World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
51
Citations
8087
World Ranking
4359
National Ranking
161

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Virus

Jan P. M. Langeveld spends much of his time researching Virology, Scrapie, Bovine spongiform encephalopathy, Genotype and Pathology. His Virology research focuses on Parvovirus in particular. He carries out multidisciplinary research, doing studies in Scrapie and Proteinase K.

The study incorporates disciplines such as Transmissible spongiform encephalopathy and Epitope mapping in addition to Bovine spongiform encephalopathy. His PrPSc Proteins research focuses on subjects like Phenotype, which are linked to Disease. His Peptide sequence research is multidisciplinary, incorporating elements of Epitope and Monoclonal antibody.

His most cited work include:

  • Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie. (318 citations)
  • The goodpastiure autoantigen; mapping the major conformational epitope(s) of alpha3(IV) collagen to residues 17-31 and 127-141 of the NC-1 domain (171 citations)
  • Incidence and spectrum of sporadic Creutzfeldt–Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification (168 citations)

What are the main themes of his work throughout his whole career to date?

Jan P. M. Langeveld mainly investigates Virology, Scrapie, Bovine spongiform encephalopathy, Antibody and Epitope. His work deals with themes such as Peptide sequence and Monoclonal antibody, which intersect with Virology. His Scrapie study combines topics from a wide range of disciplines, such as Genotype and PRNP.

His Bovine spongiform encephalopathy study combines topics in areas such as Veterinary medicine and PrPSc Proteins. His Epitope research integrates issues from Molecular biology and Viral protein. His research integrates issues of Immunogenicity and Peptide vaccine in his study of Parvovirus.

He most often published in these fields:

  • Virology (56.80%)
  • Scrapie (50.40%)
  • Bovine spongiform encephalopathy (33.60%)

What were the highlights of his more recent work (between 2014-2021)?

  • Scrapie (50.40%)
  • Virology (56.80%)
  • Bovine spongiform encephalopathy (33.60%)

In recent papers he was focusing on the following fields of study:

His main research concerns Scrapie, Virology, Bovine spongiform encephalopathy, PRNP and Veterinary medicine. Jan P. M. Langeveld has included themes like Genetics, Genotyping, Genotype and Allele in his Scrapie study. His Virology research is multidisciplinary, incorporating elements of PrPSc Proteins, Incubation period, Western blot and Prion protein.

His PrPSc Proteins research incorporates elements of Immunohistochemistry and Staining. His Bovine spongiform encephalopathy research includes themes of Prion strain, Transmissible spongiform encephalopathy, Neuropathology and Spinal cord. Jan P. M. Langeveld works mostly in the field of PRNP, limiting it down to topics relating to Goat Diseases and, in certain cases, Polymorphism.

Between 2014 and 2021, his most popular works were:

  • Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats (24 citations)
  • Effect of Q211 and K222 PRNP Polymorphic Variants in the Susceptibility of Goats to Oral Infection With Goat Bovine Spongiform Encephalopathy (24 citations)
  • Prion protein genotype survey confirms low frequency of scrapie-resistant K222 allele in British goat herds (16 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Virus

His scientific interests lie mostly in Scrapie, PRNP, Veterinary medicine, Goat Diseases and Genotype. His research ties Bovine spongiform encephalopathy and Scrapie together. His work in the fields of Herd overlaps with other areas such as Breeding program.

His studies in Genotype integrate themes in fields like Infectivity, Genetically modified mouse, Incubation period and Virology. His Incubation period research includes elements of Immunohistochemistry, Staining, PrPSc Proteins, Blot and Epitope. His Virology research is multidisciplinary, incorporating perspectives in Western blot and Cerebellar cortex.

Best Publications

  • Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie.

    L. J. M. van Keulen;B. E. C. Schreuder;R. H. Meloen;G. Mooij-Harkes

  • Variably protease‐sensitive prionopathy: A new sporadic disease of the prion protein

    Wen Quan Zou;Gianfranco Puoti;Xiangzhu Xiao;Jue Yuan

  • Incidence and spectrum of sporadic Creutzfeldt–Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification

    Piero Parchi;Rosaria Strammiello;Silvio Notari;Armin Giese

  • The goodpastiure autoantigen; mapping the major conformational epitope(s) of alpha3(IV) collagen to residues 17-31 and 127-141 of the NC-1 domain

    Kai-Olaf Netzer;Anu Leinonen;Ariel Boutaud;Dorin-Bogdan Borza

  • Pathogenesis of natural scrapie in sheep

    L. J. M. van Keulen;B. E. C. Schreuder;M. E. W. Vromans;J. P. M. Langeveld

  • Tonsillar biopsy and PrPSc detection in the preclinical diagnosis of scrapie

    B. E. C. Schreuder;L. J. M. van Keulen;M. E. W. Vromans;J. P. M. Langeveld

  • Structural aspects of antibody-antigen interaction revealed through small random peptide libraries

    Jerry W. Slootstra;Wouter C. Puijk;Gerard J. Ligtvoet;Jan P. M. Langeveld

  • Enzymatic degradation of prion protein in brain stem from infected cattle and sheep.

    Jan P. M. Langeveld;Jeng-Jie Wang;Dick F. M. Van de Wiel;Giles C. Shih

  • Molecular Discrimination of Atypical Bovine Spongiform Encephalopathy Strains from a Geographical Region Spanning a Wide Area in Europe

    Jorg G. Jacobs;Jan P. M. Langeveld;Anne-Gaëlle Biacabe;Pier-Luigi Acutis

  • First peptide vaccine providing protection against viral infection in the target animal: studies of canine parvovirus in dogs.

    J. P. M. Langeveld;J. I. Casal;A. D. M. E. Osterhaus;E. Cortes

  • Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics.

    Ignazio Cali;Rudolph Castellani;Amer Alshekhlee;Yvonne Cohen

  • Oral immunisation of naive and primed animals with transgenic potato tubers expressing LT-B

    T.G.M Lauterslager;D.E.A Florack;T.J van der Wal;J.W Molthoff

  • Scrapie-associated prion protein in the gastro-intestinal tract of sheep with natural scrapie.

    L.J.M. van Keulen;B.E.C. Schreuder;M.E.W. Vromans;J.P.M. Langeveld

  • Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease.

    Helen M. Yull;Diane L. Ritchie;Jan P.M. Langeveld;Fred G. van Zijderveld

  • Effect of different baculovirus inactivation procedures on the integrity and immunogenicity of porcine parvovirus-like particles.

    Paloma Rueda;Jesús Fominaya;Jan P.M Langeveld;Christianne Bruschke

  • Discrimination between Scrapie and Bovine Spongiform Encephalopathy in Sheep by Molecular Size, Immunoreactivity, and Glycoprofile of Prion Protein

    C. M. A. Thuring;J. H. F. Erkens;J. G. Jacobs;A. Bossers

  • State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology.

    G. Vaccari;C.H. Panagiotidis;C. Acin;S. Peletto

  • Rapid and discriminatory diagnosis of scrapie and BSE in retro-pharyngeal lymph nodes of sheep

    Jan P M Langeveld;Jorg G Jacobs;Jo H F Erkens;Alex Bossers

  • A novel recombinant virus-like particle vaccine for prevention of porcine parvovirus-induced reproductive failure.

    Adriaan F.G. Antonis;Christianne J.M. Bruschke;Paloma Rueda;Luis Maranga

  • Immunohistochemical features of PrP(d) accumulation in natural and experimental goat transmissible spongiform encephalopathies.

    M. Jeffrey;S. Martin;L. González;J. Foster

Frequent Co-Authors

Rob H. Meloen
Rob H. Meloen Pepscan (Netherlands)
Martin H. Groschup
Martin H. Groschup Friedrich-Loeffler-Institut
Olivier Andreoletti
Olivier Andreoletti École Nationale Vétérinaire de Toulouse
Wilfred Goldmann
Wilfred Goldmann University of Edinburgh
Piero Parchi
Piero Parchi University of Bologna
Mark Head
Mark Head University of Edinburgh
Pierluigi Gambetti
Pierluigi Gambetti Case Western Reserve University
J. Ignacio Casal
J. Ignacio Casal Spanish National Research Council
Robert B. Petersen
Robert B. Petersen Case Western Reserve University
James W. Ironside
James W. Ironside University of Edinburgh

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