World's Best Scientists 2026 revealed!
Award Badge
Molecular Biology
Canada
2026

D-Index & Metrics

Molecular Biology

D-Index
106
Citations
40372
World Ranking
427
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Canada Leader Award
  • 2025 - Research.com Molecular Biology in Canada Leader Award
  • 2023 - Research.com Molecular Biology in Canada Leader Award
  • 2018 - Fellow of the Royal Society of Canada Academy of Science

Overview

Shoukat Dedhar is affiliated with the University of British Columbia in Canada. Their research spans several domains mainly within Biochemistry, Genetics and Molecular Biology, and Medicine. The focus includes Molecular Biology, Oncology, Cancer Research, Immunology, and Organic Chemistry.

Among their recent publications are works addressing cellular and molecular mechanisms related to cancer and biochemistry. Notable papers include:

  • Guidelines and definitions for research on epithelial-mesenchymal transition, 2020, Nature Reviews Molecular Cell Biology
  • A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors, 2020, American Journal of Clinical Oncology
  • Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment, 2020, Metabolites
  • Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors, 2021, Science Advances
  • Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer, 2020, Cell Reports Medicine

Key topics of research pursued by Dedhar include:

  • Enzyme function and inhibition
  • Cancer, Hypoxia, and Metabolism
  • Synthesis and Catalytic Reactions
  • Immune cells in cancer
  • Cell Adhesion Molecules Research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Polyamine Metabolism and Applications

Frequent co-authors collaborating with Dedhar comprise:

  • Paul C. McDonald
  • Shannon Awrey
  • Shawn C. Chafe
  • Wells S. Brown
  • Daniel J. Renouf

Dedhar's publications often appear in specialized venues including:

  • Cancer Research
  • Cancers
  • Journal of Thoracic Oncology
  • Nature Reviews Molecular Cell Biology
  • mAbs

Overall, Dedhar's scientific contribution primarily addresses the molecular underpinnings of cancer biology and therapeutic targeting strategies. Their interdisciplinary approach integrates biochemical mechanisms with clinical oncology insights.

In 2018, Dedhar was recognized as a Fellow of the Royal Society of Canada in the Academy of Science category.

Best Publications

  • The epithelial–mesenchymal transition: new insights in signaling, development, and disease

    Jonathan M. Lee;Shoukat Dedhar;Raghu Kalluri;Raghu Kalluri;Raghu Kalluri;Erik W. Thompson;Erik W. Thompson

  • Guidelines and definitions for research on epithelial–mesenchymal transition

    Jing Yang;Parker Antin;Geert Berx;Cédric Blanpain

  • Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

    Gregory E. Hannigan;Chungyee Leung-Hagesteijn;Linda Fitz-Gibbon;Marc G. Coppolino;Marc G. Coppolino

  • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

    Marc Delcommenne;Clara Tan;Virginia Gray;Laurent Rue

  • Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology

    Fei Wang;Valerie M. Weaver;Ole W. Petersen;Carolyn A. Larabell

  • Integrin-linked kinase: a cancer therapeutic target unique among its ILK

    Gregory E Hannigan;Armelle A Troussard;Shoukat Dedhar;Shoukat Dedhar

  • Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

    Yuanmei Lou;Paul C McDonald;Arusha Oloumi;Stephen K. Chia

  • Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343.

    Sujata Persad;Sarah Attwell;Virginia Gray;Nasrin Mawji

  • NGF-Induced Axon Growth Is Mediated by Localized Inactivation of GSK-3β and Functions of the Microtubule Plus End Binding Protein APC

    Feng Quan Zhou;Jiang Zhou;Shoukat Dedhar;Yao Hong Wu

  • Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes

    Chuanyue Wu;Shoukat Dedhar

  • Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells

    Sujata Persad;Sarah Attwell;Virginia Gray;Marc Delcommenne

  • Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways.

    Anton Novak;Shu-Chi Hsu;Chungyee Leung-Hagesteijn;Galina Radeva

  • Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.

    Sandra Guaita;Isabel Puig;Clara Francı́;Marta Garrido

  • Integrin cytoplasmic interactions and bidirectional transmembrane signalling

    Shoukat Dedhar;Gregory E Hannigan

  • Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis

    Fabio Pacchiano;Fabrizio Carta;Paul C. McDonald;Yuanmei Lou

  • Cytoskeletal rearrangements accompanying salmonella entry into epithelial cells.

    B. Brett Finlay;S. Ruschkowski;S. Dedhar

  • Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion

    Marc G. Coppolino;Michael J. Woodside;Nicolas Demaurex;Sergio Grinstein

  • Inhibition of nuclear hormone receptor activity by calreticulin

    Shoukat Dedhar;Paul S. Rennie;Mary Shago;Chung-Yee Leung Hagesteijn

  • Signaling through beta-catenin and Lef/Tcf.

    A Novak;S Dedhar

  • A cell surface receptor complex for collagen type I recognizes the Arg-Gly-Asp sequence.

    Shoukat Dedhar;Erkki Ruoslahti;Michael D. Pierschbacher

Frequent Co-Authors

Claudiu T. Supuran
Claudiu T. Supuran University of Florence
René St-Arnaud
René St-Arnaud Shriners Hospitals for Children - Erie
Marcel B. Bally
Marcel B. Bally University of British Columbia
Connie J. Eaves
Connie J. Eaves University of British Columbia
William J. Muller
William J. Muller McGill University
Chuanyue Wu
Chuanyue Wu University of Pittsburgh
Fabrizio Carta
Fabrizio Carta University of Florence
Xiaoyan Jiang
Xiaoyan Jiang University of British Columbia
Jean-Yves Winum
Jean-Yves Winum University of Montpellier
Karen A. Gelmon
Karen A. Gelmon University of British Columbia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

The field of Molecular Biology opens doors to diverse career opportunities and related academic pathways. Many students look to expand their knowledge with supplemental online degrees that strengthen their interdisciplinary skills. For example, programs such as an accelerated human services degree online can build a strong foundation in supporting public health and community services.

Some graduates also consider education-based roles. Exploring “what is an slp in education” offers insights into careers such as Speech-Language Pathologist, which share transferrable skills in scientific analysis and communication.

Technical expertise remains crucial. Completing an architect degree online or an online degree mathematics provides a strong analytical and problem-solving background relevant to Molecular Biology research, data analysis, or biotech roles.

Exploring these online degree options and related career pathways can help you tailor your educational journey and maximize your opportunities within and beyond Molecular Biology.

Best Scientists Citing Shoukat Dedhar

Trending Scientists