Nicolaas G. J. Jaspers

Overview

Best Publications

• A SINGLE ATAXIA TELANGIECTASIA GENE WITH A PRODUCT SIMILAR TO PI-3 KINASE

  Kinneret Savitsky;Anat Bar-Shira;Shlomit Gilad;Galit Rotman

  3708
  Citations

• Molecular mechanism of nucleotide excision repair

  W. L. De Laat;N. G. J. Jaspers;J. H. J. Hoeijmakers

  1454
  Citations

• A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

  Laura J. Niedernhofer;George A. Garinis;Anja Raams;Astrid S. Lalai

  750
  Citations

• Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

  Anneke M. Sijbers;Wouter L. De Laat;Rafael R. Ariza;Maureen Biggerstaff

  681
  Citations

• The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks

  Laura J. Niedernhofer;Hanny Odijk;Magda Budzowska;Ellen van Drunen

  616
  Citations

• Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells

  Tomoo Ogi;Siripan Limsirichaikul;Siripan Limsirichaikul;René M. Overmeer;Marcel Volker

  460
  Citations

• DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair

  Wouter L. de Laat;Esther Appeldoorn;Kaoru Sugasawa;Eric Weterings

  460
  Citations

• SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

  C. Stoepker;K. Hain;B. Schuster;Y. Hilhorst-Hofstee

  406
  Citations

• A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A

  Giuseppina Giglia-Mari;Frederic Coin;Jeffrey A Ranish;Deborah Hoogstraten

  386
  Citations

• Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia.

  Massimo Bogliolo;Beatrice Schuster;Chantal Stoepker;Burak Derkunt

  375
  Citations

• Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions.

  Maria Kraakman-van der Zwet;Wilhelmina J. I. Overkamp;Rebecca E. E. van Lange;Jeroen Essers

  355
  Citations

• Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene

  Elaine M. Taylor;Bernard C. Broughton;Elena Botta;Miria Stefanini

  352
  Citations

• Predominance of null mutations in ataxia-telangiectasia

  Shlomit Gilad;Rami Khosravi;Dganit Shkedy;Tamar Uziel

  336
  Citations

• Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy.

  Wim J. Kleijer;Vincent Laugel;Mark Berneburg;Tiziana Nardo

  322
  Citations

• DNA Structural Elements Required for ERCC1-XPF Endonuclease Activity

  Wouter L. de Laat;Esther Appeldoorn;Nicolaas G.J. Jaspers;Jan H.J. Hoeijmakers

  314
  Citations

• First Reported Patient with Human ERCC1 Deficiency Has Cerebro-Oculo-Facio-Skeletal Syndrome with a Mild Defect in Nucleotide Excision Repair and Severe Developmental Failure

  Nicolaas G.J. Jaspers;Anja Raams;Margherita Cirillo Silengo;Nils Wijgers

  260
  Citations

• MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

  Joris Pothof;Nicole S Verkaik;Wilfred van IJcken;Erik A C Wiemer

  248
  Citations

• Genetic complementation analysis of ataxia telangiectasia and Nijmegen breakage syndrome: a survey of 50 patients.

  N.G.J. Jaspers;R.A. Gatti;C. Baan;P.C.M.L. Linssen

  245
  Citations

• Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome

  Katsuyoshi Horibata;Yuka Iwamoto;Isao Kuraoka;Nicolaas G. J. Jaspers

  241
  Citations

• Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.

  A. J. Van Vuuren;E. Appeldoorn;H. Odijk;A. Yasui

  234
  Citations