World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
70
Citations
22899
World Ranking
2248
National Ranking
34

Overview

Wim Van Hul is affiliated with the University of Antwerp in Belgium. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Genetics and Molecular Biology as key subfields. Additional areas of study include Oncology, Cell Biology, and Rheumatology.

The main topics of Van Hul's work include:

  • Bone health and treatments
  • Connective tissue disorders research
  • Bone Metabolism and Diseases
  • Dermatological and Skeletal Disorders
  • Wnt/β-catenin signaling in development and cancer
  • Genomics and Rare Diseases
  • Epigenetics and DNA Methylation

Van Hul has published extensively in several scientific venues. The most frequent publication forums are:

  • Frontiers in Endocrinology
  • Bone Reports
  • Calcified Tissue International
  • Bone
  • Genes

Among recent papers, notable titles include:

  • WNT Signaling and Bone: Lessons From Skeletal Dysplasias and Disorders, 2020, Frontiers in Endocrinology
  • Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome, 2020, The American Journal of Human Genetics
  • Insights into the multifactorial causation of obesity by integrated genetic and epigenetic analysis, 2020, Obesity Reviews
  • A Roadmap to Gene Discoveries and Novel Therapies in Monogenic Low and High Bone Mass Disorders, 2021, Frontiers in Endocrinology
  • Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques, 2021, Frontiers in Endocrinology

Van Hul collaborates frequently with a group of coauthors including:

  • Geert Mortier
  • Eveline Boudin
  • Yentl Huybrechts
  • Gretl Hendrickx
  • Ellen Steenackers

The researcher's work covers a range of genetic and molecular mechanisms underlying bone and connective tissue disorders, with an integrative approach that blends genetic discoveries with epigenetic and cellular analysis. This multidisciplinary expertise supports advances in understanding skeletal diseases and exploring potential therapeutic approaches.

Best Publications

  • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

    Karol Estrada;Unnur Styrkarsdottir;Evangelos Evangelou;Yi-Hsiang Hsu

  • Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β–amyloid precursor protein gene

    Lydia Hendriks;Cornelia M. van Duijn;Patrick Cras;Marc Cruts

  • TGF-Β1-induced migration of bone mesenchymal stem cells couples bone resorption with formation

    Yi Tang;Xiangwei Wu;Xiangwei Wu;Xiangwei Wu;Weiqi Lei;Lijuan Pang;Lijuan Pang

  • Transforming Growth Factor-β1 to the Bone

    Katrien Janssens;Peter ten Dijke;Sophie Janssens;Wim Van Hul

  • Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators.

    Wendy Balemans;Wim Van Hul

  • Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

    Atsuhiko Ichimura;Akira Hirasawa;Odile Poulain-Godefroy;Odile Poulain-Godefroy;Amélie Bonnefond;Amélie Bonnefond

  • Six Novel Missense Mutations in the LDL Receptor-Related Protein 5 (LRP5) Gene in Different Conditions with an Increased Bone Density

    Liesbeth Van Wesenbeeck;Erna Cleiren;Jeppe Gram;Rodney K. Beals

  • Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

    Jan Hellemans;Olena Preobrazhenska;Andy Willaert;Philippe Debeer

  • Albers-Schönberg disease (autosomal dominant osteopetrosis, type II) results from mutations in the ClCN7 chloride channel gene

    Erna Cleiren;Olivier Bénichou;Els Van Hul;Jeppe Gram

  • Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease

    Lynne J. Hocking;Gavin J.A. Lucas;Anna Daroszewska;Jon Mangion

  • Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia.

    J R Hurvitz;W M Suwairi;W Van Hul;H El-Shanti

  • PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis

    Sven Francque;An Verrijken;Sandrine Caron;Janne Prawitt

  • Large-Scale Analysis of Association Between LRP5 and LRP6 Variants and Osteoporosis

    Joyce B J. van Meurs;Thomas A. Trikalinos;Thomas A. Trikalinos;Stuart H. Ralston;Susana Balcells

  • Bone Overgrowth-associated Mutations in the LRP4 Gene Impair Sclerostin Facilitator Function

    Olivier Leupin;Elke Piters;Christine Halleux;Shouih Hu

  • Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling.

    Minrong Ai;Sheri L. Holmen;Wim Van Hul;Bart O. Williams

  • A look behind the scenes: the risk and pathogenesis of primary osteoporosis

    Gretl Hendrickx;Eveline Boudin;Wim Van Hul

  • Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes.

    Wim Wuyts;Wim Van Hul

  • LRP5 and Wnt signaling: a union made for bone.

    Mark L Johnson;Kimberley Harnish;Roel Nusse;Wim Van Hul

  • EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.

    Judith V.M.G. Bovée;Anne-Marie Cleton-Jansen;Wim Wuyts;Goedele Caethoven

  • Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans

    Liesbeth Van Wesenbeeck;Paul R. Odgren;Fraser Coxon;Annalisa Frattini

Frequent Co-Authors

Luc Van Gaal
Luc Van Gaal University of Antwerp
Geert Mortier
Geert Mortier University of Antwerp
Wim Wuyts
Wim Wuyts University of Antwerp
Stuart H. Ralston
Stuart H. Ralston University of Edinburgh
Kim Brixen
Kim Brixen University of Southern Denmark
Jean-Pierre Devogelaer
Jean-Pierre Devogelaer Université Catholique de Louvain
Jens Bollerslev
Jens Bollerslev Oslo University Hospital
Erik Fransen
Erik Fransen University of Antwerp
Philippe Froguel
Philippe Froguel Imperial College London

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Genetics in the USA opens doors to a range of healthcare careers that increasingly value flexibility and advanced skills. Many students look for rn to bsn programs with no clinicals, which allow working nurses to advance their education online while balancing work and family commitments. Such programs can provide strong foundational knowledge for transitioning into genetics-based nursing roles.

If you’re interested in taking your education further, pursuing the fastest bsn to dnp program can equip you with leadership and research skills critical in genetics and genomics. For those looking for a quicker entry into healthcare, options like an accelerated ma program can fast-track your pathway to becoming a medical assistant with a focus on genetic testing or laboratory work.

Many students also seek out the easiest online dnp programs to balance advanced study with work and life responsibilities. All of these online degree options support evolving career pathways in genetics, allowing you to customize your education and professional journey.

Best Scientists Citing Wim Van Hul

Trending Scientists