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Chemistry

D-Index
74
Citations
22612
World Ranking
4617
National Ranking
1456

Biology and Biochemistry

D-Index
74
Citations
22762
World Ranking
5528
National Ranking
2626

Research.com Recognitions

  • 2017 - Fellow of the American Academy of Microbiology Microbial Physiology and Metabolism

Overview

Robert P. Hausinger is affiliated with Michigan State University in the United States. Their research spans several fields, with a primary focus on biochemistry, genetics, and molecular biology, contributing to 54 publications in these areas. Hausinger's work also includes substantial output in materials science, particularly materials chemistry and inorganic chemistry, with a combined total of 32 publications. The scientist's subfields of study further highlight expertise in molecular biology, biochemistry, renewable energy, sustainability and the environment.

Hausinger's research topics concentrate on enzyme structure and function, metal-catalyzed oxygenation mechanisms, and porphyrin metabolism and disorders. Additional key areas include biochemical and molecular research, microbial metabolism and enzyme function, amino acid enzymes and metabolism, and metalloenzymes with iron-sulfur proteins.

The scientist has published in several well-known academic venues. Frequent publication venues include:

  • Biochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • ACS Catalysis
  • Critical Reviews in Biochemistry and Molecular Biology

Robert P. Hausinger has collaborated regularly with a number of researchers, including Jian Hu, Shramana Chatterjee, Santhosh Gatreddi, Christo Christov, and Benoît Desguin.

Recent papers authored or coauthored by Hausinger include:

  • Bile salt hydrolase acyltransferase activity expands bile acid diversity, 2024, Nature
  • Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function, 2020, Journal of Biological Chemistry
  • Atomic and Electronic Structure Determinants Distinguish between Ethylene Formation and l-Arginine Hydroxylation Reaction Mechanisms in the Ethylene-Forming Enzyme, 2021, ACS Catalysis
  • Biological Pincer Complexes, 2020, ChemCatChem
  • Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases, 2020, Scientific Reports

Hausinger was recognized as a Fellow of the American Academy of Microbiology in 2017 for contributions in microbial physiology and metabolism.

Best Publications

  • Microbial ureases: significance, regulation, and molecular characterization.

    H. L T Mobley;R. P. Hausinger

  • Molecular biology of microbial ureases.

    H. L T Mobley;M. D. Island;R. P. Hausinger

  • FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes.

    Robert P. Hausinger

  • The crystal structure of urease from Klebsiella aerogenes

    E Jabri;MB Carr;RP Hausinger;PA Karplus

  • Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

    Sarah C. Trewick;Timothy F. Henshaw;Robert P. Hausinger;Tomas Lindahl

  • Nickel uptake and utilization by microorganisms

    Scott B. Mulrooney;Robert P. Hausinger

  • 70 Years of Crystalline Urease: What Have We Learned?

    P. Andrew Karplus and;Matthew A. Pearson;Robert P. Hausinger

  • Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent Oxygenases

    Salette Martinez;Robert P. Hausinger

  • Nickel utilization by microorganisms.

    R P Hausinger

  • Mechanisms of nickel toxicity in microorganisms

    Lee Macomber;Robert P. Hausinger

  • Nickel-dependent metalloenzymes.

    Jodi L. Boer;Scott B. Mulrooney;Robert P. Hausinger

  • Direct Detection of Oxygen Intermediates in the Non-Heme Fe Enzyme Taurine/α-Ketoglutarate Dioxygenase

    Denis A. Proshlyakov;Timothy F. Henshaw;Greta R. Monterosso;Matthew J. Ryle

  • X-Ray Crystal Structure of Escherichia Coli Taurine/Alpha-Ketoglutarate Dioxygenase Complexed to Ferrous Iron and Substrates

    Jonathan M. Elkins;Matthew J. Ryle;Ian J. Clifton;Julie C. Dunning Hotopp

  • Non-heme iron oxygenases.

    Matthew J Ryle;Robert P Hausinger

  • Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.

    M.A Pearson;L.O Michel;R.P Hausinger;P.A. Karplus

  • Purification and characterization of 2,4-dichlorophenoxyacetate/alpha-ketoglutarate dioxygenase.

    Fumiyasu Fukumori;Robert P. Hausinger

  • Sequence of the Klebsiella aerogenes urease genes and evidence for accessory proteins facilitating nickel incorporation

    S B Mulrooney;R P Hausinger

  • Biochemistry of nickel

    Robert P. Hausinger

  • Interplay of metal ions and urease.

    Eric L. Carter;Nicholas Flugga;Jodi L. Boer;Scott B. Mulrooney

  • Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis.

    Mann Hyung Lee;S. B. Mulrooney;M. J. Renner;Y. Markowicz

  • Alcaligenes eutrophus JMP134 "2,4-dichlorophenoxyacetate monooxygenase" is an alpha-ketoglutarate-dependent dioxygenase.

    F Fukumori;R P Hausinger

Frequent Co-Authors

Robert A. Scott
Robert A. Scott University of Cambridge
Lawrence Que
Lawrence Que University of Minnesota
Pascal Hols
Pascal Hols Université Catholique de Louvain
Deborah A. Hogan
Deborah A. Hogan Dartmouth College
James B. Howard
James B. Howard University of Minnesota
Christopher T. Walsh
Christopher T. Walsh Stanford University
Anastassis Perrakis
Anastassis Perrakis Antoni van Leeuwenhoek Hospital
P. Andrew Karplus
P. Andrew Karplus Oregon State University
Harry L. T. Mobley
Harry L. T. Mobley University of Michigan–Ann Arbor

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