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Biology and Biochemistry

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119
Citations
51546
World Ranking
673
National Ranking
427

Medicine

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119
Citations
51650
World Ranking
3903
National Ranking
2135

Overview

Roland Baron is a researcher affiliated with Harvard University in the United States. Their scholarly work spans multiple areas within biochemistry, genetics, and molecular biology, as well as medicine. The subfields of study that Baron has contributed to include molecular biology, genetics, oncology, physiology, and rheumatology.

The scientist's main research topics focus on bone metabolism and diseases, bone health and treatments, Wnt/β-catenin signaling in development and cancer, adipose tissue and metabolism, cancer-related gene regulation, mesenchymal stem cell research, and connective tissue disorders research.

Baron's recent publications demonstrate ongoing contributions to the understanding of bone biology and related physiological processes. Selected papers include:

  • Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo, 2020, published in eLife
  • RANKL regulates male reproductive function, 2021, published in Nature Communications
  • Periosteal stem cells control growth plate stem cells during postnatal skeletal growth, 2022, published in Nature Communications
  • Effects of abaloparatide and teriparatide on bone resorption and bone formation in female mice, 2020, published in Bone Reports
  • Perivascular osteoprogenitors are associated with transcortical channels of long bones, 2020, published in Stem Cells

Frequent coauthors indicate active collaboration with several researchers in the field. These include Francesca Gori, Clifford J. Rosen, Dorothy Hu, Phuong Le, and Mary Bouxsein.

The venues where Roland Baron commonly publishes reflect a focus on bone and molecular biology research. These venues are:

  • Bone
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Journal of Bone and Mineral Research
  • JCI Insight

Best Publications

  • LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

    Y. Q. Gong;R. B. Slee;N. Fukai;G. Rawadi

  • WNT signaling in bone homeostasis and disease: from human mutations to treatments

    Roland Baron;Michaela Kneissel

  • Cell-mediated Extracellular Acidification and Bone-resorption - Evidence for a Low Ph in Resorbing Lacunae and Localization of a 100-kd Lysosomal Membrane-protein At the Osteoclast Ruffled Border

    R. Baron;L. Neff;D. Louvard;Pierre J. Courtoy

  • TARGETED ABLATION OF THE VITAMIN D RECEPTOR : AN ANIMAL MODEL OF VITAMIN D-DEPENDENT RICKETS TYPE II WITH ALOPECIA

    Yan Chun Li;Alison E. Pirro;Michael Amling;Gunter Delling

  • BMP-2 Controls Alkaline Phosphatase Expression and Osteoblast Mineralization by a Wnt Autocrine Loop

    Georges Rawadi;Béatrice Vayssière;Fred Dunn;Roland Baron

  • Denosumab and bisphosphonates: different mechanisms of action and effects.

    Roland Baron;Serge Livio Ferrari;R. Graham G. Russell;R. Graham G. Russell

  • Targeting the Wnt/β-Catenin Pathway to Regulate Bone Formation in the Adult Skeleton

    Roland Baron;Georges Rawadi

  • Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass.

    Frederic Morvan;Kim Boulukos;Philippe Clément-Lacroix;Sergio Roman Roman

  • Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice.

    Yan Chun Li;Michael Amling;Michael Amling;Alison E. Pirro;Matthias Priemel

  • Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice.

    Philippe Clément-Lacroix;Minrong Ai;Frederic Morvan;Sergio Roman-Roman

  • Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation.

    Eleanor C. Weir;William M. Philbrick;Michael Amling;Lynn A. Neff

  • Spred is a Sprouty-related suppressor of Ras signalling

    Toru Wakioka;Atsuo Sasaki;Reiko Kato;Reiko Kato;Takanori Shouda

  • Rescue of the Skeletal Phenotype of Vitamin D Receptor-Ablated Mice in the Setting of Normal Mineral Ion Homeostasis: Formal Histomorphometric and Biomechanical Analyses

    Michael Amling;Matthias Priemel;Timothy Holzmann;Kelli Chapin

  • Hepatocellular carcinoma: evaluation with biphasic, contrast-enhanced, helical CT.

    R L Baron;J H Oliver rd;G D Dodd rd;M Nalesnik

  • Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

    Hyeonwoo Kim;Christiane D. Wrann;Mark Jedrychowski;Sara Vidoni

  • Cbl Associates with Pyk2 and Src to Regulate Src Kinase Activity, αvβ3 Integrin-Mediated Signaling, Cell Adhesion, and Osteoclast Motility

    Archana Sanjay;Adam Houghton;Lynn Neff;Emilia DiDomenico

  • A Functional Link between Dynamin and the Actin Cytoskeleton at Podosomes

    Gian-Carlo Ochoa;Vladimir I. Slepnev;Lynn Neff;Niels Ringstad

  • The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

    Matthew B. Greenblatt;Jae-Hyuck Shim;Weiguo Zou;Despina Sitara

  • Hepatic artery stenosis and thrombosis in transplant recipients: Doppler diagnosis with resistive index and systolic acceleration time.

    G D Dodd;D S Memel;A B Zajko;R L Baron

  • Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl ring finger and UbcH7

    Masahiro Yokouchi;Takeshi Kondo;Adam Houghton;Marcjanna Bartkiewicz

Frequent Co-Authors

William C. Horne
William C. Horne Harvard University
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center
Clifford J. Rosen
Clifford J. Rosen Maine Medical Center
Beate Lanske
Beate Lanske Harvard University
Natalie A. Sims
Natalie A. Sims St Vincents Institute of Medical Research
Michael P. Federle
Michael P. Federle Stanford University
Henry M. Kronenberg
Henry M. Kronenberg Harvard University
Sakae Tanaka
Sakae Tanaka University of Tokyo
Kazuhiro Aoki
Kazuhiro Aoki National Institutes of Natural Sciences
Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University

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