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Molecular Biology

D-Index
45
Citations
11889
World Ranking
2836
National Ranking
1359

Overview

Edwin R. Smith is affiliated with Northwestern University in the United States and has an extensive publication record within the field of Medicine, with a specialized focus on Nephrology. Their research encompasses multiple intersecting areas including Molecular Biology, Surgery, Genetics, and Hematology.

The scientist has contributed to the advancement of knowledge in key topics such as Parathyroid Disorders and Treatments, Dialysis and Renal Disease Management, Pancreatitis Pathology and Treatment, Iron Metabolism and Disorders, Magnesium in Health and Disease, Alkaline Phosphatase Research Studies, and Chronic Kidney Disease and Diabetes.

Recent publications by Edwin R. Smith include:

  • A Randomized Trial on the Effect of Phosphate Reduction on Vascular End Points in CKD (2020), Journal of the American Society of Nephrology
  • Interventions To Attenuate Vascular Calcification Progression in Chronic Kidney Disease: A Systematic Review of Clinical Trials (2022), Journal of the American Society of Nephrology
  • Mud in the blood: the role of protein-mineral complexes and extracellular vesicles in biomineralisation and calcification (2020), Journal of Structural Biology
  • A Metabolic Reprogramming of Glycolysis and Glutamine Metabolism Is a Requisite for Renal Fibrogenesis-Why and How? (2021), Frontiers in Physiology
  • Calciprotein particles: mineral behaving badly? (2020), Current Opinion in Nephrology & Hypertension

Edwin R. Smith often collaborates with several coauthors across their projects. Frequent coauthors include:

  • Tim D. Hewitson
  • S. Holt
  • Nigel D. Toussaint
  • Andreas Pasch
  • Daniel Cejka

The scholar's work is predominantly published in established journals such as:

  • Journal of the American Society of Nephrology
  • Kidney International Reports
  • Kidney International
  • BMC Nephrology
  • Nephrology Dialysis Transplantation

In addition to journal articles, Edwin R. Smith has contributed to book publications. One known contribution is to a volume published by Springer Science+Business Media titled Kidney Research (2023).

Best Publications

  • Covalent modifications of histones during development and disease pathogenesis.

    Sukesh R Bhaumik;Edwin Smith;Ali Shilatifard

  • Physical Association and Coordinate Function of the H3 K4 Methyltransferase MLL1 and the H4 K16 Acetyltransferase MOF

    Yali Dou;Thomas A. Milne;Thomas A. Milne;Alan J. Tackett;Edwin R. Smith

  • The language of histone crosstalk.

    Jung Shin Lee;Edwin Smith;Ali Shilatifard

  • AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

    Chengqi Lin;Edwin R. Smith;Hidehisa Takahashi;Ka Chun Lai

  • Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

    Pengfei Wang;Chengqi Lin;Edwin R. Smith;Hong Guo

  • The drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation.

    Edwin R. Smith;Edwin R. Smith;Antonio Pannuti;Weigang Gu;Arnd Steurnagel

  • ESA1 is a histone acetyltransferase that is essential for growth in yeast

    E. R. Smith;A. Eisen;Weigang Gu;M. Sattah

  • The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

    Deqing Hu;Xin Gao;Marc A. Morgan;Hans Martin Herz

  • Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors

    Hidehisa Takahashi;Tari J. Parmely;Shigeo Sato;Chieri Tomomori-Sato

  • The super elongation complex (SEC) and MLL in development and disease.

    Edwin Smith;Chengqi Lin;Ali Shilatifard

  • A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16

    Edwin R. Smith;Christelle Cayrou;Rong Huang;William S. Lane

  • Born to run: control of transcription elongation by RNA polymerase II

    Fei Xavier Chen;Edwin R. Smith;Ali Shilatifard

  • Enhancer biology and enhanceropathies

    Edwin Smith;Ali Shilatifard

  • Involvement of human MOF in ATM function

    Arun Gupta;Girdhar G. Sharma;Charles S H Young;Manjula Agarwal

  • The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes

    Edwin Smith;Ali Shilatifard

  • PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II.

    Fei Xavier Chen;Ashley R. Woodfin;Alessandro Gardini;Ryan A. Rickels

  • The COMPASS family of H3K4 methylases in Drosophila

    Man Mohan;Hans Martin Herz;Edwin R. Smith;Ying Zhang

  • Linking global histone acetylation to the transcription enhancement of X-chromosomal genes in Drosophila males.

    Edwin R. Smith;Edwin R. Smith;C. David Allis;John C. Lucchesi

  • Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

    Ryan Rickels;Hans Martin Herz;Christie C. Sze;Kaixiang Cao

  • Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing

    Kaiwei Liang;Xin Gao;Joshua M. Gilmore;Laurence Florens

Frequent Co-Authors

Ali Shilatifard
Ali Shilatifard Northwestern University
Michael P. Washburn
Michael P. Washburn University of Kansas
Laurence Florens
Laurence Florens Stowers Institute for Medical Research
Robb Krumlauf
Robb Krumlauf Stowers Institute for Medical Research
Joel C. Eissenberg
Joel C. Eissenberg Saint Louis University
Ramin Shiekhattar
Ramin Shiekhattar University of Miami
Ronald C. Conaway
Ronald C. Conaway The University of Texas Southwestern Medical Center
Joan Weliky Conaway
Joan Weliky Conaway The University of Texas Southwestern Medical Center
C. David Allis
C. David Allis Rockefeller University
Selene K. Swanson
Selene K. Swanson Stowers Institute for Medical Research

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