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Immunology

D-Index
71
Citations
20028
World Ranking
2299
National Ranking
88

Overview

Hendrika Bootsma is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily focuses on topics related to salivary gland disorders and functions, with significant contributions in related areas such as salivary gland tumors diagnosis and treatment, systemic lupus erythematosus research, and systemic sclerosis and related diseases.

Their work spans various fields of study within medicine, particularly emphasizing subfields like physiology, rheumatology, surgery, immunology, and pathology and forensic medicine. The integration of these disciplines reflects a comprehensive approach to understanding disease mechanisms and treatment modalities, especially in autoimmune and glandular conditions.

Key topics addressed in their publications include:

  • Salivary Gland Disorders and Functions
  • Salivary Gland Tumors Diagnosis and Treatment
  • Systemic Lupus Erythematosus Research
  • Systemic Sclerosis and Related Diseases
  • Oral Health Pathology and Treatment
  • Spondyloarthritis Studies and Treatments
  • Monoclonal and Polyclonal Antibodies Research

Hendrika Bootsma has contributed to numerous papers, with some notable recent publications including:

  • 2021 DORIS definition of remission in SLE: final recommendations from an international task force (2021, Lupus Science & Medicine)
  • Epithelial-immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis (2021, Nature Reviews Rheumatology)
  • Efficacy and safety of abatacept in active primary Sjögren's syndrome: results of a phase III, randomised, placebo-controlled trial (2020, Annals of the Rheumatic Diseases)
  • A randomized, phase II study of sequential belimumab and rituximab in primary Sjögren's syndrome (2022, JCI Insight)
  • The Transcriptome of Paired Major and Minor Salivary Gland Tissue in Patients With Primary Sjögren's Syndrome (2021, Frontiers in Immunology)

The scientist frequently collaborates with a consistent group of coauthors, including Suzanne Arends, Frans G. M. Kroese, Arjan Vissink, Gwenny M. Verstappen, and Fred K. L. Spijkervet, indicating a collaborative research environment and shared interests in rheumatology and immunological studies.

Hendrika Bootsma's research output is often published in established venues such as Annals of the Rheumatic Diseases, Lara D. Veeken, Clinical and Experimental Rheumatology, PubMed, and The Journal of Rheumatology. These venues reflect a strong connection to rheumatologic and clinical research communities, with an emphasis on peer-reviewed dissemination of findings relevant to autoimmune and salivary gland diseases.

Their extensive publication record in these journals and specialized fields of medicine showcases an ongoing commitment to advancing knowledge in the mechanisms, diagnosis, and treatment of complex autoimmune and glandular conditions.

Best Publications

  • Treat-to-target in systemic lupus erythematosus: recommendations from an international task force

    Ronald van Vollenhoven;Marta Mosca;George Bertsias;David Isenberg

  • Rituximab treatment in patients with primary Sjögren's syndrome: an open-label phase II study.

    J Pijpe;van Gustaaf Imhoff;Frederik Spijkervet;Jan Roodenburg

  • EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide.

    Raphaèle Seror;Simon J Bowman;Pilar Brito-Zeron;Elke Theander

  • Prevention of relapses in systemic lupus erythematosus.

    H. Bootsma;P. Spronk;G. de Boer;P. Limburg

  • A framework for remission in SLE: consensus findings from a large international task force on definitions of remission in SLE (DORIS)

    Ronald van Vollenhoven;Alexandre Voskuyl;George Bertsias;Cynthia Aranow

  • Characterization of systemic disease in primary Sjögren's syndrome: EULAR-SS Task Force recommendations for articular, cutaneous, pulmonary and renal involvements

    Manuel Ramos-Casals;Pilar Brito-Zerón;Raphaèle Seror;Hendrika Bootsma

  • Health-related quality of life, employment and disability in patients with Sjögren's syndrome

    Jiska M. Meijer;Petra M. Meiners;James J. R. Huddleston Slater;Fred K. L. Spijkervet

  • Skewed distribution of IgG Fc receptor IIa (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients

    A J Duits;H Bootsma;R H Derksen;P E Spronk

  • Epithelial-immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis.

    Gwenny M Verstappen;Sarah Pringle;Hendrika Bootsma;Frans G M Kroese

  • Parotid gland biopsy compared with labial biopsy in the diagnosis of patients with primary Sjogren's syndrome

    J. Pijpe;Warner Kalk;J. E. van der Wal;Arjan Vissink

  • CHANGES IN ANTIBODIES TO C1Q PREDICT RENAL RELAPSES IN SYSTEMIC LUPUS-ERYTHEMATOSUS

    Ida E.M. Coremans;Peter E. Spronk;Hendrika Bootsma;Mohamed R. Daha

  • Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium.

    Pilar Brito-Zerón;Pilar Brito-Zerón;Nihan Acar-Denizli;Margit Zeher;Astrid Rasmussen

  • Shared gut, but distinct oral microbiota composition in primary Sjögren's syndrome and systemic lupus erythematosus.

    Taco A. van der Meulen;Hermie J.M. Harmsen;Arnau Vich Vila;Alexander Kurilshikov

  • Levels of soluble VCAM‐1, soluble ICAM‐1, and soluble E‐selectin during disease exacerbations in patients with systemic lupus erythematosus (SLE); a long term prospective study

    P. E. Spronk;H. Bootsma;M. G. Huitema;P. C. Limburg

  • Th17 cells in primary Sjogren's syndrome : Pathogenicity and plasticity

    Gwenny M. Verstappen;Odilia B.J. Corneth;Hendrika Bootsma;Frans G.M. Kroese

  • Attenuation of Follicular Helper T Cell-Dependent B Cell Hyperactivity by Abatacept Treatment in Primary Sjogren's Syndrome

    Gwenny M. Verstappen;Petra M. Meiners;Odilia B. J. Corneth;Annie Visser

  • Is salivary gland ultrasonography a useful tool in Sjögren’s syndrome? A systematic review

    Sandrine Jousse-Joulin;Vera Milic;Malin V Jonsson;Athena Plagou

  • Sialometry and sialochemistry: diagnostic tools for Sjögren's syndrome

    Wwi Kalk;Arjan Vissink;Frederik Spijkervet;Hendrika Bootsma

  • B-cell hyperactivity in primary Sjögren's syndrome

    Franciscus Kroese;Wayel H Abdulahad;Erlin Haacke;Nicolaas A Bos

  • The microbiome-systemic diseases connection

    van der Taco Meulen;Hermie Harmsen;Hendrika Bootsma;Frederik Spijkervet

  • Early diagnosis of primary Sjögren’s syndrome: EULAR-SS task force clinical recommendations

    Pilar Brito-Zerón;Elke Theander;Chiara Baldini;Raphaèle Seror

  • The predictive value of fluctuations in IgM and IgG class anti-dsDNA antibodies for relapses in systemic lupus erythematosus. A prospective long term observation

    H. Bootsma;P.E. Spronk;E.J. Terborg;E.J. Hummel

  • How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project).

    Pilar Brito-Zerón;Nihan Acar-Denizli;Wan-Fai Ng;Margit Zeher

Frequent Co-Authors

Arjan Vissink
Arjan Vissink University Medical Center Groningen
Frans G. M. Kroese
Frans G. M. Kroese University Medical Center Groningen
Elisabeth Brouwer
Elisabeth Brouwer University Medical Center Groningen
Xavier Mariette
Xavier Mariette University of Paris-Saclay
Manuel Ramos-Casals
Manuel Ramos-Casals Hospital Clinic of Barcelona
Michele Bombardieri
Michele Bombardieri Queen Mary University of London
Cees G. M. Kallenberg
Cees G. M. Kallenberg University of Groningen
David A. Isenberg
David A. Isenberg University College London
Damien Sene
Damien Sene Université Paris Cité
Luca Quartuccio
Luca Quartuccio University of Udine

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