World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
61
Citations
13139
World Ranking
9255
National Ranking
665

Biology and Biochemistry

D-Index
60
Citations
12893
World Ranking
11950
National Ranking
849

Overview

Claus Jacob is affiliated with Saarland University in Germany and contributes primarily to the field of Materials Science. Their research encompasses several specialized subfields, including Materials Chemistry, Organic Chemistry, Nutrition and Dietetics, Plant Science, and Molecular Biology.

The scientist has a focused interest in multiple research topics such as:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Selenium in Biological Systems
  • Free Radicals and Antioxidants
  • Synthesis and Biological Evaluation
  • Ethnobotanical and Medicinal Plants Studies
  • Organoselenium and Organotellurium Chemistry

Claus Jacob's recent papers provide insight into their thematic areas and research trajectory. Notable publications include:

  • "GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design," 2023, Green Chemistry
  • "Selenium and tellurium in the development of novel small molecules and nanoparticles as cancer multidrug resistance reversal agents," 2022, Drug Resistance Updates
  • "Electrochemical Selenation/Cyclization of Quinones: A Rapid, Green and Efficient Access to Functionalized Trypanocidal and Antitumor Compounds," 2020, European Journal of Organic Chemistry
  • "Antimicrobial, Anticancer and Multidrug-Resistant Reversing Activity of Novel Oxygen-, Sulfur- and Selenoflavones and Bioisosteric Analogues," 2020, Pharmaceuticals
  • "Selenomethionine: A Pink Trojan Redox Horse with Implications in Aging and Various Age-Related Diseases," 2021, Antioxidants

The scientist commonly publishes in venues such as The Cambridge Structural Database, Sci, Current Nutraceuticals, Antioxidants, and Antibiotics.

Collaboration features prominently in Claus Jacob's work. Frequent co-authors include Muhammad Jawad Nasim, Cláudia Pessoa, Ahmad Yaman Abdin, Lutz Ackermann, and Pedro M. S. Costa, reflecting established research partnerships and joint efforts across several publications.

Best Publications

  • Sulfur and selenium: the role of oxidation state in protein structure and function.

    Claus Jacob;Gregory I. Giles;Niroshini M. Giles;Helmut Sies

  • Control of zinc transfer between thionein, metallothionein, and zinc proteins

    Claus Jacob;Wolfgang Maret;Bert L. Vallee

  • Metal and redox modulation of cysteine protein function.

    Niroshini M Giles;Aaron B Watts;Gregory I Giles;Fiona H Fry

  • Inhibitory sites in enzymes: Zinc removal and reactivation by thionein

    Wolfgang Maret;Claus Jacob;Bert L. Vallee;Edmond H. Fischer

  • A scent of therapy: pharmacological implications of natural products containing redox-active sulfur atoms

    Claus Jacob

  • Tellurium: an element with great biological potency and potential.

    Lalla Aicha Ba;Mandy Döring;Vincent Jamier;Claus Jacob

  • Reactive sulfur species: an emerging concept in oxidative stress.

    Gregory I. Giles;Claus Jacob

  • Hypothesis: the role of reactive sulfur species in oxidative stress.

    Gregory I. Giles;Karen M. Tasker;Claus Jacob

  • Oxidative activation of antioxidant defence

    Paul G. Winyard;Christopher J. Moody;Claus Jacob

  • Polysulfides as biologically active ingredients of garlic

    Ute Münchberg;Awais Anwar;Susanne Mecklenburg;Claus Jacob

  • Multiple roles of cysteine in biocatalysis.

    Niroshini M Giles;Gregory I Giles;Claus Jacob

  • Natural Nanoparticles: A Particular Matter Inspired by Nature

    Sharoon Griffin;Muhammad Irfan Masood;Muhammad Irfan Masood;Muhammad Jawad Nasim;Muhammad Sarfraz

  • 1,4-naphthoquinones: from oxidative damage to cellular and inter-cellular signaling.

    Lars-Oliver Klotz;Xiaoqing Hou;Claus Jacob

  • A Comparison of the Antibacterial and Antifungal Activities of Thiosulfinate Analogues of Allicin.

    Roman Leontiev;Roman Leontiev;Nils Hohaus;Claus Jacob;Martin C. H. Gruhlke

  • Selenium- and Tellurium-Containing Multifunctional Redox Agents as Biochemical Redox Modulators with Selective Cytotoxicity

    Vincent Jamier;Lalla A. Ba;Claus Jacob

  • The sulfinic acid switch in proteins

    Claus Jacob;Andrea L. Holme;Fiona H. Fry

  • Selenium redox biochemistry of zinc–sulfur coordination sites in proteins and enzymes

    Claus Jacob;Wolfgang Maret;Bert L. Vallee

  • Aspects of the biological redox chemistry of cysteine: from simple redox responses to sophisticated signalling pathways.

    Claus Jacob;Iona Knight;Paul G. Winyard

  • Synthesis and selective anticancer activity of organochalcogen based redox catalysts.

    Mandy Doering;Lalla A. Ba;Nils Lilienthal;Carole Nicco

  • Dimethyl fumarate, a two-edged drug: Current status and future directions.

    Nathaniel Edward Bennett Saidu;Niloufar Kavian;Niloufar Kavian;Karen Leroy;Claus Jacob

  • Control of oxidative posttranslational cysteine modifications: from intricate chemistry to widespread biological and medical applications.

    Claus Jacob;Eric Battaglia;Torsten Burkholz;Du Peng

Frequent Co-Authors

Gilbert Kirsch
Gilbert Kirsch University of Lorraine
Marc Diederich
Marc Diederich Seoul National University
Paul G. Winyard
Paul G. Winyard University of Exeter
Wolfgang Maret
Wolfgang Maret King's College London
Mario Dicato
Mario Dicato Centre Hospitalier de Luxembourg
Florenz Sasse
Florenz Sasse Technische Universität Braunschweig
Bert L. Vallee
Bert L. Vallee Harvard University
Ludger A. Wessjohann
Ludger A. Wessjohann Leibniz Association
Sergio Valente
Sergio Valente Sapienza University of Rome
Lutz Ackermann
Lutz Ackermann University of Göttingen

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