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Genetics

D-Index
41
Citations
7129
World Ranking
4327
National Ranking
491

Overview

Wilfred Goldmann is affiliated with the University of Edinburgh in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Nursing, and Neuroscience. Within these areas, their subfields of study include Molecular Biology, Neurology, and Nutrition and Dietetics.

Their work focuses on topics such as Prion Diseases and Protein Misfolding, Trace Elements in Health, Neurological Diseases and Metabolism, and Amyotrophic Lateral Sclerosis Research. These thematic interests highlight a multidisciplinary approach bridging molecular mechanisms and clinical implications.

Recent publications by Wilfred Goldmann include the following papers:

  • Caprine PRNP polymorphisms N146S and Q222K are associated with proteolytic cleavage of PrPC, 2021, Genetics Selection Evolution
  • BSE can propagate in sheep co-infected or pre-infected with scrapie, 2021, Scientific Reports
  • Experimental Bovine Spongiform Encephalopathy in Squirrel Monkeys: The Same Complex Proteinopathy Appearing after Very Different Incubation Times, 2022, Pathogens

Their research contributions appear in journals such as Genetics Selection Evolution, Scientific Reports, and Pathogens, indicating a publication record across diverse scientific venues.

Frequent co-authors collaborating with Wilfred Goldmann include:

  • Paula Stewart
  • Sally A. Madsen-Bouterse
  • Helen Williamson
  • David A. Schneider
  • Angela Chong

The combination of publication topics and collaborative relationships outlines an active engagement with research groups focused on prion diseases and related molecular biology fields. The clinical and biochemical overlap in their work further extends into studies involving neurological disease and protein misfolding.

Best Publications

  • PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie

    Wilfred Goldmann;Nora Hunter;Grace Smith;James Foster

  • Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes

    Nora Hunter;Jim Foster;Wilfred Goldmann;M. J. Stear

  • Atypical/Nor98 scrapie: properties of the agent, genetics, and epidemiology

    Unknown

  • Different forms of the bovine PrP gene have five or six copies of a short, G-C-rich element within the protein-coding exon.

    Wilfred Goldmann;Nora Hunter;Trevor Martin;Michael Dawson

  • The genetics of scrapie in sheep and goats.

    M Baylis;Wilfred Goldmann

  • Natural scrapie and PrP genotype: case-control studies in British sheep.

    N. Hunter;W. Goldmann;J. D. Foster;D. Cairns

  • PrP genetics in ruminant transmissible spongiform encephalopathies.

    Unknown

  • Novel polymorphisms in the caprine PrP gene: a codon 142 mutation associated with scrapie incubation period.

    Wilfred Goldmann;Trevor Martin;James Foster;Steve Hughes

  • Clinical signs, histopathology and genetics of experimental transmission of BSE and natural scrapie to sheep and goats.

    J. D. Foster;D. Parnham;A. Chong;W. Goldmann

  • The association of a codon 136 PrP gene variant with the occurrence of natural scrapie.

    Nora Hunter;Wilfred Goldmann;G Smith;J Hope

  • Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene.

    Wilfred Goldmann;Nora Hunter;Grace Benson;James D. Foster

  • Is scrapie solely a genetic disease

    Nora Hunter;D Cairns;Jim Foster;G Smith

  • Frequencies of PrP gene variants in healthy cattle and cattle with BSE in Scotland

    Nora Hunter;Wilfred Goldmann;G Smith;J Hope

  • State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology.

    G. Vaccari;C.H. Panagiotidis;C. Acin;S. Peletto

  • Prion protein gene polymorphisms in healthy and scrapie-affected Spanish sheep.

    Unknown

  • Ovine infection with the agents of scrapie (CH1641 isolate) and bovine spongiform encephalopathy: immunochemical similarities can be resolved by immunohistochemistry.

    M. Jeffrey;L. González;A. Chong;J. Foster

  • Frequencies of PrP gene haplotypes in British sheep flocks and the implications for breeding programmes.

    Wilfred Goldmann;M Baylis;C Chihota;E Stevenson

  • The shortest known prion protein gene allele occurs in goats, has only three octapeptide repeats and is non-pathogenic

    Wilfred Goldmann;Angela Chong;James Foster;James Hope

  • Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom

    Wilfred Goldmann;Kelly Ryan;Paula Stewart;David Parnham

  • Ovine prion protein variant A136R154L168Q171 increases resistance to experimental challenge with bovine spongiform encephalopathy agent

    Wilfred Goldmann;Fiona Houston;Paula Stewart;Matteo Perucchini

Frequent Co-Authors

Nora Hunter
Nora Hunter University of Edinburgh
Olivier Andreoletti
Olivier Andreoletti École Nationale Vétérinaire de Toulouse
Lorenzo González
Lorenzo González Animal and Plant Health Agency
Martin H. Groschup
Martin H. Groschup Friedrich-Loeffler-Institut
James Hope
James Hope One Health
Jan P. M. Langeveld
Jan P. M. Langeveld Wageningen University & Research
Martin Jeffrey
Martin Jeffrey Animal and Plant Health Agency
Matthew Baylis
Matthew Baylis University of Liverpool
Michael W. Miller
Michael W. Miller MSD (United States)
Jean Manson
Jean Manson University of Edinburgh

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