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Biology and Biochemistry

D-Index
48
Citations
17553
World Ranking
18188
National Ranking
635

Overview

Xiaoyan Jiang is affiliated with the University of British Columbia in Canada and has a research focus primarily in Medicine and Biochemistry, Genetics, and Molecular Biology. Their work extensively covers subfields such as Molecular Biology, Hematology, Genetics, Neurology, and Cancer Research.

The research topics explored by Jiang include:

  • Chronic Myeloid Leukemia Treatments
  • RNA Interference and Gene Delivery
  • Acute Myeloid Leukemia Research
  • Chronic Lymphocytic Leukemia Research
  • Cancer-related gene regulation
  • MicroRNA in disease regulation
  • Wnt/β-catenin signaling in development and cancer

Key recent publications authored or co-authored by Jiang feature:

  • Deep Learning for Medical Image-Based Cancer Diagnosis, 2023, Cancers
  • Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study, 2022, Cell Research
  • The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML, 2020, Blood
  • Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors, 2020, Cell stem cell
  • Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia, 2021, Blood

Jiang has frequently published in the following venues:

  • Blood
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Leukemia
  • Applied Intelligence
  • PubMed

Collaborations have been established with several co-authors including:

  • Andrew Wu
  • Katharina Rothe
  • Donna L. Forrest
  • Connie J. Eaves
  • Hasan Uludağ

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia.

    Tessa Holyoake;Xiaoyan Jiang;Connie Eaves;Allen Eaves

  • Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies.

    X Jiang;X Jiang;Y Zhao;C Smith;C Smith;M Gasparetto

  • Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia

    Xiaoyan Jiang;Angel Lopez;Tessa Holyoake;Allen Eaves

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Stable Suppression of a Novel Oncogene, AHI-1, in Human Cutaneous T-Cell Leukemia Cells Normalizes Its Transforming Activity In Vitro and In Vivo and Aberrant Expression of AHI-1 Is Also Present in Leukemic Sezary Cells from Patients with Sezary Syndrome.

    Ashley Ringrose;Youwen Zhou;Emily Pang;Ann E.-J. Lin

  • Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3

    Tessa L. Holyoake;Xiaoyan Jiang;Xiaoyan Jiang;Heather G. Jorgensen;Heather G. Jorgensen;Susan Graham;Susan Graham

  • A novel role of phospholipase A2 in mediating spinal cord secondary injury.

    Nai Kui Liu;Yi Ping Zhang;William Lee Titsworth;Xiaoyan Jiang

  • The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells.

    Katharina Rothe;Hanyang Lin;Hanyang Lin;Kevin B. L. Lin;Amy Leung

  • Identification and molecular typing of Streptococcus agalactiae isolated from pond-cultured tilapia in China

    Xing Ye;Jiong Li;Maixin Lu;Guocheng Deng

  • Instability of BCR–ABL Gene in Primary and Cultured Chronic Myeloid Leukemia Stem Cells

    Xiaoyan Jiang;Kyi Min Saw;Allen Eaves;Connie Eaves

  • Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia

    TL Holyoake;X Jiang;MW Drummond;AC Eaves;AC Eaves

  • Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease

    W Eisterer;X Jiang;O Christ;H Glimm;H Glimm

  • Expression and function of miRNA in postoperative radiotherapy sensitive and resistant patients of non-small cell lung cancer

    Xiao-Chun Wang;Li-Qing Du;Li-Li Tian;Hai-Liang Wu

  • Insights into the stem cells of chronic myeloid leukemia

    I Sloma;X Jiang;A C Eaves;C J Eaves

  • Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocyte-colony stimulating factor in vitro promotes their elimination by imatinib mesylate.

    Heather G. Jørgensen;Mhairi Copland;Elaine K. Allan;Xiaoyan Jiang

  • Platelet-derived growth factor-AA mediates oligodendrocyte lineage differentiation through activation of extracellular signal-regulated kinase signaling pathway.

    J.-G. Hu;S.-L. Fu;Y.-X. Wang;Y. Li

  • Characterization of a ranavirus isolated from cultured largemouth bass (Micropterus salmoides) in China

    Guocheng Deng;Shengjie Li;Jun Xie;Junjie Bai

  • B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies

    Gang Xiao;Lai N. Chan;Lars Klemm;Daniel Braas

Frequent Co-Authors

Connie J. Eaves
Connie J. Eaves University of British Columbia
Allen C. Eaves
Allen C. Eaves Stemcell Technologies
Tessa L. Holyoake
Tessa L. Holyoake University of Glasgow
Hasan Uludağ
Hasan Uludağ University of Alberta
Ali G. Turhan
Ali G. Turhan University of Paris-Saclay
Xiao Ming Xu
Xiao Ming Xu Indiana University
Inanc Birol
Inanc Birol University of British Columbia
R. Keith Humphries
R. Keith Humphries University of British Columbia
Evelina Gatti
Evelina Gatti Aix-Marseille University
Dixie L. Mager
Dixie L. Mager University of British Columbia

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