D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 65 Citations 17,031 111 World Ranking 1070 National Ranking 563

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Transcription factor

Vittorio Sartorelli spends much of his time researching MyoD, Molecular biology, Cell biology, Myogenesis and PCAF. His research in MyoD focuses on subjects like Myogenin, which are connected to Embryonic stem cell and Three prime untranslated region. His research integrates issues of Chromatin, Regulation of gene expression and Transcriptional regulation in his study of Molecular biology.

The various areas that Vittorio Sartorelli examines in his Cell biology study include Genetics, Enhancer, Enhancer RNAs, Gene expression and P300-CBP Transcription Factors. The Myogenesis portion of his research involves studies in Myocyte and Skeletal muscle. His work focuses on many connections between PCAF and other disciplines, such as Acetyltransferases, that overlap with his field of interest in Histone acetyltransferase activity, Microinjection, Multiprotein complex and Histone acetyltransferase.

His most cited work include:

  • Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt (611 citations)
  • Sir2 Regulates Skeletal Muscle Differentiation as a Potential Sensor of the Redox State (529 citations)
  • The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation (497 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Molecular biology, Transcription factor, MyoD and Cellular differentiation. His Cell biology study combines topics in areas such as Chromatin, Gene expression, Epigenetics and Skeletal muscle. Vittorio Sartorelli has researched Molecular biology in several fields, including Multiprotein complex, Chromatin immunoprecipitation, EZH2 and Serum response factor, Transcription.

Within one scientific family, Vittorio Sartorelli focuses on topics pertaining to Regulation of gene expression under Transcription factor, and may sometimes address concerns connected to Transcriptional regulation and Cancer research. His MyoD study is associated with Myogenesis. Vittorio Sartorelli focuses mostly in the field of Cellular differentiation, narrowing it down to topics relating to Embryonic stem cell and, in certain cases, microRNA.

He most often published in these fields:

  • Cell biology (49.14%)
  • Molecular biology (33.62%)
  • Transcription factor (26.72%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (49.14%)
  • Chromatin (18.10%)
  • Gene (10.34%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Chromatin, Gene, Skeletal muscle and Enhancer. Vittorio Sartorelli interconnects Embryonic stem cell, Reprogramming, Epigenetics and Cellular differentiation in the investigation of issues within Cell biology. His biological study focuses on MyoD.

Vittorio Sartorelli combines subjects such as BET inhibitor, Homeostasis, Cancer cachexia, Quiescent state and Myocyte with his study of Skeletal muscle. His biological study spans a wide range of topics, including Regulation of gene expression, Innate lymphoid cell, Computational biology and Histone. His Regulation of gene expression research includes themes of Transcription factor and Transcription.

Between 2013 and 2021, his most popular works were:

  • The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells (282 citations)
  • Super-enhancers delineate disease-associated regulatory nodes in T cells (232 citations)
  • Metabolic Reprogramming of Stem Cell Epigenetics (144 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Transcription factor

Cell biology, Regulation of gene expression, Stem cell, Myocyte and Genetics are his primary areas of study. His Cell biology research includes elements of Enhancer, Gene silencing, RNA-binding protein and IL-2 receptor. His study in Regulation of gene expression is interdisciplinary in nature, drawing from both Peroxisome proliferator-activated receptor, EZH2, Cellular differentiation and Embryoid body.

His Stem cell research also works with subjects such as

  • Reprogramming, which have a strong connection to Regenerative medicine, Somatic cell, Induced pluripotent stem cell, Histone deacetylase and Sirtuin 1,
  • Epigenetics that connect with fields like Embryonic stem cell. He studies Myogenesis which is a part of Myocyte. In the subject of general Biochemistry, his work in MyoD Protein, Mitochondrial biogenesis, MyoD and Myogenin is often linked to PITX2, thereby combining diverse domains of study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

Marcella Fulco;Yana Cen;Po Zhao;Eric P. Hoffman.
Developmental Cell (2008)

808 Citations

Sir2 Regulates Skeletal Muscle Differentiation as a Potential Sensor of the Redox State

Marcella Fulco;R.Louis Schiltz;Simona Iezzi;M.Todd King.
Molecular Cell (2003)

717 Citations

The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

Giuseppina Caretti;Monica Di Padova;Bruce Micales;Gary E. Lyons.
Genes & Development (2004)

670 Citations

twist is a potential oncogene that inhibits apoptosis

Roberta Maestro;Angelo P. Dei Tos;Yasuo Hamamori;Svetlana Krasnokutsky.
Genes & Development (1999)

642 Citations

Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

Pier Lorenzo Puri;Pier Lorenzo Puri;Vittorio Sartorelli;Vittorio Sartorelli;Xiang Jiao Yang;Yasuo Hamamori.
Molecular Cell (1997)

509 Citations

Regulation of Histone Acetyltransferases p300 and PCAF by the bHLH Protein Twist and Adenoviral Oncoprotein E1A

Yasuo Hamamori;Vittorio Sartorelli;Vasily Ogryzko;Pier Lorenzo Puri;Pier Lorenzo Puri.
Cell (1999)

478 Citations

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C.

V Sartorelli;J Huang;Y Hamamori;L Kedes.
Molecular and Cellular Biology (1997)

452 Citations

eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci

Kambiz Mousavi;Hossein Zare;Stefania Dell’Orso;Lars Grontved.
Molecular Cell (2013)

448 Citations

Regulation of the p300 HAT domain via a novel activation loop

Paul R Thompson;Paul R Thompson;Dongxia Wang;Ling Wang;Marcella Fulco.
Nature Structural & Molecular Biology (2004)

443 Citations

Acetylation of MyoD Directed by PCAF Is Necessary for the Execution of the Muscle Program

Vittorio Sartorelli;Pier Lorenzo Puri;Pier Lorenzo Puri;Yasuo Hamamori;Vasily Ogryzko.
Molecular Cell (1999)

431 Citations

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