Allen C. Eaves

Overview

Best Publications

• Characterization and Partial Purification of Human Marrow Cells Capable of Initiating Long-Term Hematopoiesis In Vitro

  Heather J. Sutherland;Connie J. Eaves;Allen C. Eaves;Wieslawa Dragowska

  894
  Citations

• Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers.

  Heather J. Sutherland;Peter M. Lansdorp;Don H. Henkelman;Allen C. Eaves

  891
  Citations

• Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia.

  Tessa Holyoake;Xiaoyan Jiang;Connie Eaves;Allen Eaves

  655
  Citations

• Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy.

  S J Szilvassy;R K Humphries;P M Lansdorp;A C Eaves

  572
  Citations

• Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies.

  X Jiang;X Jiang;Y Zhao;C Smith;C Smith;M Gasparetto

  451
  Citations

• Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer.

  CJ Eaves;JD Cashman;RJ Kay;GJ Dougherty

  423
  Citations

• Enzymatic treatment of long-term human marrow cultures reveals the preferential location of primitive hemopoietic progenitors in the adherent layer

  L Coulombel;AC Eaves;CJ Eaves

  415
  Citations

• Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic properties.

  Connie J. Gregory;Allen C. Eaves

  381
  Citations

• Human marrow cells capable of erythropoietic differentiation in vitro: definition of three erythroid colony responses.

  Connie J. Gregory;Allen C. Eaves

  380
  Citations

• Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera

  Connie J. Eaves;Allen C. Eaves

  354
  Citations

• Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta

  Johanne D. Cashman;Allen C. Eaves;Elaine W. Raines;Russell Ross

  337
  Citations

• Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia

  Xiaoyan Jiang;Angel Lopez;Tessa Holyoake;Allen Eaves

  304
  Citations

• Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis.

  Christian Sirard;Tsvee Lapidot;Josef Vormoor;Jody D. Cashman

  261
  Citations

• Enumeration of neural stem and progenitor cells in the neural colony-forming cell assay.

  Sharon A. Louis;Rodney L. Rietze;Loic Deleyrolle;Ravenska E. Wagey

  260
  Citations

• Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometry

  Tim H. Brümmendorf;Tessa L. Holyoake;Nathalie Rufer;Michael J. Barnett

  259
  Citations

• High level engraftment of NOD/SCID mice by primitive normal and leukemic hematopoietic cells from patients with chronic myeloid leukemia in chronic phase

  J.C.Y. Wang;T. Lapidot;J.D. Cashman;M. Doedens

  246
  Citations

• Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells.

  Allen C. Eaves;Johanne D. Cashman;Louis A. Gaboury;Dagmar K. Kalousek

  244
  Citations

• Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level.

  C Udomsakdi;C J Eaves;B Swolin;D S Reid

  237
  Citations

• Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3

  Tessa L. Holyoake;Xiaoyan Jiang;Xiaoyan Jiang;Heather G. Jorgensen;Heather G. Jorgensen;Susan Graham;Susan Graham

  234
  Citations

• Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture.

  Barnett Mj;Eaves Cj;Phillips Gl;Kalousek Dk

  206
  Citations