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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
9173
World Ranking
15225
National Ranking
597

Overview

David J. S. Hulmes is affiliated with Claude Bernard University Lyon 1 in France and works primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their research interests focus on molecular processes relevant to connective tissue disorders, TGF-β signaling pathways in diseases, and the role of Wnt/β-catenin signaling in development and cancer. Bone health and related treatments also constitute significant areas of their scientific inquiry.

Their work is distinguished by contributions to several interconnected fields, including:

  • Biochemistry, Genetics and Molecular Biology
  • Molecular Biology
  • Genetics
  • Oncology

The scientist has contributed to the understanding of connective tissue disorders and signaling mechanisms by studying the interactions and inhibitory mechanisms involving secreted frizzled related proteins and bone morphogenetic protein-1 (BMP-1). This includes exploration of how these proteins influence bone metabolism and development.

Recent publications from David J. S. Hulmes include:

  • Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1), 2022, Scientific Reports
  • Insights into the mechanism of inhibition of bone morphogenetic protein-1 (BMP-1) by the secreted frizzled related protein Sizzled, 2022, Research Square (Research Square)

Frequent collaborators in their research projects are:

  • Sandrine Vadon-Le Goff
  • Karl Harlos
  • Yuguang Zhao
  • Natacha Mariano
  • Cécile Bijakowski

The scientist has published work in venues such as:

  • Scientific Reports
  • Research Square (Research Square)

Best Publications

  • Building collagen molecules, fibrils, and suprafibrillar structures.

    David J.S. Hulmes

  • Analysis of the primary structure of collagen for the origins of molecular packing

    David J.S. Hulmes;David J.S. Hulmes;Andrew Miller;Andrew Miller;David A.D. Parry;David A.D. Parry;Karl A. Piez;Karl A. Piez

  • Radial packing, order, and disorder in collagen fibrils.

    D J Hulmes;Tim J Wess;D J Prockop;P Fratzl

  • Quasi-hexagonal molecular packing in collagen fibrils

    David J. S. Hulmes;David J. S. Hulmes;Andrew Miller

  • Collagen Diversity, Synthesis and Assembly

    D.J.S. Hulmes

  • Collagen XI Nucleates Self-assembly and Limits Lateral Growth of Cartilage Fibrils

    Ulrich K. Blaschke;Eric F. Eikenberry;David J.S. Hulmes;Hans-Joachim Galla

  • Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs

    M. R. Lang;G. W. Fiaux;M. Gillooly;J. A. Stewart

  • Orthogonal scaffold of magnetically aligned collagen lamellae for corneal stroma reconstruction

    Jim Torbet;Marilyne Malbouyres;Nicolas Builles;Virginie Justin

  • Collagen-mineral axial relationship in calcified turkey leg tendon by X-ray and neutron diffraction.

    Stephen W. White;David J. S. Hulmes;Andrew Miller;Peter A. Timmins

  • Lysyl Oxidase-like Protein from Bovine Aorta ISOLATION AND MATURATION TO AN ACTIVE FORM BY BONE MORPHOGENETIC PROTEIN-1

    Agnes Borel;Denise Eichenberger;Jean Farjanel;Efrat Kessler

  • The collagen superfamily--diverse structures and assemblies.

    Hulmes Dj

  • Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength

    Claudia Broder;Philipp Arnold;Sandrine Vadon-Le Goff;Moritz A. Konerding

  • BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling.

    Sandrine Vadon-Le Goff;David J.S. Hulmes;Catherine Moali

  • Electron microscopy shows periodic structure in collagen fibril cross sections.

    D J Hulmes;J C Jesior;A Miller;C Berthet-Colominas

  • Collagen polymorphism: Its origins in the amino acid sequence

    Barbara B. Doyle;David W.L. Hukins;David J.S. Hulmes;Andrew Miller

  • Interpretation of the meridional X-ray diffraction pattern from collagen fibres in terms of the known amino acid sequence.

    David J.S. Hulmes;Andrew Miller;Stephen W. White;Barbara Brodsky Doyle

  • Procollagen segment-long-spacing crystallites: their role in collagen fibrillogenesis.

    Romaine R. Bruns;David J. S. Hulmes;Stephen F. Therrien;Jerome Gross

  • Substrate-specific Modulation of a Multisubstrate Proteinase C-TERMINAL PROCESSING OF FIBRILLAR PROCOLLAGENS IS THE ONLY BMP-1-DEPENDENT ACTIVITY TO BE ENHANCED BY PCPE-1

    Catherine Moali;Bernard Font;Florence Ruggiero;Denise Eichenberger

  • Unhydroxylated triple helical collagen I produced in transgenic plants provides new clues on the role of hydroxyproline in collagen folding and fibril formation.

    Stéphanie Perret;Christine Merle;Simonetta Bernocco;Patricia Berland

  • Development of a reconstructed cornea from collagen-chondroitin sulfate foams and human cell cultures.

    N Engin Vrana;Nicolas Builles;Virginie Justin;Jurgen Bednarz

Frequent Co-Authors

Darwin J. Prockop
Darwin J. Prockop Texas A&M University
Karl E. Kadler
Karl E. Kadler University of Manchester
Leena Bruckner-Tuderman
Leena Bruckner-Tuderman University of Freiburg
Jerome Gross
Jerome Gross Harvard University
Åke Oldberg
Åke Oldberg Lund University
Cay M. Kielty
Cay M. Kielty Wellcome Centre for Cell-Matrix Research
Nicole M. Thielens
Nicole M. Thielens Grenoble Alpes University
Michael E. Grant
Michael E. Grant Wellcome Centre for Cell-Matrix Research
Alain Colige
Alain Colige University of Liège

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