World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
46
Citations
10409
World Ranking
15871
National Ranking
430

Research.com Recognitions

  • 1963 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert N. Young is affiliated with Simon Fraser University in Canada. Their research focuses predominantly on medicine and biochemistry, genetics, and molecular biology. The subfields covered include molecular biology, pulmonary and respiratory medicine, genetics, oncology, and computational theory and mathematics.

The scientist has contributed to multiple topical areas, notably:

  • Computational Drug Discovery Methods
  • SARS-CoV-2 and COVID-19 Research
  • Estrogen and related hormone effects
  • Bone health and treatments
  • Cystic Fibrosis Research Advances
  • Advanced biosensing and bioanalysis techniques
  • Vaccines and immunoinformatics approaches

Recent publications authored by Young span a variety of journals and topics, including the following:

  • E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis, 2021, Nature Cell Biology
  • Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator, 2021, iScience
  • Lipid nanoparticle-mediated silencing of osteogenic suppressor GNAS leads to osteogenic differentiation of mesenchymal stem cells in vivo, 2022, Molecular Therapy
  • Large-Scale Virtual Screening for the Discovery of SARS-CoV-2 Papain-like Protease (PLpro) Non-covalent Inhibitors, 2023, Journal of Chemical Information and Modeling
  • Achieving enhanced bone regeneration using monetite granules with bone anabolic drug conjugates (C3 and C6) in rat mandibular defects, 2020, Journal of Biomedical Materials Research Part B Applied Biomaterials

Young's frequent co-authors include:

  • Artem Cherkasov
  • Jason R. Smith
  • Fuqiang Ban
  • N.C.J. Strynadka
  • Srinivas Kantham

The scientist's work has been published in various venues including Nature Cell Biology, iScience, Molecular Therapy, Journal of Chemical Information and Modeling, and Emerging Microbes & Infections.

In 1963, Robert N. Young was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • Etoricoxib (MK-0663): Preclinical Profile and Comparison with Other Agents That Selectively Inhibit Cyclooxygenase-2

    D Riendeau;M D Percival;C Brideau;S Charleson

  • The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor

    P Prasit;Z Wang;C Brideau;C.-C Chan

  • The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

    Jacques Yves Gauthier;Nathalie Chauret;Wanda Cromlish;Sylvie Desmarais

  • Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.

    D Riendeau;M D Percival;S Boyce;C Brideau

  • L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

    J Gillard;A W Ford-Hutchinson;C Chan;S Charleson

  • Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist.

    T. R. Jones;R. Zamboni;M. Belley;E. Champion

  • Quinolines as potent 5-lipoxygenase inhibitors: synthesis and biological profile of L-746,530.

    Daniel Dubé;Marc Blouin;Christine Brideau;Chi-Chung Chan

  • Measuring leukotrienes of slow reacting substance of anaphylaxis: development of a specific radioimmunoassay.

    E C Hayes;D L Lombardo;Y Girard;A L Maycock

  • Prostaglandin receptor EP(4) mediates the bone anabolic effects of PGE(2).

    M. Machwate;S. Harada;C. T. Leu;G. Seedor

  • 2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors

    Richard W Friesen;Christine Brideau;Chi Chung Chan;Stella Charleson

  • Inhibitors of 5-lipoxygenase: a therapeutic potential yet to be fully realized?

    Robert N. Young

  • Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor.

    Christine Brideau;Chi-Chung Chan;S. Charleson;Deschenes Denis

  • Silicon directed ipso-substitution of polymer bound arylsilanes: Preparation of biaryls via the Suzuki cross-coupling reaction☆

    Yongxin Han;Shawn D Walker;Robert N Young

  • Trifluoroethylamines as amide isosteres in inhibitors of cathepsin K.

    W. Cameron Black;Christopher I. Bayly;Dana E. Davis;Sylvie Desmarais

  • Inhibition of Autophagosome Formation by the Benzoporphyrin Derivative Verteporfin

    Elizabeth Donohue;Andrew Tovey;A. Wayne Vogl;Steve Arns

  • Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction

    M. Labelle;M. Belley;Y. Gareau;J.Y. Gauthier

  • The synthesis of a leukotriene with SRS-like activity

    Joshua Rokach;Yves Girard;Yvan Guindon;Joseph G. Atkinson

  • Prostaglandin E2-bisphosphonate conjugates: potential agents for treatment of osteoporosis.

    L. Gil;Yongxin Han;E. E. Opas;G. A. Rodan

  • Discovery of a potent and selective agonist of the prostaglandin EP4 receptor.

    Xavier Billot;Anne Chateauneuf;Nathalie Chauret;Danielle Denis

  • Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole Derivatives

    Ravi Shashi Nayana Munuganti;Eric Leblanc;Peter Axerio-Cilies;Christophe Labriere

Frequent Co-Authors

Robert Zamboni
Robert Zamboni MSD (United States)
Joshua Rokach
Joshua Rokach Florida Institute of Technology
Anthony W. Ford-Hutchinson
Anthony W. Ford-Hutchinson Independent Scientist / Consultant, US
Denis Riendeau
Denis Riendeau MSD (United States)
Joseph A. Mancini
Joseph A. Mancini MSD (United States)
Marc D. Grynpas
Marc D. Grynpas University of Toronto
Michael Glogauer
Michael Glogauer University of Toronto
Michael J. Therien
Michael J. Therien Duke University
Neil E. Reiner
Neil E. Reiner University of British Columbia
Donald W. Nicholson
Donald W. Nicholson MSD (United States)

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Chemistry in the USA opens doors to various interdisciplinary career paths, especially in forensic and medical fields. For those interested in combining science with legal investigations, exploring online forensic science courses can provide a flexible and affordable way to acquire specialized knowledge.

Many students also consider advanced studies such as an online master's in forensic psychology, which complements a chemistry background by focusing on the psychological aspects of criminal behavior and investigation.

Those aiming for hands-on roles in medical legal investigations might find valuable guidance in learning how to become a medical examiner assistant. This career involves supporting forensic pathologists in autopsy procedures and evidence collection, making it ideal for chemistry graduates interested in applied science roles.

Finally, a broad look at forensic science careers reveals a variety of opportunities ranging from laboratory technician positions to specialized analytical roles. Understanding these options can help chemistry students align their education with career goals in the forensic and medical sectors.

Exploring these related online degrees and career pathways can enhance your skill set and increase your competitiveness in a dynamic job market.

Best Scientists Citing Robert N. Young

Trending Scientists