D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 81 Citations 29,861 148 World Ranking 8974 National Ranking 4869

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Gideon A. Rodan mainly investigates Osteoclast, Internal medicine, Endocrinology, Bone resorption and Bone remodeling. His Osteoclast study combines topics from a wide range of disciplines, such as Cancer research, Bisphosphonate, Geranylgeranylation, Cell biology and Resorption. The various areas that Gideon A. Rodan examines in his Internal medicine study include Bioinformatics and Osteoblast.

The Endocrinology study combines topics in areas such as Angiogenesis and Cycloheximide. He combines subjects such as Epiphyseal plate, Integrin, Mevalonate pathway and Membrane ruffling with his study of Bone resorption. His studies deal with areas such as Osteoarthritis, Osteoporosis, Pathology, Anterior cruciate ligament and Cartilage as well as Bone remodeling.

His most cited work include:

  • Principles of bone biology (1609 citations)
  • Therapeutic approaches to bone diseases. (1433 citations)
  • Control of osteoblast function and regulation of bone mass (1138 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Internal medicine, Endocrinology, Osteoclast, Bone resorption and Cell biology. His Internal medicine study frequently links to other fields, such as Osteoblast. The concepts of his Endocrinology study are interwoven with issues in Parathyroid hormone, In vivo and Cancellous bone.

His studies in Osteoclast integrate themes in fields like Multinucleate, Cancer research, Immunology, Cytoskeleton and Extracellular matrix. His research in Bone resorption focuses on subjects like Bisphosphonate, which are connected to Farnesyl diphosphate synthase and Pharmacology. His work deals with themes such as Integrin and Podosome, which intersect with Cell biology.

He most often published in these fields:

  • Internal medicine (39.51%)
  • Endocrinology (37.65%)
  • Osteoclast (24.69%)

What were the highlights of his more recent work (between 2003-2012)?

  • In vivo (12.35%)
  • Endocrinology (37.65%)
  • Internal medicine (39.51%)

In recent papers he was focusing on the following fields of study:

Gideon A. Rodan mostly deals with In vivo, Endocrinology, Internal medicine, Biochemistry and Pharmacokinetics. In his research, Stereochemistry is intimately related to In vitro, which falls under the overarching field of In vivo. His research in Endocrinology is mostly concerned with Thermoregulation.

When carried out as part of a general Biochemistry research project, his work on Cathepsin K, Apoptosis, Prostaglandin E and Forskolin is frequently linked to work in Sphingosine kinase, therefore connecting diverse disciplines of study. His Bone resorption research is multidisciplinary, incorporating perspectives in Ovariectomized rat, Bone disease and Biomedical engineering. Gideon A. Rodan interconnects Osteoarthritis, Bisphosphonate, Anterior cruciate ligament, Cartilage and Bone remodeling in the investigation of issues within Osteoclast.

Between 2003 and 2012, his most popular works were:

  • The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. (457 citations)
  • Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis. (450 citations)
  • The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. (344 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Bone remodeling, Bone resorption, Anatomy, Osteoclast and Bisphosphonate. Gideon A. Rodan works mostly in the field of Bone remodeling, limiting it down to topics relating to Pathology and, in certain cases, Chondrocyte. His study in Bone mineral extends to Bone resorption with its themes.

Gideon A. Rodan has included themes like Geranyltranstransferase, Mechanism of action, Prenylation, Protein prenylation and Pharmacology in his Osteoclast study. His research integrates issues of Bone disease, Drug discovery and Farnesyl diphosphate synthase in his study of Bisphosphonate. His Augment investigation overlaps with Cortical bone, Internal medicine and Endocrinology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Therapeutic approaches to bone diseases.

Gideon A. Rodan;T. John Martin.
Science (2000)

2305 Citations

Control of osteoblast function and regulation of bone mass

Shun-ichi Harada;Gideon A. Rodan.
Nature (2003)

1865 Citations

Principles of bone biology

John P. Bilezikian;Lawrence G. Raisz;Gideon A. Rodan.
(1996)

1609 Citations

Bisphosphonates: mechanisms of action.

Gideon A. Rodan;Herbert A. Fleisch.
Journal of Clinical Investigation (1996)

1247 Citations

Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.

Masahiko Sato;William Grasser;Naoto Endo;Robert Akins.
Journal of Clinical Investigation (1991)

1227 Citations

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

J. E. Fisher;M. J. Rogers;J. M. Halasy;S. P. Luckman.
Proceedings of the National Academy of Sciences of the United States of America (1999)

963 Citations

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.

Valeria Poli;Raffaella Balena;Elena Fattori;Angelo Markatos.
The EMBO Journal (1994)

851 Citations

Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties.

Sevgi B. Rodan;Yasuo Imai;Mark A. Thiede;Gregg Wesolowski.
Cancer Research (1987)

779 Citations

The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model.

Tadashi Hayami;Maureen Pickarski;Gregg A. Wesolowski;Julia Mclane.
Arthritis & Rheumatism (2004)

702 Citations

Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis.

Tadashi Hayami;Maureen Pickarski;Ya Zhuo;Gregg A. Wesolowski.
Bone (2006)

661 Citations

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