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Chemistry

D-Index
55
Citations
8335
World Ranking
12394
National Ranking
412

Overview

Daniela Secci is affiliated with Sapienza University of Rome in Italy and has contributed extensively to research in the fields of Biochemistry, Genetics and Molecular Biology, Chemistry, and Medicine. Their work spans several subfields including Molecular Biology, Organic Chemistry, Pharmacology, Biomedical Engineering, and Biomaterials.

Their research primarily focuses on topics related to enzyme function and inhibition, synthesis and catalytic reactions, and neurodegenerative disease mechanisms, especially those involving cholinesterase. Other notable areas of study include click chemistry and applications, phytochemistry and bioactive compounds, phenothiazines and benzothiazines synthesis and activities, as well as RNA interference and gene delivery.

Frequent publication venues for Daniela Secci include:

  • Molecules
  • European Journal of Medicinal Chemistry
  • Journal of Medicinal Chemistry
  • Pharmaceuticals
  • Journal of Enzyme Inhibition and Medicinal Chemistry

The scientist has collaborated frequently with several coauthors, among them Paolo Guglielmi, Simone Carradori, Claudiu T. Supuran, Emanuela Berrino, and Fabrizio Carta.

Significant publications by Daniela Secci include:

  • Metal-organic frameworks (MOFs) as biomolecules drug delivery systems for anticancer purposes, 2022, European Journal of Medicinal Chemistry
  • Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors, 2020, European Journal of Medicinal Chemistry
  • 1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors, 2020, Journal of Medicinal Chemistry
  • Synthesis and Biological Evaluation of Carvacrol-Based Derivatives as Dual Inhibitors of H. pylori Strains and AGS Cell Proliferation, 2020, Pharmaceuticals
  • Metabolic profiling of different wild and cultivated Allium species based on high-resolution mass spectrometry, high-performance liquid chromatography-photodiode array detector, and color analysis, 2020, Journal of Mass Spectrometry

Best Publications

  • Synthesis and pharmacological activity of 2-oxo-(2H) 1-benzopyran-3-carboxamide derivatives

    L Bonsignore;G Loy;D Secci;A Calignano

  • Chalcones: a valid scaffold for monoamine oxidases inhibitors.

    Franco Chimenti;Rossella Fioravanti;Adriana Bolasco;Paola Chimenti

  • Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein.

    Fedele Manna;Franco Chimenti;Rossella Fioravanti;Adriana Bolasco

  • Synthesis, Molecular Modeling, and Selective Inhibitory Activity against Human Monoamine Oxidases of 3-Carboxamido-7-Substituted Coumarins†

    Franco Chimenti;Daniela Secci;Adriana Bolasco;Paola Chimenti

  • Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives

    Fedele Manna;Franco Chimenti;Adriana Bolasco;Daniela Secci

  • Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives.

    Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  • Quercetin as the active principle of Hypericum hircinum exerts a selective inhibitory activity against MAO-A: Extraction, biological analysis, and computational study

    Franco Chimenti;Filippo Cottiglia;Leonardo Bonsignore;Laura Casu

  • Selective MAO-B inhibitors: a lesson from natural products

    Simone Carradori;Melissa D'Ascenzio;Paola Chimenti;Daniela Secci

  • A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone.

    Franco Chimenti;Bruna Bizzarri;Elias Maccioni;Daniela Secci

  • Synthesis and selective inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives against monoamine oxidase.

    Chimenti F;Bolasco A;Manna F;Secci D

  • The State of the Art of Pyrazole Derivatives as Monoamine Oxidase Inhibitors and Antidepressant/Anticonvulsant Agents

    D. Secci;A. Bolasco;P. Chimenti;S. Carradori

  • Synthesis, selective anti-Helicobacter pylori activity, and cytotoxicity of novel N-substituted-2-oxo-2H-1-benzopyran-3-carboxamides.

    Franco Chimenti;Bruna Bizzarri;Adriana Bolasco;Daniela Secci

  • Out of the active site binding pocket for carbonic anhydrase inhibitors

    Katia D'Ambrosio;Simone Carradori;Simona M. Monti;Martina Buonanno

  • Efficacy of Hypericum and Calendula oils in the epithelial reconstruction of surgical wounds in childbirth with caesarean section

    Silvio M. Lavagna;Daniela Secci;Paola Chimenti;Leonardo Bonsignore

  • Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study

    Franco Chimenti;Daniela Secci;Adriana Bolasco;Paola Chimenti

  • A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.

    Franco Chimenti;Rossella Fioravanti;Adriana Bolasco;Paola Chimenti

  • Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives.

    Franco Chimenti;Elias Maccioni;Daniela Secci;Adriana Bolasco

  • Synthesis and biological evaluation of novel 2,4-disubstituted-1,3-thiazoles as anti-Candida spp. agents

    Franco Chimenti;Bruna Bizzarri;Adriana Bolasco;Daniela Secci

  • Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives

    Daniela Secci;Simone Carradori;Adriana Bolasco;Paola Chimenti

  • Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.

    Franco Chimenti;Simone Carradori;Daniela Secci;Adriana Bolasco

Frequent Co-Authors

Simone Carradori
Simone Carradori University of Chieti-Pescara
Stefano Alcaro
Stefano Alcaro Magna Graecia University
Francesco Ortuso
Francesco Ortuso Magna Graecia University
Claudiu T. Supuran
Claudiu T. Supuran University of Florence
Antonello Mai
Antonello Mai Sapienza University of Rome
Luisa Mannina
Luisa Mannina Sapienza University of Rome
Marcello Locatelli
Marcello Locatelli University of Chieti-Pescara
Gokhan Zengin
Gokhan Zengin Selçuk University
Lucia Altucci
Lucia Altucci University of Campania "Luigi Vanvitelli"
Daniela Vullo
Daniela Vullo University of Florence

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