James T. MacGregor

Research.com Recognitions

• 1982 - Fellow of the Royal Society of Canada Academy of Science

Overview

Best Publications

• Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage

  Benjamin C. Blount;Matthew M. Mack;Carol M. Wehr;James T. MacGregor

  1792
  Citations

• The induction of micronuclei as a measure of genotoxicity: A report of the U.S. environmental protection agency Gene-Tox program☆

  John A. Heddle;Mark Hite;Barbara Kirkhart;Kathleen Mavournin

  1085
  Citations

• Micronuclei as an index of cytogenetic damage: Past, present, and future

  J. A. Heddle;M. C. Cimino;M. Hayashi;F. Romagna

  742
  Citations

• Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.

  Marilyn J. Aardema;James T. MacGregor

  533
  Citations

• Guidelines for the conduct of micronucleus assays in mammalian bone marrow erythrocytes.

  James T. MacGregor;John A. Heddle;Mark Hite;Barry H. Margolin

  477
  Citations

• In vivo rodent erythrocyte micronucleus assay.

  Makoto Hayashi;Raymond R. Tice;James T. MacGregor;Diana Anderson

  432
  Citations

• Mutagenicity of plant flavonoids: structural requirements for mutagenic activity in Salmonella typhimurium.

  James T. Macgregor;Leonard Jurd

  427
  Citations

• Clastogen-induced micronuclei in peripheral blood erythrocytes: The basis of an improved micronucleus test

  James T. MacGregor;Carol M. Wehr;Daniel H. Gould

  339
  Citations

• In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring.

  Makoto Hayashi;James T. MacGregor;David G. Gatehouse;Ilse-Dore Adler

  337
  Citations

• Trivalent Chromium: Assessing the Genotoxic Risk of an Essential Trace Element and Widely Used Human and Animal Nutritional Supplement

  David A. Eastmond;James T. MacGregor;Ronald S. Slesinski

  335
  Citations

• The in vivo erythrocyte micronucleus test: measurement at steady state increases assay efficiency and permits integration with toxicity studies.

  James T. Macgregor;Carol M. Wehr;Philip R. Henika;Michael D. Shelby

  213
  Citations

• Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity

  Kendall B. Wallace;Elizabeth Hausner;Eugene Herman;Eugene Herman;Gordon D. Holt

  209
  Citations

• The persistence of micronuclei in peripheral blood erythrocytes: detection of chronic chromosome breakage in mice

  Robert Schlegel;Robert Schlegel;James T. MacGregor;James T. MacGregor

  183
  Citations

• Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing

  V. Thybaud;M. Aardema;J. Clements;K. Dearfield

  165
  Citations

• In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test.

  Makoto Hayashi;James T MacGregor;David G Gatehouse;David H Blakey

  162
  Citations

• Association of Marginal Folate Depletion With Increased Human Chromosomal Damage In Vivo: Demonstration by Analysis of Micronucleated Erythrocytes

  Richard B. Everson;Carol M. Wehr;Gregory L Erexson;James T. MacGregor

  162
  Citations

• 'Spontaneous' genetic damage in man: evaluation of interindividual variability, relationship among markers of damage, and influence of nutritional status.

  James T MacGregor;Carol M Wehr;Robert A Hiatt;Beverly Peters

  153
  Citations

• The persistence of micronucleated erythrocytes in the peripheral circulation of normal and splenectomized Fischer 344 rats: implications for cytogenetic screening.

  Robert Schlegel;Robert Schlegel;James T. MacGregor;James T. MacGregor

  152
  Citations

• Genetic effects of the flavonols quercetin, kaempferol, and galangin on Chinese hamster ovary cells in vitro.

  J.H. Carver;A.V. Carrano;J.T. MacGregor

  150
  Citations

• Induction of hepatic mutations in lacI transgenic mice

  Jon C. Mirsalis;G.Scott Provost;Crystal D. Matthews;Richard T. Hamner

  149
  Citations