D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 73 Citations 16,516 316 World Ranking 15953 National Ranking 8134

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Leonard J. Deftos focuses on Internal medicine, Endocrinology, Calcitonin, Parathyroid hormone and Parathyroid hormone-related protein. The Internal medicine study combines topics in areas such as Molecular biology and Gene expression. His studies in Endocrinology integrate themes in fields like Cell culture, Calcium and Chromogranin A.

His Calcitonin research incorporates elements of Immunoassay, Hormone, Basal and Thyroid carcinoma. His Parathyroid hormone study combines topics from a wide range of disciplines, such as Amino acid, Secretion, Peptide sequence and Radioimmunoassay. His Parathyroid hormone-related protein study incorporates themes from Immunocytochemistry, Messenger RNA, Lung and Prostate.

His most cited work include:

  • 1,25-dihydroxyvitamin D3 receptors in human leukocytes (881 citations)
  • Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups. (622 citations)
  • New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease. (592 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Internal medicine, Endocrinology, Calcitonin, Parathyroid hormone-related protein and Parathyroid hormone. His study in Calcium, Radioimmunoassay, Chromogranin A, Cancer and Receptor falls under the purview of Internal medicine. His research integrates issues of Molecular biology and Endocrine system in his study of Chromogranin A.

His research in Endocrinology intersects with topics in Calcium metabolism and Cell culture. In general Calcitonin, his work in Calcitonin secretion is often linked to Pentagastrin linking many areas of study. His work in Parathyroid hormone-related protein tackles topics such as Cancer research which are related to areas like Prostate cancer and Tumor progression.

He most often published in these fields:

  • Internal medicine (89.95%)
  • Endocrinology (86.14%)
  • Calcitonin (44.57%)

What were the highlights of his more recent work (between 2004-2014)?

  • Internal medicine (89.95%)
  • Endocrinology (86.14%)
  • Parathyroid hormone-related protein (27.72%)

In recent papers he was focusing on the following fields of study:

Internal medicine, Endocrinology, Parathyroid hormone-related protein, Cancer research and Pathology are his primary areas of study. His work deals with themes such as Peptide and Cell biology, which intersect with Internal medicine. Leonard J. Deftos has included themes like Calcium metabolism and Calcium in his Endocrinology study.

His Parathyroid hormone-related protein research includes elements of Cancer, Peptide sequence, Carcinoma, Lung cancer and Gene isoform. The study incorporates disciplines such as Collagen receptor, Integrin, Cell adhesion, Metastasis and Tumor progression in addition to Cancer research. His Pathology research integrates issues from Urine and Early detection.

Between 2004 and 2014, his most popular works were:

  • Knockdown of the β1 integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis (67 citations)
  • Knockdown of the β1 integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis (67 citations)
  • Direct evidence that PTHrP expression promotes prostate cancer progression in bone. (52 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

Leonard J. Deftos mostly deals with Endocrinology, Internal medicine, Tumor progression, Metastasis and Prostate cancer. He interconnects Calcium metabolism, Calcium and Matrix metalloproteinase in the investigation of issues within Endocrinology. His biological study spans a wide range of topics, including Extracellular and Chondrocyte, Cartilage.

Leonard J. Deftos studied Tumor progression and Pathology that intersect with Skeleton and Osteoclast. His research on Metastasis also deals with topics like

  • Cancer research which intersects with area such as Parathyroid hormone-related protein,
  • Pancreatic cancer which is related to area like Collagen receptor, Integrin, beta 6, Fibronectin, Cell adhesion molecule and Integrin alpha3beta1,
  • Integrin, which have a strong connection to Cancer. His study in Prostate cancer is interdisciplinary in nature, drawing from both Cell culture, Transfection, Osteoprotegerin, Cell growth and Downregulation and upregulation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

1,25-dihydroxyvitamin D3 receptors in human leukocytes

DM Provvedini;CD Tsoukas;LJ Deftos;SC Manolagas.
Science (1983)

1303 Citations

New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease.

P A Price;J G Parthemore;L J Deftos.
Journal of Clinical Investigation (1980)

918 Citations

Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups.

Andrew F. Stewart;Ronald Horst;Leonard J. Deftos;Edwin C. Cadman.
The New England Journal of Medicine (1980)

789 Citations

Secretion of chromogranin A by peptide-producing endocrine neoplasms.

Daniel T. O'Connor;Leonard J. Deftos.
The New England Journal of Medicine (1986)

573 Citations

The rate of bone mineral loss in normal men and the effects of calcium and cholecalciferol supplementation.

Eric S. Orwoll;Shelia K. Oviatt;Michael R. McClung;Leonard J. Deftos.
Annals of Internal Medicine (1990)

330 Citations

Synthesis of a biologically active N-terminal tetratriacontapeptide of parathyroid hormone.

J. T. Potts;G. W. Tregear;H. T. Keutmann;H. D. Niall.
Proceedings of the National Academy of Sciences of the United States of America (1971)

305 Citations

Expression of messenger ribonucleic acids encoding a parathyroid hormone-like peptide in normal human and animal tissues with abnormal expression in human parathyroid adenomas.

Kyoji Ikeda;Eleanor C. Weir;Marguerite Mangin;Priscilla S. Dannies.
Molecular Endocrinology (1988)

302 Citations

1,25-Dihydroxyvitamin D3 stimulates the alkaline phosphatase activity of osteoblast-like cells.

S C Manolagas;D W Burton;L J Deftos.
Journal of Biological Chemistry (1981)

277 Citations

Chromogranin A: Immunohistology reveals its universal occurrence in normal polypeptide hormone producing endocrine glands

Daniel T. O'Connor;Daniel T. O'Connor;Douglas Burton;Douglas Burton;Leonard J. Deftos;Leonard J. Deftos.
Life Sciences (1983)

271 Citations

Influence of Age and Sex on Plasma Calcitonin in Human Beings

L. J. Deftos;M. H. Weisman;G. W. Williams;D. B. Karpf.
The New England Journal of Medicine (1980)

269 Citations

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