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D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
16586
World Ranking
9562
National Ranking
4221

Overview

Kai Ge is affiliated with the National Institutes of Health in the United States. Their research primarily lies within the fields of Biochemistry, Genetics, and Molecular Biology, with 117 publications contributing to these disciplines. Additionally, they have contributed to Medicine through 47 publications. Their work spans several subfields, notably Molecular Biology, Cancer Research, Immunology, Physiology, and Oncology.

The scientific topics frequently addressed by Kai Ge include Epigenetics and DNA Methylation, RNA modifications and cancer, Protein Degradation and Inhibitors, Cancer-related gene regulation, Adipose Tissue and Metabolism, Chromatin Remodeling and Cancer, and Ubiquitin and proteasome pathways.

Kai Ge has published numerous recent papers in high-profile journals. These include:

  • Opposing Functions of BRD4 Isoforms in Breast Cancer, 2020, Molecular Cell
  • Lysine Demethylase KDM6A in Differentiation, Development, and Cancer, 2020, Molecular and Cellular Biology
  • MLL4 mediates differentiation and tumor suppression through ferroptosis, 2021, Science Advances
  • JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment, 2022, Science
  • Interplay of BAF and MLL4 promotes cell type-specific enhancer activation, 2021, Nature Communications

The venues where Kai Ge frequently publishes include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancer Research, Journal of Biological Chemistry, and Research Square.

The researcher collaborates regularly with fellow scientists. Their most frequent co-authors are:

  • Ji-Eun Lee
  • Guojia Xie
  • Young-Kwon Park
  • Weiqun Peng
  • Nhien Tran

Best Publications

  • Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation

    Qihuang Jin;Li Rong Yu;Lifeng Wang;Zhijing Zhang

  • Replication fork stability confers chemoresistance in BRCA-deficient cells

    Arnab Ray Chaudhuri;Elsa Callen;Xia Ding;Ewa Gogola

  • Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases

    SunHwa Hong;Young-Wook Cho;Li-Rong Yu;Hong Yu

  • PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex

    Young Wook Cho;Teresa Hong;Sun Hwa Hong;Hong Guo

  • Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

    Pengfei Wang;Chengqi Lin;Edwin R. Smith;Hong Guo

  • H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

    Ji Eun Lee;Chaochen Wang;Shiliyang Xu;Shiliyang Xu;Young-Wook Cho

  • Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis

    Jiyuan Zhang;David Dominguez-Sola;David Dominguez-Sola;Shafinaz Hussein;Ji-Eun Lee

  • The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.

    Ana Ortega-Molina;Isaac W. Boss;Andres Canela;Heng Pan

  • Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis

    Kai Ge;Mohamed Guermah;Chao-Xing Yuan;Chao-Xing Yuan;Mitsuhiro Ito

  • 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions

    Elsa Callen;Michela Di Virgilio;Michael J. Kruhlak;Maria Nieto-Soler

  • H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation

    Gangqing Hu;Kairong Cui;Daniel Northrup;Chengyu Liu

  • Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor γ Isoforms

    Elisabetta Mueller;Stavit Drori;Anita Aiyer;Junming Yie

  • Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis.

    Lifeng Wang;Qihuang Jin;Ji-Eun Lee;I-hsin Su;I-hsin Su

  • Histone H3 lysine 4 methyltransferase KMT2D.

    Eugene Froimchuk;Younghoon Jang;Kai Ge

  • Spatial Clustering for Identification of ChIP-Enriched Regions (SICER) to Map Regions of Histone Methylation Patterns in Embryonic Stem Cells

    Shiliyang Xu;Sean Grullon;Sean Grullon;Kai Ge;Weiqun Peng

  • Identification of H3K4me1-associated proteins at mammalian enhancers.

    Andrea Local;Hui Huang;Hui Huang;Claudio P Albuquerque;Namit Singh

  • UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

    Shayesta Seenundun;Shravanti Rampalli;Qi-Cai Liu;Arif Aziz

  • Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis.

    Ji-Eun Lee;Kai Ge

  • p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation

    Shravanti Rampalli;LiFang Li;Esther Mak;Kai Ge

  • This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Thislicensedoesnot permit commercial exploitation without specific permission.

    Shayesta Seenundun;Qi-Cai Liu;Arif Aziz;Carmen Palii

Frequent Co-Authors

Xinyuan Liu
Xinyuan Liu Southern University of Science and Technology
André Nussenzweig
André Nussenzweig National Institutes of Health
Robert G. Roeder
Robert G. Roeder Rockefeller University
Bing Ren
Bing Ren New York Genome Center
F. Jeffrey Dilworth
F. Jeffrey Dilworth University of Wisconsin–Madison
Vittorio Sartorelli
Vittorio Sartorelli National Institutes of Health
Keji Zhao
Keji Zhao National Institutes of Health
Elsa Callen
Elsa Callen National Institutes of Health
Oksana Gavrilova
Oksana Gavrilova National Institutes of Health
Terry Magnuson
Terry Magnuson University of North Carolina at Chapel Hill

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