World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
11058
World Ranking
17060
National Ranking
7034

Overview

Le T. Duong is affiliated with MSD (United States) and has focused research efforts primarily within the field of Medicine. Their work encompasses several subfields, including Molecular Biology, Food Science, Orthopedics and Sports Medicine, Oncology, and Rheumatology.

The scholar's research topics cover a range of subjects related to bone metabolism and diseases, with specialized attention given to bone health and osteoporosis research as well as treatments for bone-related conditions. Additional research interests include osteoarthritis treatment and mechanisms, natural product bioactivities and synthesis, migraine and headache studies, and cardiovascular syncope and autonomic disorders.

Among their recent publications are:

  • Effects of Odanacatib on Bone Structure and Quality in Postmenopausal Women With Osteoporosis: 5-Year Data From the Phase 3 Long-Term Odanacatib Fracture Trial (LOFT) and its Extension, 2020, Journal of Bone and Mineral Research
  • Lead optimization of cathepsin K inhibitors for the treatment of Osteoarthritis, 2022, Bioorganic & Medicinal Chemistry Letters
  • Flavonoid content and antifungal activity of Celastrus hindsii leaf extract obtained by supercritical carbon dioxide using ethanol as co-solvent, 2023, Biocatalysis and Agricultural Biotechnology
  • The prevalence of headache disorders among medical students in Vietnam: a cross-sectional study, 2024, The Journal of Headache and Pain
  • Foam-mat drying of lucuma powder: Mathematical and artificial modeling of drying kinetics, physicochemical and microstructural properties, 2025, Journal of Agriculture and Food Research

Le T. Duong frequently publishes in the following venues:

  • The Journal of Headache and Pain
  • Journal of Agriculture and Food Research
  • SSRN Electronic Journal
  • Life Sciences
  • Journal of Bone and Mineral Research

Collaborations appear as a notable aspect of their work, with frequent coauthors including Gregg Wesolowski, Shawn J. Stachel, Hilde Giezek, Seth Clark, and Dosinda Cohn.

Best Publications

  • Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis.

    Tadashi Hayami;Maureen Pickarski;Ya Zhuo;Gregg A. Wesolowski

  • The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model.

    Tadashi Hayami;Maureen Pickarski;Gregg A. Wesolowski;Julia Mclane

  • The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

    Jacques Yves Gauthier;Nathalie Chauret;Wanda Cromlish;Sylvie Desmarais

  • Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells.

    Eijiro Jimi;Ichiro Nakamura;Le T. Duong;Tetsuro Ikebe

  • PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase.

    L T Duong;P T Lakkakorpi;I Nakamura;M Machwate

  • Integrins and signaling in osteoclast function

    Le T. Duong;Päivi Lakkakorpi;Ichiro Nakamura;Gideon A. Rodan

  • Involvement of alpha(v)beta3 integrins in osteoclast function

    Ichiro Nakamura;Le T. Duong;Sevgi B. Rodan;Gideon A. Rodan

  • Role of alpha(v)beta(3) integrin in osteoclast migration and formation of the sealing zone

    I. Nakamura;M.F. Pilkington;P.T. Lakkakorpi;L. Lipfert

  • The osteoclast, bone remodelling and treatment of metabolic bone disease.

    Brendan F. Boyce;Elizabeth Rosenberg;Anne E. de Papp;Le T. Duong

  • Isolation, characterization, and cDNA cloning of a vampire bat salivary plasminogen activator.

    S J Gardell;L T Duong;R E Diehl;J D York

  • Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey.

    Tara Cusick;Charles M Chen;Brenda L Pennypacker;Maureen Pickarski

  • Effect of the cathepsin K inhibitor odanacatib on bone resorption biomarkers in healthy postmenopausal women: two double-blind, randomized, placebo-controlled phase I studies.

    SA Stoch;S Zajic;J Stone;DL Miller

  • Expression of the cartilage derived anti-angiogenic factor chondromodulin-i decreases in the early stage of experimental osteoarthritis

    Tadashi Hayami;Haruko Funaki;Kiyoshi Yaoeda;Kaori Mitui

  • Inhibition of cathepsin K reduces cartilage degeneration in the anterior cruciate ligament transection rabbit and murine models of osteoarthritis

    Tadashi Hayami;Ya Zhuo;Gregg A. Wesolowski;Maureen Pickarski

  • The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14-34 region.

    Michael P. Caulfield;Roberta L. McKEE;Mark E. Goldman;Le T. Duong

  • Cathepsin K inhibitors prevent bone loss in estrogen‐deficient rabbits

    Brenda L Pennypacker;Le T Duong;Tara E Cusick;Patricia J Masarachia

  • Nonpeptide alphavbeta3 antagonists. 8. In vitro and in vivo evaluation of a potent alphavbeta3 antagonist for the prevention and treatment of osteoporosis.

    John H Hutchinson;Wasyl Halczenko;Karen M Brashear;Michael J Breslin

  • Tyrosine Phosphorylation of p130Cas Is Involved in Actin Organization in Osteoclasts

    Ichiro Nakamura;Eijiro Jimi;Le T. Duong;Takahisa Sasaki

  • STABLE ASSOCIATION OF PYK2 AND P130CAS IN OSTEOCLASTS AND THEIR CO-LOCALIZATION IN THE SEALING ZONE

    Päivi T. Lakkakorpi;Päivi T. Lakkakorpi;Ichiro Nakamura;Rose M. Nagy;J. Thomas Parsons

  • Convergence of αvβ3Integrin–And Macrophage Colony Stimulating Factor–Mediated Signals on Phospholipase Cγ in Prefusion Osteoclasts

    Ichiro Nakamura;Lorraine Lipfert;Gideon A. Rodan;Le T. Duong

Frequent Co-Authors

Gideon A. Rodan
Gideon A. Rodan MSD (United States)
George D. Hartman
George D. Hartman Janssen (Belgium)
Michael Rosenblatt
Michael Rosenblatt MSD (United States)
Mark M. Banaszak Holl
Mark M. Banaszak Holl Monash University
Richard Hargreaves
Richard Hargreaves Harvard Medical School
Denis Riendeau
Denis Riendeau MSD (United States)
Punam K. Saha
Punam K. Saha University of Iowa
Michael Chorev
Michael Chorev Harvard University
Klaus Klaushofer
Klaus Klaushofer University of Vienna
Natalie A. Sims
Natalie A. Sims St Vincents Institute of Medical Research

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a future in Biology and Biochemistry opens the door to a variety of healthcare and science careers. Many students consider medical assistant programs to gain quick entry into the workforce, often with the added benefit of financial aid support.

For those who wish to advance their qualifications, pathway options such as an ma to lpn bridge program allow medical assistants to build upon their skills and become Licensed Practical Nurses. This can provide more responsibility, higher earning potential, and new growth opportunities.

If you prefer to accelerate your academic journey, an accelerated biology degree makes it possible to earn credentials faster and jumpstart your scientific or healthcare career.

Finally, aspiring nurses may be interested in online nursing programs that offer flexible study options and a direct path into nursing. Whichever route you choose, online degrees can provide the flexibility needed to balance studies with other commitments.

Best Scientists Citing Le T. Duong

Trending Scientists