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64
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9678
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4269

Overview

Clemente Capasso is affiliated with the National Academies of Sciences, Engineering, and Medicine in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, chemistry, and medicine, with particular emphasis on molecular biology, organic chemistry, and pharmacology.

The scientist's work concentrates on enzyme function and inhibition, phenothiazines and benzothiazines synthesis and activities, synthesis and catalytic reactions, cholinesterase and neurodegenerative diseases, chemical reactions and mechanisms, polyamine metabolism and applications, and enzyme catalysis and immobilization.

Among recent publications authored or coauthored by Capasso are:

  • "Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment" (2020, Metabolites)
  • "Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase" (2021, Journal of Enzyme Inhibition and Medicinal Chemistry)
  • "An overview on the recently discovered iota-carbonic anhydrases" (2021, Journal of Enzyme Inhibition and Medicinal Chemistry)
  • "Bacterial ι-carbonic anhydrase: a new active class of carbonic anhydrase identified in the genome of the Gram-negative bacterium Burkholderia territorii" (2020, Journal of Enzyme Inhibition and Medicinal Chemistry)
  • "Antibacterial carbonic anhydrase inhibitors: an update on the recent literature" (2020, Expert Opinion on Therapeutic Patents)

Clemente Capasso frequently collaborates with several researchers, including:

  • Claudiu T. Supuran
  • Viviana De Luca
  • Andrea Angeli
  • Alessio Nocentini
  • Fabrizio Carta

Their research outputs have appeared most often in the following publication venues:

  • Journal of Enzyme Inhibition and Medicinal Chemistry
  • International Journal of Molecular Sciences
  • Expert Opinion on Therapeutic Patents
  • European Journal of Medicinal Chemistry
  • ChemMedChem

Their research contributions reflect interdisciplinary approaches within biochemistry, chemistry, and medicine, particularly focusing on enzymatic mechanisms, inhibitors, and synthetic chemistry related to biological and pharmacological applications.

Best Publications

  • An overview of the alpha-, beta- and gamma-carbonic anhydrases from Bacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?

    Clemente Capasso;Claudiu T Supuran

  • Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrases

    Sonia Del Prete;Daniela Vullo;Gillian Marie Fisher;Katherine Thea Andrews

  • Sulfa and trimethoprim-like drugs – antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitors

    Clemente Capasso;Claudiu T Supuran

  • Anti-infective carbonic anhydrase inhibitors: a patent and literature review.

    Clemente Capasso;Claudiu T Supuran

  • Bacterial, fungal and protozoan carbonic anhydrases as drug targets

    Clemente Capasso;Claudiu T Supuran

  • An Overview of the Bacterial Carbonic Anhydrases

    Claudiu T. Supuran;Clemente Capasso

  • Review on plug-in electric vehicle charging architectures integrated with distributed energy sources for sustainable mobility

    Luigi Rubino;Clemente Capasso;Ottorino Veneri

  • Experimental analysis on the performance of lithium based batteries for road full electric and hybrid vehicles

    Clemente Capasso;Ottorino Veneri

  • Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment.

    Andrea Angeli;Fabrizio Carta;Alessio Nocentini;Jean-Yves Winum

  • The η-class carbonic anhydrases as drug targets for antimalarial agents

    Claudiu T Supuran;Clemente Capasso

  • An α-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO2 hydration reaction.

    Viviana De Luca;Daniela Vullo;Andrea Scozzafava;Vincenzo Carginale

  • A magnificent enzyme superfamily: carbonic anhydrases, their purification and characterization

    Ozen Ozensoy Guler;Clemente Capasso;Claudiu T. Supuran

  • Biomimetic CO2 capture using a highly thermostable bacterial α-carbonic anhydrase immobilized on a polyurethane foam

    Fortunato Migliardini;Viviana De Luca;Vincenzo Carginale;Mosè Rossi

  • Toxicity, Accumulation, and Removal of Heavy Metals by Three Aquatic Macrophytes

    A. Basile;S. Sorbo;B. Conte;R. Castaldo Cobianchi

  • X‐ray structure of the first `extremo‐α‐carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1

    Anna Di Fiore;Clemente Capasso;Viviana De Luca;Simona Maria Monti

  • Biochemical properties of a novel and highly thermostable bacterial α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense YO3AOP1.

    Clemente Capasso;Viviana De Luca;Vincenzo Carginale;Raffaele Cannio

  • Crystal structure and kinetic studies of a tetrameric type II β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.

    Marta Ferraroni;Sonia Del Prete;Daniela Vullo;Clemente Capasso

  • The zinc coordination pattern in the η-carbonic anhydrase from Plasmodium falciparum is different from all other carbonic anhydrase genetic families.

    Giuseppina De Simone;Anna Di Fiore;Clemente Capasso;Claudiu Trandafir Supuran

  • DNA Cloning, Characterization, and Inhibition Studies of an α-Carbonic Anhydrase from the Pathogenic Bacterium Vibrio cholerae

    Sonia Del Prete;Semra Isik;Semra Isik;Daniela Vullo;Viviana De Luca

  • Biomedical applications of prokaryotic carbonic anhydrases.

    Claudiu T. Supuran;Clemente Capasso

Frequent Co-Authors

Claudiu T. Supuran
Claudiu T. Supuran University of Florence
Daniela Vullo
Daniela Vullo University of Florence
Zeid A. ALOthman
Zeid A. ALOthman King Saud University
Andrea Scozzafava
Andrea Scozzafava University of Florence
Mosè Rossi
Mosè Rossi National Research Council (CNR)
Fabrizio Carta
Fabrizio Carta University of Florence
Piero A. Temussi
Piero A. Temussi University of Naples Federico II
Giuseppina De Simone
Giuseppina De Simone National Research Council (CNR)
Jean-Yves Winum
Jean-Yves Winum University of Montpellier
Martino Bolognesi
Martino Bolognesi University of Milan

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