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Immunology

D-Index
59
Citations
13243
World Ranking
3420
National Ranking
1588

Research.com Recognitions

  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ruth M. Ruprecht is affiliated with the Texas Biomedical Research Institute in the United States. Their research primarily spans the fields of immunology and microbiology, with significant contributions in medicine. The subfields of study include immunology, virology, epidemiology, radiology, nuclear medicine and imaging, and genetics.

The scientist's work focuses on several key topics, including:

  • HIV Research and Treatment
  • Cytomegalovirus and herpesvirus research
  • Immune Cell Function and Interaction
  • Herpesvirus Infections and Treatments
  • Immunotherapy and Immune Responses
  • Monoclonal and Polyclonal Antibodies Research
  • T-cell and B-cell Immunology

Ruprecht has published extensively in a range of scientific venues. Frequent publication outlets include:

  • Frontiers in Immunology
  • PLoS Pathogens
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Immunology
  • Science Translational Medicine

Recent publications highlight contributions to vaccine development, immune function, and viral infections. Selected papers are:

  • "A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity," 2021, Science Immunology
  • "Immunoglobulin M: An Ancient Antiviral Weapon - Rediscovered," 2020, Frontiers in Immunology
  • "Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity," 2022, Science Translational Medicine
  • "Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates," 2021, Biomaterials
  • "Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type," 2020, PLoS Pathogens

The scientist collaborates frequently with several researchers, including:

  • Siqi Gong
  • François Villinger
  • Kenneth A. Rogers
  • Sidath C. Kumarapperuma
  • Roslyn A. Taylor

Recognition in their career includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2004.

Best Publications

  • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes.

    T. H. Finkel;G. Tudor-Williams;N. K. Banda;M. F. Cotton

  • Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection.

    Timothy W. Baba;Vladimir Liska;Regina Hofmann-Lehmann;Josef Vlasak

  • Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

    Timothy W. Baba;Yong Seok Jeong;Dominique Pennick;Rod Bronson

  • Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques

    Timothy W. Baba;Timothy W. Baba;Vladimir Liska;Anis H. Khimani;Nancy B. Ray

  • Suppression of mouse viraemia and retroviral disease by 3'-azido-3'-deoxythymidine.

    Ruth M. Ruprecht;Luke G. O'Brien;Lucia D. Rossoni;Sandra Nusinoff-Lehrman

  • Inhibition of HIV-1 replication by an aqueous extract of Spirulina platensis (Arthrospira platensis).

    Seyoum Ayehunie;Amha Belay;Timothy W. Baba;Ruth M. Ruprecht

  • Sensitive and robust one-tube real-time reverse transcriptase-polymerase chain reaction to quantify SIV RNA load: comparison of one- versus two-enzyme systems.

    Regina Hofmann-Lehmann;Ryan K. Swenerton;Vladimir Liska;Christian M. Leutenegger

  • Complete Protection of Neonatal Rhesus Macaques against Oral Exposure to Pathogenic Simian-Human Immunodeficiency Virus by Human Anti-HIV Monoclonal Antibodies

    Flavia Ferrantelli;Robert A. Rasmussen;Kathleen A. Buckley;Pei-Lin Li

  • Postnatal Passive Immunization of Neonatal Macaques with a Triple Combination of Human Monoclonal Antibodies against Oral Simian-Human Immunodeficiency Virus Challenge

    Regina Hofmann-Lehmann;Josef Vlasak;Robert A. Rasmussen;Beverly A. Smith

  • Infection and AIDS in Adult Macaques After Nontraumatic Oral Exposure to Cell-Free SIV

    Timothy W. Baba;Anita M. Trichel;Li An;Vladimir Liska

  • Recent advances in the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination.

    Victoria R. Polonis;Bruce K. Brown;Andrew Rosa Borges;Susan Zolla-Pazner

  • Human Immunodeficiency Virus-1 Entry Into Purified Blood Dendritic Cells Through CC and CXC Chemokine Coreceptors

    Seyoum Ayehunie;Eduardo A. Garcia-Zepeda;James A. Hoxie;Richard Horuk

  • Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences.

    C A Rosen;W A Haseltine;J Lenz;R Ruprecht

  • Molecularly Cloned SHIV-1157ipd3N4: a Highly Replication- Competent, Mucosally Transmissible R5 Simian-Human Immunodeficiency Virus Encoding HIV Clade C env

    R. J. Song;A.-L. Chenine;R. A. Rasmussen;C. R. Ruprecht

  • Effect of CD8+ Lymphocyte Depletion on Virus Containment after Simian Immunodeficiency Virus SIVmac251 Challenge of Live Attenuated SIVmac239Δ3-Vaccinated Rhesus Macaques

    Jörn E. Schmitz;R. Paul Johnson;Harold M. McClure;Kelledy H. Manson

  • Alkylating agent resistance: in vitro studies with human cell lines

    Emil Frei;Carol A. Cucchi;Andre Rosowsky;Ramana Tantravahi

  • Pentoxifylline (trental) decreases the replication of the human immunodeficiency virus type 1 in human peripheral blood mononuclear cells and in cultured T cells

    Fatemeh Fazely;Bruce J. Dezube;Judy Allen-Ryan;Arthur B. Pardee

  • Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation.

    Regina Hofmann-Lehmann;Josef Vlasak;Alison L Williams;Agnès-Laurence Chenine

  • Live attenuated HIV vaccines: pitfalls and prospects.

    James B Whitney;Ruth M Ruprecht

  • A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.

    Murillo Silva;Yu Kato;Mariane B Melo;Ivy Phung

  • Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques.

    Flavia Ferrantelli;Regina Hofmann-Lehmann;Robert A. Rasmussen;Tao Wang

  • Neutralizing antibodies against HIV -- back in the major leagues?

    Flavia Ferrantelli;Ruth M Ruprecht

Frequent Co-Authors

David C. Montefiori
David C. Montefiori Duke University
Regina Hofmann-Lehmann
Regina Hofmann-Lehmann University of Zurich
Francois Villinger
Francois Villinger University of Louisiana at Lafayette
Lisa A. Cavacini
Lisa A. Cavacini University of Massachusetts Chan Medical School
Harold M. McClure
Harold M. McClure Emory University
Hermann Katinger
Hermann Katinger BOKU University
Charles Wood
Charles Wood University of Nebraska–Lincoln
Marshall R. Posner
Marshall R. Posner Icahn School of Medicine at Mount Sinai
Arthur B. Pardee
Arthur B. Pardee Harvard University
Bruce J. Dezube
Bruce J. Dezube Beth Israel Deaconess Medical Center

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