Sylvie Robine mainly investigates Cell biology, Intestinal epithelium, Cellular differentiation, Wnt signaling pathway and Intestinal mucosa. Sylvie Robine studies Catenin, a branch of Cell biology. Her study focuses on the intersection of Intestinal epithelium and fields such as Cell growth with connections in the field of Paneth cell and Progenitor cell.
Her work carried out in the field of Cellular differentiation brings together such families of science as Cell culture, Immunology, Pancreas, Stem cell and Notch signaling pathway. Her research integrates issues of KRAS and Goblet cell in her study of Wnt signaling pathway. While the research belongs to areas of Intestinal mucosa, Sylvie Robine spends her time largely on the problem of Epithelium, intersecting her research to questions surrounding Transgene, Somatic recombination and Cre recombinase.
Sylvie Robine focuses on Cell biology, Cancer research, Villin, Molecular biology and Colorectal cancer. Her Cell biology study integrates concerns from other disciplines, such as Cellular differentiation, Intestinal mucosa and Intestinal epithelium. In Cellular differentiation, she works on issues like Notch signaling pathway, which are connected to Transcription factor.
Her work deals with themes such as Carcinogenesis, Pathology, KRAS, Signal transduction and Metastasis, which intersect with Cancer research. The various areas that she examines in her Villin study include Epithelium, Actin cytoskeleton and Gene, Transgene. Her Colorectal cancer study combines topics in areas such as Oncogene, Angiogenesis, Immunology and Oncology.
Her scientific interests lie mostly in Cell biology, Cancer research, Colorectal cancer, Epithelium and Internal medicine. Her Cell biology research focuses on Homeostasis, Actin, Villin, Progenitor cell and Stem cell. The study incorporates disciplines such as Intestinal epithelium and Cell fate determination in addition to Progenitor cell.
Sylvie Robine has included themes like Wnt signaling pathway and Cellular differentiation in her Stem cell study. Her Cancer research research incorporates themes from Stroma, Bioinformatics, Organoid and Transforming growth factor beta, Signal transduction. The concepts of her Internal medicine study are interwoven with issues in Cell junction, Endocrinology and Oncology.
Cell biology, Intestinal mucosa, Colorectal cancer, Pathology and Inflammation are her primary areas of study. Her is doing research in Villin, Actin, Stem cell, Progenitor cell and Homeostasis, both of which are found in Cell biology. The Stem cell study combines topics in areas such as Unfolded protein response, Endoplasmic reticulum, Intestinal epithelium and Regeneration.
Her Intestinal mucosa research is multidisciplinary, relying on both Cellular differentiation, Actin cytoskeleton, LRP5, LRP6 and LGR5. Her research investigates the link between Colorectal cancer and topics such as Cancer research that cross with problems in Oncogene, Organoid, KRAS, Signal transduction and Genetically modified mouse. Her studies deal with areas such as Transforming growth factor beta, Matrigel and Adenocarcinoma as well as Pathology.
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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H. van Es;Marielle E. van Gijn;Orbicia Riccio;Maaike van den Born.
Nature (2005)
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
Adriana Donovan;Adriana Donovan;Christine A. Lima;Christine A. Lima;Jack L. Pinkus;Geraldine S. Pinkus.
Cell Metabolism (2005)
Notch signals control the fate of immature progenitor cells in the intestine
Silvia Fre;Mathilde Huyghe;Philippos Mourikis;Philippos Mourikis;Sylvie Robine.
Nature (2005)
Tissue-specific and inducible cre-mediated recombination in the gut epithelium
Fatima El Marjou;Klaus-Peter Janssen;Benny Hung-Junn Chang;Mei Li.
Genesis (2004)
Wnt/β-Catenin Is Essential for Intestinal Homeostasis and Maintenance of Intestinal Stem Cells
Tea Fevr;Sylvie Robine;Daniel Louvard;Joerg Huelsken.
Molecular and Cellular Biology (2007)
Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
Hiromi Gunshin;Yuko Fujiwara;Angel O. Custodio;Cristina DiRenzo.
Journal of Clinical Investigation (2005)
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
Pauline Bastide;Charbel Darido;Julie Pannequin;Ralf Kist.
Journal of Cell Biology (2007)
The co-workers of actin filaments: from cell structures to signals
Céline Revenu;Rafika Athman;Sylvie Robine;Daniel Louvard.
Nature Reviews Molecular Cell Biology (2004)
Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine
Silvia Fre;S. K. Pallavi;Mathilde Huyghe;Marick Laé.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.
Pauline Andreu;Sabine Colnot;Cécile Godard;Sophie Gad.
Development (2005)
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