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Biology and Biochemistry

D-Index
69
Citations
11343
World Ranking
7593
National Ranking
3452

Overview

Velia M. Fowler is affiliated with the University of Delaware in the United States and focuses research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several specialized subfields, including Molecular Biology, Physiology, Cell Biology, Pulmonary and Respiratory Medicine, and Radiology, Nuclear Medicine and Imaging.

The main topics of research covered by Velia M. Fowler include:

  • Erythrocyte Function and Pathophysiology
  • Connexins and lens biology
  • Cellular Mechanics and Interactions
  • Blood properties and coagulation
  • Corneal surgery and disorders
  • Lipid Membrane Structure and Behavior
  • Ocular Surface and Contact Lens

Velia M. Fowler has contributed to multiple papers with notable recent publications including:

  • Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation, 2020, PLoS Computational Biology
  • Proteomic and functional analyses of the periodic membrane skeleton in neurons, 2022, Nature Communications
  • Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9-related disease, 2020, Blood
  • The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology, 2020, Human Molecular Genetics
  • Tropomyosin 3.1 Association With Actin Stress Fibers is Required for Lens Epithelial to Mesenchymal Transition, 2020, Investigative Ophthalmology & Visual Science

Frequent co-authors working alongside Velia M. Fowler include Roberta B. Nowak, Arit Ghosh, Justin Parreno, Megan Coffin, and Sadia T. Islam.

The scholar regularly publishes in several scientific venues, most prominently in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cytoskeleton
  • Blood
  • Investigative Ophthalmology & Visual Science
  • Molecular Biology of the Cell

Best Publications

  • Tropomodulin caps the pointed ends of actin filaments.

    A Weber;C R Pennise;G G Babcock;V M Fowler

  • Cell migration without a lamellipodium translation of actin dynamics into cell movement mediated by tropomyosin

    Stephanie L. Gupton;Karen L. Anderson;Thomas P. Kole;Robert S. Fischer

  • A New Function for Adducin CALCIUM/CALMODULIN-REGULATED CAPPING OF THE BARBED ENDS OF ACTIN FILAMENTS

    Philip A. Kuhlman;Christine A. Hughes;Vann Bennett;Velia M. Fowler

  • Spectrin plus band 4.1 cross-link actin. Regulation by micromolar calcium.

    V Fowler;D L Taylor

  • Actin dynamics at pointed ends regulates thin filament length in striated muscle

    Ryan Littlefield;Angels Almenar-Queralt;Velia M. Fowler

  • Erythrocyte membrane tropomyosin. Purification and properties.

    V M Fowler;V Bennett

  • Regulation of actin filament length in erythrocytes and striated muscle

    Velia M Fowler

  • Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes

    Carol C. Gregorio;Annemarie Weber;Meredith Bondad;Cynthia R. Pennise

  • Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: a comparative (re)view on avian sex determination

    I Nanda;E Zend-Ajusch;Z Shan;F Grützner

  • Tropomodulin: a cytoskeletal protein that binds to the end of erythrocyte tropomyosin and inhibits tropomyosin binding to actin.

    Velia M. Fowler

  • Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy

    Michaela Yuen;Sarah A. Sandaradura;James J. Dowling;James J. Dowling;Alla S. Kostyukova

  • Second report on chicken genes and chromosomes 2005

    Michael Schmid;I. Nanda;H. Hoehn;M. Schartl

  • Tropomodulin is associated with the free (pointed) ends of the thin filaments in rat skeletal muscle.

    V M Fowler;M A Sussmann;P G Miller;B E Flucher

  • Identification and purification of a novel Mr 43,000 tropomyosin-binding protein from human erythrocyte membranes.

    V M Fowler

  • Lateral mobility of human erythrocyte integral membrane proteins

    Velia Fowler;Daniel Branton

  • DEFINING ACTIN FILAMENT LENGTH IN STRIATED MUSCLE: Rulers and Caps or Dynamic Stability?

    R Littlefield;V M Fowler

  • The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments.

    Abigail S. McElhinny;Bernhard Kolmerer;Velia M. Fowler;Siegfried Labeit

  • Mechanisms of thin filament assembly in embryonic chick cardiac myocytes: tropomodulin requires tropomyosin for assembly.

    Carol C. Gregorio;Velia M. Fowler

  • Leiomodins: larger members of the tropomodulin (Tmod) gene family.

    Catharine A. Conley;Kimberly L. Fritz-Six;Angels Almenar-Queralt;Velia M. Fowler

  • Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types.

    Sawako Yamashiro;David S. Gokhin;Sumiko Kimura;Roberta B. Nowak

Frequent Co-Authors

Carol C. Gregorio
Carol C. Gregorio University of Arizona
Kathryn N. North
Kathryn N. North University of Melbourne
Mark A. Sussman
Mark A. Sussman San Diego State University
Narla Mohandas
Narla Mohandas New York Blood Center
John H. Hartwig
John H. Hartwig Brigham and Women's Hospital
David A. Williams
David A. Williams Boston Children's Hospital
Monkol Lek
Monkol Lek Yale University
Nigel G. Laing
Nigel G. Laing University of Western Australia
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
Mark J. Daly
Mark J. Daly Massachusetts General Hospital

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