;Shang Li;Yumay Chen.
Science (1999)
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