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Biology and Biochemistry

D-Index
60
Citations
31146
World Ranking
11655
National Ranking
229

Overview

Eduard Batlle is affiliated with the Institució Catalana de Recerca i Estudis Avançats in Spain. Their research spans multiple fields, primarily Medicine, with significant contributions to Biochemistry, Genetics and Molecular Biology. Batlle's work focuses on Oncology, Molecular Biology, Cell Biology, Biomedical Engineering, and Immunology.

The scientist's main research topics include Cancer Cells and Metastasis, Cancer Immunotherapy and Biomarkers, Colorectal Cancer Treatments and Studies, Cellular Mechanics and Interactions, 3D Printing in Biomedical Research, Single-cell and Spatial Transcriptomics, and Genetic Factors in Colorectal Cancer.

Eduard Batlle has published several papers, including the following recent works:

  • Benchmarking single-cell RNA-sequencing protocols for cell atlas projects, 2020, Nature Biotechnology
  • Overcoming TGFβ-mediated immune evasion in cancer, 2021, Nature Reviews Cancer
  • Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration, 2021, Nature Cell Biology
  • Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells, 2022, Nature
  • A single-cell tumor immune atlas for precision oncology, 2021, Genome Research

The frequent co-authors collaborating with Batlle include:

  • Xavier Hernando-Momblona
  • Daniele V. F. Tauriello
  • Elena Sancho
  • Adrià Cañellas-Socias
  • Holger Heyn

Batlle has published multiple papers in various scientific venues, with the most frequent publication platforms being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Reviews Cancer
  • Nature Cancer
  • Cancer Research

Best Publications

  • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells.

    Eduard Batlle;Elena Sancho;Clara Francí;David Domínguez

  • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.

    Marc van de Wetering;Elena Sancho;Cornelis Verweij;Wim de Lau

  • Cancer stem cells revisited

    Eduard Batlle;Hans Clevers

  • TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

    Daniele V. F. Tauriello;Sergio Palomo-Ponce;Diana Stork;Antonio Berenguer-Llergo

  • Transforming Growth Factor-β Signaling in Immunity and Cancer.

    Eduard Batlle;Joan Massagué

  • β-Catenin and TCF Mediate Cell Positioning in the Intestinal Epithelium by Controlling the Expression of EphB/EphrinB

    Eduard Batlle;Jeffrey T. Henderson;Harry Beghtel;Maaike M.W. van den Born

  • Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

    Alexandre Calon;Elisa Espinet;Sergio Palomo-Ponce;Daniele V.F. Tauriello

  • Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

    Alexandre Calon;Enza Lonardo;Antonio Berenguer-Llergo;Elisa Espinet

  • The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

    Anna Merlos-Suárez;Francisco M. Barriga;Peter Jung;Mar Iglesias

  • Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.

    Owen J. Sansom;Karen Reed;Anthony Joseph Hayes;Heather Ireland

  • Isolation and in vitro expansion of human colonic stem cells

    Peter Jung;Toshiro Sato;Toshiro Sato;Anna Merlos-Suárez;Francisco M Barriga

  • Metastatic stem cells: sources, niches, and vital pathways.

    Thordur Oskarsson;Eduard Batlle;Joan Massagué;Joan Massagué

  • Signaling pathways in intestinal development and cancer.

    Elena Sancho;Eduard Batlle;Hans Clevers

  • Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.

    Sandra Guaita;Isabel Puig;Clara Francı́;Marta Garrido

  • Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD

    Annette F Baas;Jeroen Kuipers;Nicole N van der Wel;Eduard Batlle

  • EphB receptor activity suppresses colorectal cancer progression

    Eduard Batlle;Julinor Bacani;Harry Begthel;Suzanne Jonkeer

  • Role of tRNA modifications in human diseases.

    Adrian Gabriel Torres;Eduard Batlle;Lluis Ribas de Pouplana

  • Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

    Elisabetta Mereu;Atefeh Lafzi;Catia Moutinho;Christoph Ziegenhain

  • The circadian molecular clock creates epidermal stem cell heterogeneity

    Peggy Janich;Gloria Pascual;Anna Merlos-Suárez;Eduard Batlle

  • TGF-beta in CAF-mediated tumor growth and metastasis

    A. Calon;D.V.F. Tauriello;E. Batlle

Frequent Co-Authors

Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Joan Massagué
Joan Massagué Memorial Sloan Kettering Cancer Center
Tony Pawson
Tony Pawson University of Toronto
Holger Heyn
Holger Heyn Pompeu Fabra University
Antonio García de Herreros
Antonio García de Herreros Pompeu Fabra University
Steven T. Pals
Steven T. Pals University of Amsterdam
Ivo Gut
Ivo Gut Centro Nacional de Análisis Genómico
Aviv Regev
Aviv Regev Genentech
Oliver Stegle
Oliver Stegle German Cancer Research Center
Elena Martínez
Elena Martínez Institute for Bioengineering of Catalonia

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