World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
61
Citations
10916
World Ranking
1918
National Ranking
951

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Peter J. Stambrook is affiliated with the University of Cincinnati Medical Center in the United States and has a research focus spanning Medicine, Biochemistry, Genetics, and Molecular Biology. Their work emphasizes oncology, molecular biology, and cell biology, with additional contributions to neuroscience and biological psychiatry.

The scientist's recent publications demonstrate engagement with multiple aspects of cancer biology, bone metabolism, and molecular mechanisms. Notable recent papers include:

  • "Therapeutically leveraging GABAA receptors in cancer" (2021, Experimental Biology and Medicine)
  • "Treatment of osteoporosis with a modified zeolite shows beneficial effects in an osteoporotic rat model and a human clinical trial" (2020, Experimental Biology and Medicine)
  • "BRUCE preserves genomic stability in the male germline of mice" (2020, Cell Death and Differentiation)
  • "Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer" (2024, Nature Communications)
  • "Nardilysin-Regulated Scission Mechanism Activates Polo-like Kinase 3 to Suppress the Development of Pancreatic Cancer" (2022, bioRxiv (Cold Spring Harbor Laboratory))

Key coauthors frequently collaborating with Peter J. Stambrook include Jianhua Ling, Chi-Lin Tsai, Wenjuan Yin, Yu Cao, and Ya'an Kang.

The scientist has published multiple works in the following venues:

  • Experimental Biology and Medicine
  • Cell Death and Differentiation
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)

Research topics covered by their work include:

  • Microtubule and mitosis dynamics
  • Pancreatic and Hepatic Oncology Research
  • Neuroscience and Neuropharmacology Research
  • Tryptophan and brain disorders
  • Cancer, Stress, Anesthesia, and Immune Response
  • Bone health and osteoporosis research
  • Bone Metabolism and Diseases

Fields of study associated with Peter J. Stambrook's research comprise Medicine and Biochemistry, Genetics and Molecular Biology, with subfields including Oncology, Molecular Biology, Cell Biology, Cellular and Molecular Neuroscience, and Biological Psychiatry.

Peter J. Stambrook has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2007.

Best Publications

  • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy.

    Wan Li Bi;Linda M. Parysek;Ronald Warnick;Peter J. Stambrook

  • Embryonic stem cells and somatic cells differ in mutation frequency and type

    Rachel B. Cervantes;James R. Stringer;Changshun Shao;Jay A. Tischfield

  • Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression

    Patrick E. Carroll;Masaru Okuda;Henning F. Horn;Paul Biddinger

  • Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation.

    Yiling Hong;Peter J. Stambrook

  • Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway.

    Suqing Xie;Huiyun Wu;Qi Wang;John P. Cogswell

  • The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle

    Nicholas C. Denko;Amato J. Giaccia;James R. Stringer;Peter J. Stambrook

  • The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.

    Harold I Saavedra;Jeffrey A Knauf;Jill M Shirokawa;Jianwei Wang

  • Altered hematopoiesis, behavior, and sexual function in μ opioid receptor-deficient mice

    Mingting Tian;Hal E. Broxmeyer;Yi Fan;Zhennan Lai

  • Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways

    El Mustapha Bahassi;Christopher W Conn;David L Myer;Robert F Hennigan

  • The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage.

    E M Bahassi;J L Ovesen;A L Riesenberg;W Z Bernstein

  • Hypoxic Activation of Nuclear Factor-κB Is Mediated by a Ras and Raf Signaling Pathway and Does Not Involve MAP Kinase (ERK1 or ERK2)

    Albert C. Koong;Eunice Y. Chen;Nahid F. Mivechi;Nicholas C. Denko

  • Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement.

    Michael K. Dush;James M. Sikela;Sohaib A. Khan;Jay A. Tischfield

  • DNA Repair in Murine Embryonic Stem Cells and Differentiated Cells

    Elisia D. Tichy;Peter J. Stambrook

  • The Role of the p53 Tumor Suppressor Gene in Squamous Cell Carcinoma of the Head and Neck

    John K. Field;Zlatko P. Pavelic;Demetrios A. Spandidos;Peter J. Stambrook

  • Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks.

    Elisia D. Tichy;Resmi Pillai;Li Deng;Li Liang

  • Human Prk Is a Conserved Protein Serine/Threonine Kinase Involved in Regulating M Phase Functions

    Bin Ouyang;Huiqi Pan;Luo Lu;Jian Li

  • High Frequency in Vivo Loss of Heterozygosity Is Primarily a Consequence of Mitotic Recombination

    P K Gupta;A Sahota;S A Boyadjiev;S Bye

  • Protein and messenger RNA expression of connexin43 in astrocytomas: implications in brain tumor gene therapy

    Nobusada Shinoura;Lin Chen;Maqsood A. Wani;Young Gyu Kim

  • Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration.

    Wei Huang;Wei Huang;Yuliang Feng;Jialiang Liang;Hao Yu

  • Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.

    S J Engle;M G Stockelman;J Chen;G Boivin

Frequent Co-Authors

Jay A. Tischfield
Jay A. Tischfield Rutgers, The State University of New Jersey
Changshun Shao
Changshun Shao Soochow University
James R. Stringer
James R. Stringer University of Cincinnati
George F. Babcock
George F. Babcock University of Cincinnati
Krešimir Pavelić
Krešimir Pavelić University of Rijeka
Ju Chen
Ju Chen University of California, San Diego
Gregory P. Boivin
Gregory P. Boivin Wright State University
Amato J. Giaccia
Amato J. Giaccia Stanford University
Hsiao Sheng Liu
Hsiao Sheng Liu National Cheng Kung University
James M. Sikela
James M. Sikela University of Colorado Denver

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