D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 66 Citations 17,955 116 World Ranking 1801 National Ranking 922

Research.com Recognitions

Awards & Achievements

1976 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of investigation include Molecular biology, Actin, Gene, Cell biology and Gene expression. The various areas that Larry Kedes examines in his Molecular biology study include Complementary DNA, Messenger RNA, Untranslated region, Regulation of gene expression and Transcription. His work carried out in the field of Complementary DNA brings together such families of science as Nucleic acid sequence and Beta-actin.

His study in Actin is interdisciplinary in nature, drawing from both Myosin and Skeletal muscle. The Hes3 signaling axis, Notch proteins, Notch signaling pathway and MyoD Protein research Larry Kedes does as part of his general Cell biology study is frequently linked to other disciplines of science, such as PITX2, therefore creating a link between diverse domains of science. His biological study spans a wide range of topics, including Xenopus, Histone and Chromosome 7.

His most cited work include:

  • HES and HERP families: multiple effectors of the Notch signaling pathway. (1022 citations)
  • Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed. (1016 citations)
  • Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA (844 citations)

What are the main themes of his work throughout his whole career to date?

Larry Kedes mainly investigates Molecular biology, Gene, Cell biology, Gene expression and Actin. The study incorporates disciplines such as Transcription factor, Complementary DNA, Skeletal muscle, Regulation of gene expression and Transcription in addition to Molecular biology. Gene is a primary field of his research addressed under Genetics.

His work deals with themes such as Internal medicine, Biochemistry and Gene isoform, which intersect with Cell biology. His biological study deals with issues like Messenger RNA, which deal with fields such as Sea urchin. His studies in Actin integrate themes in fields like Myofibril, C2C12 and Cytoskeleton.

He most often published in these fields:

  • Molecular biology (50.32%)
  • Gene (29.03%)
  • Cell biology (30.32%)

What were the highlights of his more recent work (between 1998-2013)?

  • Cell biology (30.32%)
  • Molecular biology (50.32%)
  • Internal medicine (14.19%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Molecular biology, Internal medicine, Notch signaling pathway and Transcription factor. The Cell biology study combines topics in areas such as Serum response factor and Receptor. His Molecular biology research includes themes of Retrovirus, Chromatin and Adenoviridae, Genetic enhancement, Gene delivery.

His Internal medicine research is multidisciplinary, incorporating perspectives in Endocrinology, Oncology and Cardiology. His Notch signaling pathway research integrates issues from BMPR2 and SMAD. His Transcription factor research is multidisciplinary, relying on both Regulation of gene expression, DNA binding site and Gene expression.

Between 1998 and 2013, his most popular works were:

  • HES and HERP families: multiple effectors of the Notch signaling pathway. (1022 citations)
  • twist is a potential oncogene that inhibits apoptosis (442 citations)
  • Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. (427 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Larry Kedes focuses on Molecular biology, Notch signaling pathway, Transcription factor, Myocyte and Hes3 signaling axis. His Molecular biology research includes elements of Acetyltransferase, PCAF, Transcription and Transduction. Larry Kedes has researched Transcription factor in several fields, including Carcinogenesis, Regulation of gene expression, Oncogene and Mdm2.

The concepts of his Myocyte study are interwoven with issues in Cellular differentiation, Pathology, Myocardial infarction, Sodium butyrate and Transplantation. His Hes3 signaling axis study introduces a deeper knowledge of Cell biology. His Cell biology research is multidisciplinary, incorporating elements of Chromatin, Histone Acetyltransferases, Transcriptional regulation, N-terminus and Acetyltransferases.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.

P Gunning;P Ponte;H Okayama;J Engel.
Molecular and Cellular Biology (1983)

1633 Citations

HES and HERP families: multiple effectors of the Notch signaling pathway.

Tatsuya Iso;Larry Kedes;Yasuo Hamamori.
Journal of Cellular Physiology (2003)

1435 Citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

Phyllis Ponte;Sun-Yu Ng;Joanne Engel;Peter Gunning.
Nucleic Acids Research (1984)

1094 Citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts

Peter Gunning;John Leavitt;George Muscat;Sun-Yu Ng.
Proceedings of the National Academy of Sciences of the United States of America (1987)

915 Citations

twist is a potential oncogene that inhibits apoptosis

Roberta Maestro;Angelo P. Dei Tos;Yasuo Hamamori;Svetlana Krasnokutsky.
Genes & Development (1999)

620 Citations

Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium.

Jochen Müller-Ehmsen;Peter Whittaker;Robert A. Kloner;Joan S. Dow.
Journal of Molecular and Cellular Cardiology (2002)

561 Citations

Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif

A Minty;L Kedes.
Molecular and Cellular Biology (1986)

534 Citations

Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

Pier Lorenzo Puri;Pier Lorenzo Puri;Vittorio Sartorelli;Vittorio Sartorelli;Xiang Jiao Yang;Yasuo Hamamori.
Molecular Cell (1997)

490 Citations

Evolution of the functional human beta-actin gene and its multi-pseudogene family: conservation of noncoding regions and chromosomal dispersion of pseudogenes.

Sun-Yu Ng;P. Gunning;R. Eddy;P. Ponte.
Molecular and Cellular Biology (1985)

474 Citations

Transplantation of fetal myocardial tissue into the infarcted myocardium of rat. A potential method for repair of infarcted myocardium

J. Leor;M. Patterson;M. J. Quinones;L. H. Kedes.
Circulation (1996)

473 Citations

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