Jeremy D. Pearson

Overview

Best Publications

• Neutrophils in development of multiple organ failure in sepsis

  KA Brown;SD Brain;JD Pearson;JD Edgeworth

  801
  Citations

• Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.

  Xu Shi-Wen;Yunliang Chen;Christopher P. Denton;Mark Eastwood

  500
  Citations

• Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1.

  Xu Shi-wen;Christopher P Denton;Michael R Dashwood;Alan M Holmes

  330
  Citations

• IgG Antiendothelial Cell Autoantibodies from Scleroderma Patients Induce Leukocyte Adhesion to Human Vascular Endothelial Cells In Vitro Induction of Adhesion Molecule Expression and Involvement of Endothelium-derived Cytokines

  Dulce Carvalho;Caroline O. S. Savage;Carol M. Black;Jeremy D. Pearson

  313
  Citations

• L-arginine transport is increased in macrophages generating nitric oxide.

  R G Bogle;A R Baydoun;J D Pearson;S Moncada

  300
  Citations

• Endothelial cell function and thrombosis.

  Jeremy D. Pearson

  291
  Citations

• Exogenous ATP raises cytoplasmic free calcium in fura-2 loaded piglet aortic endothelial cells.

  Trevor J. Hallam;Jeremy D. Pearson

  262
  Citations

• Measurement and characterisation of circulating anti-endothelial cell IgG in connective tissue diseases

  J Rosenbaum;B E Pottinger;P Woo;C M Black

  233
  Citations

• Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.

  Xu Shi-wen;Sarah L. Howat;Elisabetta A. Renzoni;Alan Holmes

  232
  Citations

• Stimulation of prostaglandin production through purinoceptors on cultured porcine endothelial cells.

  J D Pearson;L L Slakey;J L Gordon

  231
  Citations

• Nucleotide metabolism by endothelium.

  Jeremy D. Pearson;John L. Gordon

  230
  Citations

• CCN2 (Connective Tissue Growth Factor) Promotes Fibroblast Adhesion to Fibronectin

  Yunliang Chen;David J. Abraham;Xu Shi-wen;Jeremy D. Pearson

  227
  Citations

• Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell l-arginine transporter

  Richard G. Bogle;Salvador Moncada;Jeremy D. Pearson;Giovanni E. Mann

  225
  Citations

• Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cells.

  R.G. Bogle;S.B. Coade;S. Moncada;J.D. Pearson

  223
  Citations

• P2 purinoceptors on vascular endothelial cells: physiological significance and transduction mechanisms.

  Jean-Marie Boeynaems;Jeremy D. Pearson

  211
  Citations

• Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors.

  Xu Shi-Wen;Fernando Rodríguez-Pascual;Santiago Lamas;Alan Holmes

  211
  Citations

• CCN2 Is Necessary for Adhesive Responses to Transforming Growth Factor-β1 in Embryonic Fibroblasts

  Xu Shi-wen;Lee Anne Stanton;Laura Kennedy;Daphne Pala

  204
  Citations

• Circulating Humoral Factors and Endothelial Progenitor Cells in Patients With Differing Coronary Collateral Support

  Pier D. Lambiase;Richard J. Edwards;Prodromos Anthopoulos;Salman Rahman

  204
  Citations

• Characteristics of the P2 purinoceptor that mediates prostacyclin production by pig aortic endothelial cells.

  Lindsey Needham;Noel J. Cusack;Jeremy D. Pearson;John L. Gordon

  194
  Citations

• Regulation of P2y-purinoceptor-mediated prostacyclin release from human endothelial cells by cytoplasmic calcium concentration.

  Thomas D. Carter;Trevor J. Hallam;Noel J. Cusack;Jeremy D. Pearson

  193
  Citations