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Chemistry

D-Index
58
Citations
10680
World Ranking
10748
National Ranking
332

Overview

Stefano Alcaro is affiliated with Magna Graecia University in Italy and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their research spans a range of interconnected disciplines focusing on molecular and chemical aspects of biological processes and diseases.

Their main subfields of study include Molecular Biology, Organic Chemistry, Pharmacology, Infectious Diseases, and Computational Theory and Mathematics. The scientist's work covers several prominent research topics, such as:

  • Cholinesterase and Neurodegenerative Diseases
  • Computational Drug Discovery Methods
  • SARS-CoV-2 and COVID-19 Research
  • Enzyme function and inhibition
  • Click Chemistry and Applications
  • DNA and Nucleic Acid Chemistry
  • RNA and protein synthesis mechanisms

Stefano Alcaro has published in a variety of scientific journals, with multiple contributions in notable venues such as:

  • European Journal of Medicinal Chemistry
  • Molecules
  • Pharmaceuticals
  • Journal of Medicinal Chemistry
  • International Journal of Molecular Sciences

Recent papers authored by Stefano Alcaro include:

  • Non-coding RNAs in cancer: platforms and strategies for investigating the genomic "dark matter" (2020), Journal of Experimental & Clinical Cancer Research
  • Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses (2020), Drug Resistance Updates
  • Improving the Treatment of Acute Lymphoblastic Leukemia (2020), Biochemistry
  • Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile (2022), Microbiology Spectrum
  • Pyrrolo[2',3':3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types (2020), Journal of Medicinal Chemistry

Frequent co-authors who have contributed alongside Stefano Alcaro are:

  • Giosuè Costa
  • Roberta Rocca
  • Anna Artese
  • Francesca Alessandra Ambrosio
  • Francesco Ortuso

The research profile of Stefano Alcaro reflects a multidisciplinary approach combining experimental and computational methods to address challenges in molecular biology, medicinal chemistry, and pharmacology, particularly in areas related to neurodegenerative diseases and viral infections including SARS-CoV-2.

Best Publications

  • The mechanisms of pharmacokinetic food-drug interactions - A perspective from the UNGAP group.

    Mirko Koziolek;Stefano Alcaro;Patrick Augustijns;Abdul W. Basit

  • Chalcones: a valid scaffold for monoamine oxidases inhibitors.

    Franco Chimenti;Rossella Fioravanti;Adriana Bolasco;Paola Chimenti

  • Synthesis, Molecular Modeling, and Selective Inhibitory Activity against Human Monoamine Oxidases of 3-Carboxamido-7-Substituted Coumarins†

    Franco Chimenti;Daniela Secci;Adriana Bolasco;Paola Chimenti

  • Non-coding RNAs in cancer: platforms and strategies for investigating the genomic “dark matter”

    Katia Grillone;Caterina Riillo;Francesca Scionti;Roberta Rocca

  • Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors

    Rossella Fioravanti;Adriana Bolasco;Fedele Manna;Francesca Rossi

  • Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives

    Fedele Manna;Franco Chimenti;Adriana Bolasco;Daniela Secci

  • Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives.

    Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  • Quercetin as the active principle of Hypericum hircinum exerts a selective inhibitory activity against MAO-A: Extraction, biological analysis, and computational study

    Franco Chimenti;Filippo Cottiglia;Leonardo Bonsignore;Laura Casu

  • Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.

    Alexandra Gaspar;Tiago Silva;Matilde Yáñez;Dolores Vina

  • Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach.

    Roberto Molinaro;Michael Evangelopoulos;Jessica R. Hoffman;Claudia Corbo

  • Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study

    Franco Chimenti;Daniela Secci;Adriana Bolasco;Paola Chimenti

  • Synthesis, Biological Evaluation, and Molecular Modeling of Oleuropein and Its Semisynthetic Derivatives as Cyclooxygenase Inhibitors

    Antonio Procopio;Stefano Alcaro;Monica Nardi;Manuela Oliverio

  • A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.

    Franco Chimenti;Rossella Fioravanti;Adriana Bolasco;Paola Chimenti

  • Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives.

    Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  • GBPM: GRID-based pharmacophore model: concept and application studies to protein--protein recognition

    Francesco Ortuso;Thierry Langer;Stefano Alcaro

  • Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations

    Federica Moraca;Jussara Amato;Francesco Ortuso;Anna Artese

  • Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives

    Daniela Secci;Simone Carradori;Adriana Bolasco;Paola Chimenti

  • Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.

    Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  • N-myristoylation determines dual targeting of mammalian NADH-cytochrome b(5) reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning

    Sara Colombo;Renato Longhi;Stefano Alcaro;Francesco Ortuso

  • Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties.

    Nicoletta Desideri;Adriana Bolasco;Rossella Fioravanti;Luca Proietti Monaco

  • Hybrid ligand–alkylating agents targeting telomeric G-quadruplex structures

    Filippo Doria;Matteo Nadai;Marco Folini;Marco Di Antonio

  • Modeling and biological evaluation of 3,3′-(1,2-ethanediyl)bis[2-(4-methoxyphenyl)-thiazolidin-4-one], a new synthetic cyclooxygenase-2 inhibitor

    Rosaria Ottaná;Emanuela Mazzon;Laura Dugo;Francesca Monforte

  • Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids.

    Simone Carradori;Maria Concetta Gidaro;Anél Petzer;Giosuè Costa

Frequent Co-Authors

Francesco Ortuso
Francesco Ortuso Magna Graecia University
Daniela Secci
Daniela Secci Sapienza University of Rome
Francesca Ceccherini-Silberstein
Francesca Ceccherini-Silberstein University of Rome Tor Vergata
Carlo Federico Perno
Carlo Federico Perno University of Milan
Simone Carradori
Simone Carradori University of Chieti-Pescara
Claudiu T. Supuran
Claudiu T. Supuran University of Florence
Fernanda Borges
Fernanda Borges University of Porto
Anne-Geneviève Marcelin
Anne-Geneviève Marcelin Sorbonne University
Maurizio Botta
Maurizio Botta University of Siena
Eugenio Uriarte
Eugenio Uriarte University of Santiago de Compostela

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