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Karl L. Insogna

Karl L. Insogna

D-Index & Metrics

Medicine

D-Index
90
Citations
25858
World Ranking
12339
National Ranking
6320

Research.com Recognitions

  • 1997 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Karl L. Insogna is affiliated with Yale University in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily focuses on nephrology, oncology, molecular biology, genetics, and pulmonary and respiratory medicine.

The scientist has contributed to diverse topics within biomedical research. Major themes in their work include parathyroid disorders and treatments, bone health and treatments, bone health and osteoporosis research, medical imaging and pathology studies, bone metabolism and diseases, heterotopic ossification and related conditions, and connective tissue disorders research.

Frequent publication venues for Insogna include the Journal of the Endocrine Society, Journal of Bone and Mineral Research, Zenodo (CERN European Organization for Nuclear Research), The Journal of Clinical Endocrinology & Metabolism, and Calcified Tissue International.

Among recent papers authored in collaboration with other researchers are:

  • The clinician's guide to prevention and treatment of osteoporosis, 2022, Osteoporosis International
  • Update on Osteoporosis Screening and Management, 2021, Medical Clinics of North America
  • Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism, 2020, Journal of Bone and Mineral Research
  • Burosumab for the Treatment of Tumor-Induced Osteomalacia, 2020, Journal of Bone and Mineral Research
  • Burosumab treatment in adults with X-linked hypophosphataemia: 96-week patient-reported outcomes and ambulatory function from a randomised phase 3 trial and open-label extension, 2021, RMD Open

Insogna has collaborated frequently with several researchers, including Thomas O. Carpenter, Meiling Zhu, Thomas J. Weber, Suzanne M. Jan de Beur, and Christine Simpson. Collaboration counts with these co-authors range from 7 to 15 joint publications.

In their career, Insogna has authored numerous papers-74 in medicine and 22 in biochemistry, genetics, and molecular biology-reflecting the breadth of their scientific inquiry. Their work spans clinical and molecular investigations primarily concerned with bone and parathyroid related diseases.

Insogna was recognized in 1997 as a Fellow of the American Association for the Advancement of Science (AAAS), indicating engagement with the broader scientific community and contributions consistent with the standards of this professional organization.

Best Publications

  • High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5

    Lynn M. Boyden;Junhao Mao;Joseph Belsky;Lyle Mitzner

  • Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

    Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron

  • Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

    Vijay K. Yadav;Je Hwang Ryu;Nina Suda;Kenji F. Tanaka

  • A clinician's guide to X-linked hypophosphatemia.

    Thomas O Carpenter;Erik A Imel;Ingrid A Holm;Suzanne M Jan de Beur

  • Humoral hypercalcemia of cancer. Identification of a novel parathyroid hormone-like peptide.

    Arthur E. Broadus;Marguerite Mangin;Kyoji Ikeda;Karl L. Insogna

  • Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy.

    W J Burtis;T Wu;C Bunch;J J Wysolmerski

  • The impact of dietary protein on calcium absorption and kinetic measures of bone turnover in women.

    Jane E. Kerstetter;Kimberly O. O’Brien;Donna M. Caseria;Diane E. Wall

  • Cross-cultural association between dietary animal protein and hip fracture: A hypothesis

    Benjamin J. Abelow;Theodore R. Holford;Karl L. Insogna

  • Low Protein Intake: The Impact on Calcium and Bone Homeostasis in Humans

    Jane E Kerstetter;Kimberly O O'Brien;Karl L Insogna

  • Dietary protein, calcium metabolism, and skeletal homeostasis revisited

    Jane E Kerstetter;Kimberly O O’Brien;Karl L Insogna

  • Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia

    Thomas O. Carpenter;Erik A. Imel;Mary D. Ruppe;Thomas J. Weber

  • Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells.

    S B Rodan;K L Insogna;A M Vignery;A F Stewart

  • Multisystem study of 20 older adults with Williams syndrome.

    Elizabeth M. Cherniske;Thomas O. Carpenter;Cheryl Klaiman;Eytan Young

  • A parathyroid hormone-like protein from cultured human keratinocytes.

    JJ Merendino;KL Insogna;KL Insogna;LM Milstone;LM Milstone;AE Broadus

  • A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti-FGF23 Antibody, in Adults With X-Linked Hypophosphatemia: Week 24 Primary Analysis.

    Karl L Insogna;Karine Briot;Erik A Imel;Peter Kamenický

  • Increasing dietary protein requirements in elderly people for optimal muscle and bone health.

    Erin Gaffney-Stomberg;Karl L. Insogna;Nancy R. Rodriguez;Jane E. Kerstetter

  • Dietary protein affects intestinal calcium absorption.

    J E Kerstetter;K O O'Brien;K L Insogna

  • Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone

    Bart O Williams;Karl L Insogna

  • Identification of adenylate cyclase-stimulating activity and cytochemical glucose-6-phosphate dehydrogenase-stimulating activity in extracts of tumors from patients with humoral hypercalcemia of malignancy

    Andrew F. Stewart;Karl L. Insogna;David Goltzman;Arthur E. Broadus

  • Dietary protein and bone health: a systematic review and meta-analysis from the National Osteoporosis Foundation

    Marissa M Shams-White;Mei Chung;Mengxi Du;Zhuxuan Fu

Frequent Co-Authors

Munro Peacock
Munro Peacock Indiana University
Francis H. Glorieux
Francis H. Glorieux McGill University
Carlos M. Isales
Carlos M. Isales Augusta University
Taisheng Li
Taisheng Li Peking Union Medical College Hospital
Michael Centrella
Michael Centrella Yale University
Roland Baron
Roland Baron Harvard University
Sophie Leboulleux
Sophie Leboulleux University of Geneva
Rajiv Kumar
Rajiv Kumar Mayo Clinic
Kitt Falk Petersen
Kitt Falk Petersen Yale University
Stuart H. Ralston
Stuart H. Ralston University of Edinburgh

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