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D-Index & Metrics

Chemistry

D-Index
65
Citations
15024
World Ranking
7666
National Ranking
2245

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors

Overview

Joshua Rokach is affiliated with the Florida Institute of Technology in the United States. Their research predominantly focuses on Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these broad fields, their work concentrates on subfields including Physiology, Biochemistry, Immunology, Microbiology, and Organic Chemistry.

The main topics in Rokach's research encompass asthma and respiratory diseases, eicosanoids and hypertension pharmacology, mast cells and histamine, antimicrobial peptides and activities, pediatric health and respiratory diseases, immune cell function and interaction, and neuropeptides and animal physiology.

Rokach has contributed to several recent scholarly papers, including:

  • "Targeting the OXE receptor as a potential novel therapy for asthma" (2020), published in Biochemical Pharmacology
  • "Targeting the OXE receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates" (2021), published in British Journal of Pharmacology
  • "Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates" (2022), published in European Journal of Pharmaceutical Sciences
  • "Leukotriene receptors (version 2020.3) in the IUPHAR/BPS Guide to Pharmacology Database" (2020), published in IUPHAR/BPS Guide to Pharmacology CITE
  • "Leukotriene receptors in GtoPdb v.2023.1" (2023), published in IUPHAR/BPS Guide to Pharmacology CITE

Frequent co-authors in Rokach's work include William S. Powell, Qiuji Ye, Shishir Chourey, Chintam Nagendra Reddy, and Magnus Bäck.

Their publications frequently appear in venues such as IUPHAR/BPS Guide to Pharmacology CITE, Biochemical Pharmacology, British Journal of Pharmacology, European Journal of Pharmaceutical Sciences, and Chemical and Pharmaceutical Bulletin.

In recognition of their contributions, Joshua Rokach was named a Fellow of the National Academy of Inventors in 2018.

Best Publications

  • Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice.

    Domenico Praticò;Rajendra K. Tangirala;Daniel J. Rader;Joshua Rokach

  • Isoprostanes: formation, analysis and use as indices of lipid peroxidation in vivo.

    John A. Lawson;Joshua Rokach;Garret A. FitzGerald

  • Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor

    Guillaume Monneret;Sylvie Gravel;Michael Diamond;Joshua Rokach

  • Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid.

    William S. Powell;Joshua Rokach

  • Effects of vitamin E on lipid peroxidation in healthy persons.

    Emma A. Meagher;Orla P. Barry;John A. Lawson;Joshua Rokach

  • Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist.

    T. R. Jones;R. Zamboni;M. Belley;E. Champion

  • ALCOHOL-INDUCED GENERATION OF LIPID PEROXIDATION PRODUCTS IN HUMANS

    Emma A. Meagher;Orla P. Barry;Anne Burke;Michael R. Lucey

  • Arachidonic acid metabolism in purified human lung mast cells.

    S P Peters;D W MacGlashan;E S Schulman;R P Schleimer

  • Regioselective synthesis of acylpyrroles

    Masatoshi Kakushima;Pierre Hamel;Richard Frenette;Joshua Rokach

  • Measuring leukotrienes of slow reacting substance of anaphylaxis: development of a specific radioimmunoassay.

    E C Hayes;D L Lombardo;Y Girard;A L Maycock

  • IPF2α-I: An index of lipid peroxidation in humans

    Domenico Praticò;Orla P. Barry;John A. Lawson;Mustafa Adiyaman

  • THE ISOPROSTANES IN BIOLOGY AND MEDICINE

    Domenico Praticò;John A. Lawson;Joshua Rokach;Garret A. FitzGerald

  • Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F2-isoprostanes in human urine

    Hongwei Li;John A. Lawson;Muredach Reilly;Mustafa Adiyaman

  • Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury

    Valeria Conte;Kunihiro Uryu;Scott Fujimoto;Scott Fujimoto;Yuemang Yao

  • NOMENCLATURE OF ISOPROSTANES : A PROPOSAL

    J Rokach;S.P Khanapure;S.-W Hwang;M Adiyaman

  • Biochemistry, biology and chemistry of the 5-lipoxygenase product 5-oxo-ETE.

    William S Powell;Joshua Rokach

  • Analysis of leukotrienes by high-pressure liquid chromatography

    W.Rodney Mathews;Joshua Rokach;Robert C. Murphy

  • 15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils.

    Guillaume Monneret;Hongping Li;Julian Vasilescu;Joshua Rokach

  • The Isoprostanes: A Perspective

    J. Rokach;S.P. Khanapure;S.-W. Hwang;M. Adiyaman

  • F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.

    Domenico Praticò;Joshua Rokach;John Lawson;Garret A. FitzGerald

  • Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials.

    Joseph Quinn;Doris Kulhanek;Jessica Nowlin;Richard Jones

Frequent Co-Authors

William S. Powell
William S. Powell McGill University Health Centre
Garret A. FitzGerald
Garret A. FitzGerald University of Pennsylvania
Domenico Praticò
Domenico Praticò Temple University
Robert N. Young
Robert N. Young Simon Fraser University
Robert Zamboni
Robert Zamboni MSD (United States)
Anthony W. Ford-Hutchinson
Anthony W. Ford-Hutchinson Independent Scientist / Consultant, US
Shozo Yamamoto
Shozo Yamamoto Kyoto Women's University
Natsuo Ueda
Natsuo Ueda Kagawa University
Alan R. Brash
Alan R. Brash Vanderbilt University
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania

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