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Biology and Biochemistry

D-Index
52
Citations
8227
World Ranking
16831
National Ranking
376

Overview

J. Ignacio Casal is affiliated with the Spanish National Research Council in Spain. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine, with a significant focus on Molecular Biology, Oncology, Cancer Research, Immunology, and Pathology and Forensic Medicine.

Their recent publications cover various aspects of cancer biology and diagnostic technologies. Notable papers include:

  • Proteomic Analysis of Low-Grade, Early-Stage Endometrial Carcinoma Reveals New Dysregulated Pathways Associated with Cell Death and Cell Signaling (2021, Cancers)
  • Interleukin 13 receptor alpha 2 (IL13Rα2): Expression, signaling pathways and therapeutic applications in cancer (2022, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer)
  • Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells (2020, Cancers)
  • Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer (2021, Engineering)
  • SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166 (2020, Oncogene)

The frequently collaborating coauthors include Vivian de los Ríos, Rubén A. Bartolomé, Ángela Martín-Regalado, Marta Jaén, and Javier Robles.

J. Ignacio Casal has published most frequently in the journals:

  • Cancers
  • Cells
  • Cell Death and Disease
  • IBJ Plus
  • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Their research focuses on topics such as:

  • Cancer, Lipids, and Metabolism
  • Advanced Proteomics Techniques and Applications
  • Genetic factors in colorectal cancer
  • Ferroptosis and cancer prognosis
  • Cancer Cells and Metastasis
  • Platelet Disorders and Treatments
  • Cell Adhesion Molecules Research

Best Publications

  • Proteome profiling of cancer-associated fibroblasts identifies novel proinflammatory signatures and prognostic markers for colorectal cancer.

    Sofía Torres;Rubén Álvaro Bartolomé;Marta Mendes;Rodrigo Barderas

  • Proteomic expression analysis of colorectal cancer by two-dimensional differential gel electrophoresis.

    Patricia Alfonso;Antonio Núñez;Juan Madoz-Gurpide;Luis Lombardia

  • Baculovirus Expression of Proteins of Porcine Reproductive and Respiratory Syndrome Virus Strain Olot/91. Involvement of ORF3 and ORF5 Proteins in Protection

    Alicia Urniza;Isabel Climent;Juan Plana Duran;Elena Corte´s

  • Affinity maturation of antibodies assisted by in silico modeling

    Rodrigo Barderas;Johan Desmet;Peter Timmerman;Rob H. Meloen

  • First peptide vaccine providing protection against viral infection in the target animal: studies of canine parvovirus in dogs.

    J. P. M. Langeveld;J. I. Casal;A. D. M. E. Osterhaus;E. Cortes

  • Identification of Tumor-associated Autoantigens for the Diagnosis of Colorectal Cancer in Serum Using High Density Protein Microarrays

    Ingrid Babel;Rodrigo Barderas;Ramón Díaz-Uriarte;Jorge Luis Martínez-Torrecuadrada

  • Control of oligomeric enzyme thermostability by protein engineering

    Tim J. Ahern;Jose I. Casal;Gregory A. Petsko;Alexander M. Klibanov

  • Effect of different baculovirus inactivation procedures on the integrity and immunogenicity of porcine parvovirus-like particles.

    Paloma Rueda;Jesús Fominaya;Jan P.M Langeveld;Christianne Bruschke

  • High Expression of IL-13 Receptor α2 in Colorectal Cancer Is Associated with Invasion, Liver Metastasis, and Poor Prognosis

    Rodrigo Barderas;Rubén A. Bartolomé;María Jesús Fernandez-Aceñero;Sofia Torres

  • C Terminus of Infectious Bursal Disease Virus Major Capsid Protein VP2 Is Involved in Definition of the T Number for Capsid Assembly

    José R. Castón;Jorge L. Martı́nez-Torrecuadrada;Antonio Maraver;Eleuterio Lombardo

  • CD8α2 CD11b+ Dendritic Cells Present Exogenous Virus-like Particles to CD8+ T Cells and Subsequently Express CD8α and CD205 Molecules

    Gabriel L. Morón;Paloma Rueda;J. Ignacio Casal;Claude D. Leclerc

  • Targeting the Extracellular Domain of Fibroblast Growth Factor Receptor 3 with Human Single-Chain Fv Antibodies Inhibits Bladder Carcinoma Cell Line Proliferation

    Jorge Luis Martínez-Torrecuadrada;Gabriela Cifuentes;P. Lopez-Serra;Pilar Sáenz

  • A novel recombinant virus-like particle vaccine for prevention of porcine parvovirus-induced reproductive failure.

    Adriaan F.G. Antonis;Christianne J.M. Bruschke;Paloma Rueda;Luis Maranga

  • In-depth Characterization of the Secretome of Colorectal Cancer Metastatic Cells Identifies Key Proteins in Cell Adhesion, Migration, and Invasion

    Rodrigo Barderas;Marta Mendes;Sofía Torres;Rubén Álvaro Bartolomé

  • Development of an antigen presentation system based on plum pox potyvirus

    M.Rosario Fernández-Fernández;Jorge L Martı́nez-Torrecuadrada;J.Ignacio Casal;Juan Antonio Garcı́a

  • Inactivated recombinant plant virus protects dogs from a lethal challenge with canine parvovirus.

    Jan P.M Langeveld;Frank R Brennan;Jorge L Martı́nez-Torrecuadrada;Tim D Jones

  • A Proteomics Analysis of Cell Signaling Alterations in Colorectal Cancer

    Juan Madoz-Gúrpide;Marta Cañamero;Lydia Sanchez;José Solano

  • LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival

    Sofía Torres;Irene Garcia-Palmero;Mercedes Herrera;Rubén A. Bartolomé

  • Proteome Analysis of Membrane Fractions in Colorectal Carcinomas by Using 2D-DIGE Saturation Labeling

    Patricia Alfonso;Marta Cañamero;Francisco Fernández-Carbonié;Antonio Núñez

  • DIFFERENTIAL PROTEIN EXPRESSION ON THE CELL SURFACE OF COLORECTAL CANCER CELLS ASSOCIATED TO TUMOR METASTASIS

    Jose Luis Luque-García;Jorge Luis Martínez-Torrecuadrada;Carolina Epifano;Marta Cañamero

Frequent Co-Authors

Antonio García de Herreros
Antonio García de Herreros Pompeu Fabra University
Jan P. M. Langeveld
Jan P. M. Langeveld Wageningen University & Research
Rob H. Meloen
Rob H. Meloen Pepscan (Netherlands)
Jaime Sancho
Jaime Sancho Spanish National Research Council
Alberto Muñoz
Alberto Muñoz Spanish National Research Council
Francisco J. Blanco
Francisco J. Blanco University of A Coruña
Isabel Fabregat
Isabel Fabregat University of Barcelona
Juan Pablo Albar
Juan Pablo Albar Spanish National Research Council
Juan Antonio Vizcaíno
Juan Antonio Vizcaíno European Bioinformatics Institute
Juan Antonio García
Juan Antonio García Spanish National Research Council

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