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Biology and Biochemistry

D-Index
75
Citations
24392
World Ranking
5242
National Ranking
2494

Overview

H. Rex Gaskins is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Within these broader disciplines, their work emphasizes subfields such as Molecular Biology, Physiology, Oncology, Surgery, and Public Health, Environmental and Occupational Health.

Their research focuses on a range of topics connected to human health and disease, especially involving the gut microbiota and its relationship with health outcomes. Major topics of their work include:

  • Gut microbiota and health
  • Drug Transport and Resistance Mechanisms
  • Diet and metabolism studies
  • Nutritional Studies and Diet
  • Liver Disease Diagnosis and Treatment
  • Pharmacogenetics and Drug Metabolism
  • Pediatric Hepatobiliary Diseases and Treatments

Their frequent publication venues reflect contributions to both preprint and peer-reviewed scientific outlets. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Developments in Nutrition
  • Cancer Epidemiology Biomarkers & Prevention
  • Gastroenterology
  • Research Square (Research Square)

Among recent published papers, notable works include:

  • "Another renaissance for bile acid gastrointestinal microbiology," published in 2024 in Nature Reviews Gastroenterology & Hepatology
  • "Diversity and distribution of sulfur metabolic genes in the human gut microbiome and their association with colorectal cancer," published in 2022 in Microbiome
  • "Completion of the gut microbial epi-bile acid pathway," published in 2021 in Gut Microbes
  • "Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes," published in 2022 in Gut Microbes
  • "The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology," published in 2023 in Journal of Lipid Research

Collaboration is a notable aspect of their career with frequent co-authors including Jason M. Ridlon, Patricia G. Wolf, Lisa Tussing-Humphreys, Ece Mutlu, and Karthik Anantharaman.

Best Publications

  • Developmental microbial ecology of the neonatal gastrointestinal tract

    Roderick I Mackie;Abdelghani Sghir;H Rex Gaskins

  • Habitat degradation impacts black howler monkey ( Alouatta pigra ) gastrointestinal microbiomes

    Katherine R Amato;Carl J Yeoman;Carl J Yeoman;Angela Kent;Nicoletta Righini

  • Fat, fibre and cancer risk in African Americans and rural Africans

    Stephen J. D. O’Keefe;Jia V. Li;Leo Lahti;Junhai Ou

  • Molecular ecological analysis of the gastrointestinal microbiota: a review.

    Erwin G. Zoetendal;Chad T. Collier;Satoshi Koike;Roderick Ian Mackie

  • Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans

    Junhai Ou;Franck Carbonero;Erwin G. Zoetendal;James P. DeLany

  • New scientific paradigms for probiotics and prebiotics.

    Gregor Reid;M E Sanders;H Rex Gaskins;Glenn R Gibson

  • Cross-Talk between Probiotic Bacteria and the Host Immune System

    Blaise Corthésy;H Rex Gaskins;Annick Mercenier

  • Microbial pathways in colonic sulfur metabolism and links with health and disease.

    Franck Carbonero;Ann C. Benefiel;Amir H. Alizadeh-Ghamsari;H. Rex Gaskins

  • Evidence That Hydrogen Sulfide Is a Genotoxic Agent

    Matias S. Attene-Ramos;Elizabeth D. Wagner;Michael J. Plewa;H. Rex Gaskins

  • Application of denaturant gradient gel electrophoresis for the analysis of the porcine gastrointestinal microbiota

    Joyce M. Simpson;Vance J. McCracken;Bryan A White;H Rex Gaskins

  • The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency.

    M Prochazka;H R Gaskins;L D Shultz;E H Leiter

  • NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse.

    K Hamaguchi;H R Gaskins;E H Leiter

  • Relationship Between Microbiota of the Colonic Mucosa vs Feces and Symptoms, Colonic Transit, and Methane Production in Female Patients With Chronic Constipation

    Gopanandan Parthasarathy;Jun Chen;Xianfeng Chen;Nicholas Chia

  • Commensal bacteria, redox stress, and colorectal cancer: mechanisms and models.

    Mark M. Huycke;H. Rex Gaskins

  • Hydrogen sulfide induces direct radical-associated DNA damage.

    Matias S. Attene-Ramos;Elizabeth D. Wagner;H. Rex Gaskins;Michael J. Plewa

  • Voluntary and forced exercise differentially alters the gut microbiome in C57BL/6J Mice

    Jacob M. Allen;Margret E. Berg Miller;Brandt D. Pence;Keith Whitlock

  • Denaturing Gradient Gel Electrophoresis Analysis of 16S Ribosomal DNA Amplicons To Monitor Changes in Fecal Bacterial Populations of Weaning Pigs after Introduction of Lactobacillus reuteri Strain MM53

    Joyce M. Simpson;Vance J. McCracken;H. Rex Gaskins;Roderick I. Mackie

  • Contributions of the microbial hydrogen economy to colonic homeostasis.

    Franck Carbonero;Ann C. Benefiel;H. Rex Gaskins

  • Taurocholic acid metabolism by gut microbes and colon cancer.

    Jason M. Ridlon;Patricia G. Wolf;H. Rex Gaskins

  • Gut Microbiome of Coexisting BaAka Pygmies and Bantu Reflects Gradients of Traditional Subsistence Patterns

    Andres Gomez;Klara J. Petrzelkova;Michael B. Burns;Carl J. Yeoman

Frequent Co-Authors

Paul J. A. Kenis
Paul J. A. Kenis University of Illinois at Urbana-Champaign
Roderick I. Mackie
Roderick I. Mackie University of Illinois at Urbana-Champaign
Steven R. Leigh
Steven R. Leigh University of Colorado Boulder
Bart Deplancke
Bart Deplancke École Polytechnique Fédérale de Lausanne
Lawrence B. Schook
Lawrence B. Schook University of Illinois at Urbana-Champaign
Bryan A. White
Bryan A. White University of Illinois at Urbana-Champaign
Brenda A. Wilson
Brenda A. Wilson University of Illinois at Urbana-Champaign
Karen E. Nelson
Karen E. Nelson J. Craig Venter Institute
Brendan A.C. Harley
Brendan A.C. Harley University of Illinois at Urbana-Champaign
Erwin G. Zoetendal
Erwin G. Zoetendal Wageningen University & Research

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