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Chemistry

D-Index
76
Citations
18459
World Ranking
4303
National Ranking
1355

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

J. Martin Bollinger is affiliated with Pennsylvania State University in the United States. Their research spans biochemistry, genetics, and molecular biology, as well as chemistry, with a strong focus on molecular biology and inorganic chemistry.

The primary topics in Bollinger's research include:

  • Metal-Catalyzed Oxygenation Mechanisms
  • Porphyrin Metabolism and Disorders
  • Metalloenzymes and iron-sulfur proteins
  • Microbial metabolism and enzyme function
  • Heme Oxygenase-1 and Carbon Monoxide
  • Hemoglobin structure and function
  • Metal complexes synthesis and properties

Bollinger's recent publications highlight research into iron-sulfur cofactors, enzymatic intermediates, and biosynthesis mechanisms. Among the notable papers are:

  • Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets, 2021, Science
  • A Peroxodiiron(III/III) Intermediate Mediating Both N-Hydroxylation Steps in Biosynthesis of the N-Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF, 2020, Journal of the American Chemical Society
  • Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the N-nitrosourea-producing enzyme SznF, 2021, Proceedings of the National Academy of Sciences
  • Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase, 2020, Nature Communications
  • Nuclear Resonance Vibrational Spectroscopic Definition of the Facial Triad FeIV=O Intermediate in Taurine Dioxygenase: Evaluation of Structural Contributions to Hydrogen Atom Abstraction, 2020, Journal of the American Chemical Society

The scientist's frequent collaborators include:

  • Carsten Krebs (27 joint publications)
  • Amie K. Boal (16 joint publications)
  • Debangsu Sil (10 joint publications)
  • Molly J. McBride (10 joint publications)
  • Jeffrey W. Slater (10 joint publications)

Bollinger has published multiple articles in journals with recurring appearances such as:

  • Biochemistry (8 publications)
  • Journal of the American Chemical Society (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)
  • Proceedings of the National Academy of Sciences (3 publications)
  • Science (2 publications)

In recognition of their work, Bollinger was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • Non-heme Fe(IV)-oxo intermediates.

    Carsten Krebs;Danica Galonić Fujimori;Christopher T. Walsh;J. Martin Bollinger

  • The First Direct Characterization of a High-Valent Iron Intermediate in the Reaction of an α-Ketoglutarate-Dependent Dioxygenase: A High-Spin Fe(IV) Complex in Taurine/α-Ketoglutarate Dioxygenase (TauD) from Escherichia coli†

    John C. Price;Eric W. Barr;Bhramara Tirupati;J. Martin Bollinger

  • Evidence for Hydrogen Abstraction from C1 of Taurine by the High-Spin Fe(IV) Intermediate Detected during Oxygen Activation by Taurine:α -Ketoglutarate Dioxygenase (TauD)

    John C. Price;Eric W. Barr;Timothy E. Glass;Carsten Krebs

  • Mechanism of assembly of the tyrosyl radical-dinuclear iron cluster cofactor of ribonucleotide reductase.

    J. M. Bollinger;D. E. Edmondson;B. H. Huynh;J. Filley

  • Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase

    Lee M. Hoffart;Eric W. Barr;Robert B. Guyer;J. Martin Bollinger

  • Two interconverting Fe( IV ) intermediates in aliphatic chlorination by the halogenase CytC3

    Danica P Galonić;Eric W Barr;Christopher T Walsh;J Martin Bollinger

  • EXAFS Spectroscopic Evidence for an FeO Unit in the Fe(IV) Intermediate Observed during Oxygen Activation by Taurine:α-Ketoglutarate Dioxygenase

    Pamela J. Riggs-Gelasco;John C. Price;Robert B. Guyer;Jessica H. Brehm

  • 2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase.

    C. H. Baker;J. Banzon;J. M. Bollinger;J. Stubbe

  • A Model for the Role of Multiple Cysteine Residues Involved in Ribonucleotide Reduction: Amazing and Still Confusing

    S. S. Mao;T. P. Holler;G. X. Yu;J. M. Bollinger

  • Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2

    Megan L. Matthews;Courtney M. Krest;Eric W. Barr;Frédéric H. Vaillancourt

  • Spectroscopic and Computational Evaluation of the Structure of the High-Spin Fe(IV)-Oxo Intermediates in Taurine: α-Ketoglutarate Dioxygenase from Escherichia coli and Its His99Ala Ligand Variant

    Sebastian Sinnecker;Nina Svensen;Eric W. Barr;Shengfa Ye

  • Elucidation of the Fe( iv )=O intermediate in the catalytic cycle of the halogenase SyrB2

    Shaun D. Wong;Martin Srnec;Megan L. Matthews;Megan L. Matthews;Lei V. Liu

  • Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2

    Megan L. Matthews;Christopher S. Neumann;Linde A. Miles;Tyler L. Grove

  • Binuclear [2Fe-2S] Clusters in the Escherichia coli SoxR Protein and Role of the Metal Centers in Transcription

    Hidalgo E;Bollinger Jm;Bradley Tm;Walsh Ct

  • Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactor of E. Coli Ribonucleotide Reductase: 1. Moessbauer Characterization of the Diferric Radical Precursor

    Natarajan Ravi;J. Martin Bollinger;Boi Hanh Huynh;JoAnne Stubbe

  • A Manganese(IV)/Iron(III) Cofactor in Chlamydia trachomatis Ribonucleotide Reductase

    Wei Jiang;Danny Yun;Lana Saleh;Eric W. Barr

  • Direct spectroscopic evidence for a high-spin Fe(IV) intermediate in tyrosine hydroxylase.

    Bekir E. Eser;Eric W. Barr;Patrick A. Frantom;Lana Saleh

  • Kinetic Dissection of the Catalytic Mechanism of Taurine:α-Ketoglutarate Dioxygenase (TauD) from Escherichia coli†

    John C. Price;Eric W. Barr;Lee M. Hoffart;Carsten Krebs

  • Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactorof E. coli Ribonucleotide Reductase. 3. Kinetics of the Limiting Fe2+ Reaction by Optical, EPR, and Moessbauer Spectroscopies

    J. Martin Bollinger;Wing Hang Tong;Natarajan Ravi;Boi Hahn Huynh

  • Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

    Franklin D Fuller;Sheraz Gul;Ruchira Chatterjee;E Sethe Burgie

  • O2 Activation by Non-Heme Diiron Proteins: Identification of a Symmetric μ-1,2-Peroxide in a Mutant of Ribonucleotide Reductase†

    Pierre Moënne-Loccoz;Jeffrey Baldwin;Brenda A. Ley;Thomas M. Loehr

Frequent Co-Authors

Carsten Krebs
Carsten Krebs Pennsylvania State University
George A. Olah
George A. Olah University of Southern California
Edward I. Solomon
Edward I. Solomon Stanford University
Christopher T. Walsh
Christopher T. Walsh Stanford University
Squire J. Booker
Squire J. Booker Pennsylvania State University
Amy C. Rosenzweig
Amy C. Rosenzweig Northwestern University
Shengfa Ye
Shengfa Ye Sun Yat-sen University
Neil L. Kelleher
Neil L. Kelleher Northwestern University
Paul F. Fitzpatrick
Paul F. Fitzpatrick The University of Texas Health Science Center at San Antonio

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