World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
80
Citations
23016
World Ranking
1629
National Ranking
63

Medicine

D-Index
80
Citations
22955
World Ranking
17131
National Ranking
565

Overview

Pierre Youinou is affiliated with the University of Western Brittany in France. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology. The work addresses several subfields including molecular biology, ophthalmology, nephrology, rheumatology, and immunology.

The researcher has contributed to the study of inflammasome and immune disorders, with a particular focus on ocular diseases and Behçet's syndrome. Their work also covers topics related to gout, hyperuricemia, and uric acid, as well as systemic lupus erythematosus research. Additionally, they have explored pathways involving IL-33, ST2, and innate lymphoid cells (ILC), along with diabetes and associated disorders.

Their recent publications include the following papers:

  • Uric acid increases IL-1β secretion and Caspase-1 activation in PBMCs of Behçet's disease patients: The in vitro immunomodulatory effect of xanthine oxidase inhibitor Allopurinol, 2020, International Immunopharmacology
  • Geographic Location Determines Differentially Methylated Gene Expressions in Autoimmune Diseases, 2021, Immuno

Frequent co-authors in their work include Arezki Chekaoui, Houda Belguendouz, Karima Lahmar, Fettoum Mazari, and Malika Terahi.

Their research has been published chiefly in the following venues:

  • International Immunopharmacology
  • Immuno

Overall, their academic contributions intersect key themes in immune system regulation and autoimmune disease mechanisms, with a notable emphasis on inflammation and genetic expression in relation to environmental factors.

Best Publications

  • Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European Community.

    Claudio Vitali;Stefano Bombardieri;Haralampos M. Moutsopoulos;Genesio Balestrieri

  • The environment, geo-epidemiology, and autoimmune disease: Rheumatoid arthritis

    Gabriel J. Tobón;Pierre Youinou;Alain Saraux

  • BAFF overexpression is associated with autoantibody production in autoimmune diseases.

    Jacques-Olivier Pers;Capucine Daridon;Valérie Devauchelle;Sandrine Jousse

  • Improvement of Sjögren's syndrome after two infusions of rituximab (anti-CD20).

    Valérie Devauchelle-Pensec;Yvon Pennec;Johanne Morvan;Jacques-Olivier Pers

  • Epigenetics and autoimmunity.

    Wesley H. Brooks;Christelle Le Dantec;Jacques-Olivier Pers;Pierre Youinou

  • Contribution of salivary gland ultrasonography to the diagnosis of Sjögren's syndrome: toward new diagnostic criteria?

    Divi Cornec;Sandrine Jousse-Joulin;Jacques-Olivier Pers;Thierry Marhadour

  • The binding of some human antiendothelial cell antibodies induces endothelial cell apoptosis.

    A Bordron;M Dueymes;Y Levy;C Jamin

  • Prevalence of rheumatoid arthritis and spondyloarthropathy in Brittany, France. Société de Rhumatologie de l'Ouest.

    A Saraux;C Guedes;J Allain;V Devauchelle

  • Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome.

    Capucine Daridon;Valérie Devauchelle;Pascal Hutin;Rozenn Le Berre

  • Ability of the American College of Rheumatology 1987 criteria to predict rheumatoid arthritis in patients with early arthritis and classification of these patients two years later.

    Alain Saraux;Jean M. Berthelot;Gérard Chalès;Catherine Le Henaff

  • BAFF‐modulated repopulation of B lymphocytes in the blood and salivary glands of RITUXIMAB‐TREATED patients with Sjögren's syndrome

    Jacques-Olivier Pers;Valérie Devauchelle;Capucine Daridon;Boutahar Bendaoud

  • CD5 expression in human B-cell populations

    Pierre Youinou;Christophe Jamin;Peter M Lydyard

  • Chronic lymphocytic leukemic (CLL) cells secrete multispecific autoantibodies.

    Barbara M. Bröker;Adek Klajman;Pierre Youinou;Jean Jouquan

  • What is the contents of the magic draft IVIg

    Jean-François Seite;Yehuda Shoenfeld;Pierre Youinou;Sophie Hillion

  • Human T cells induce their own regulation through activation of B cells.

    Sébastien Lemoine;Ahsen Morva;Pierre Youinou;Christophe Jamin

  • IL-6 Modulates CD5 Expression in B Cells from Patients with Lupus by Regulating DNA Methylation

    Soizic Garaud;Christelle Le Dantec;Sandrine Jousse-Joulin;Catherine Hanrotel-Saliou

  • Ectopic Germinal Centers Are Rare in Sjögren’s Syndrome Salivary Glands and Do Not Exclude Autoreactive B Cells

    Laëtitia Le Pottier;Valérie Devauchelle;Alain Fautrel;Capucine Daridon

  • Anti–TNF-α Immunotherapy Is Associated With Increased Gingival Inflammation Without Clinical Attachment Loss in Subjects With Rheumatoid Arthritis

    Jacques-Olivier Pers;Alain Saraux;Roselyne Pierre;Pierre Youinou

  • IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes.

    Jean-François Séïté;Divi Cornec;Yves Renaudineau;Pierre Youinou

  • Tyrosinase as an autoantigen in patients with vitiligo

    E. Baharav;O. Merimski;Y. Shoenfeld;R. Zigelman

Frequent Co-Authors

Alain Saraux
Alain Saraux University of Western Brittany
Yves Renaudineau
Yves Renaudineau University of Western Brittany
Jacques-Olivier Pers
Jacques-Olivier Pers University of Western Brittany
Yehuda Shoenfeld
Yehuda Shoenfeld Sheba Medical Center
Peter M. Lydyard
Peter M. Lydyard University College London
Haralampos M. Moutsopoulos
Haralampos M. Moutsopoulos National and Kapodistrian University of Athens
Sylviane Muller
Sylviane Muller University of Strasbourg
Peter D. Katsikis
Peter D. Katsikis Erasmus University Rotterdam
Jean-Charles Piette
Jean-Charles Piette Sorbonne University
Pier Luigi Meroni
Pier Luigi Meroni Istituto Auxologico Italiano

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