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Medicine

D-Index
129
Citations
73976
World Ranking
2556
National Ranking
265

Overview

Christopher P. Denton is affiliated with University College London in the United Kingdom. Their research primarily focuses on topics related to systemic sclerosis and related diseases, interstitial lung diseases and idiopathic pulmonary fibrosis, dermatologic treatments and research, inflammatory myopathies and dermatomyositis, mast cells and histamine, pulmonary hypertension research and treatments, and skin diseases and diabetes.

The primary fields of study where Denton has contributed include Medicine, with significant subfields in pathology and forensic medicine, pulmonary and respiratory medicine, dermatology, epidemiology, and immunology.

Denton frequently publishes in several venues, including the following:

  • Lara D. Veeken
  • Annals of the Rheumatic Diseases
  • Arthritis & Rheumatology
  • Journal of Scleroderma and Related Disorders
  • The Lancet Rheumatology

Their research collaboration network includes frequent co-authors such as:

  • Voon H Ong
  • Yannick Allanore
  • Dinesh Khanna
  • Marco Matucci-Cerinic
  • Oliver Distler

Several recent publications highlight Denton's work, including:

  • "Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial," 2020, The Lancet Respiratory Medicine
  • "Standardisation of nailfold capillaroscopy for the assessment of patients with Raynaud's phenomenon and systemic sclerosis," 2020, Autoimmunity Reviews
  • "Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial," 2022, The Lancet Respiratory Medicine
  • "Predictors of progression in systemic sclerosis patients with interstitial lung disease," 2020, European Respiratory Journal
  • "Definition, classification and diagnosis of pulmonary hypertension," 2024, European Respiratory Journal

Best Publications

  • 2013 classification criteria for systemic sclerosis: An american college of rheumatology/European league against rheumatism collaborative initiative

    Frank Van Den Hoogen;Dinesh Khanna;Jaap Fransen;Sindhu R. Johnson

  • Updated clinical classification of pulmonary hypertension

    Gerald Simonneau;Michael A Gatzoulis;Ian Adatia;David Celermajer

  • Haemodynamic definitions and updated clinical classification of pulmonary hypertension.

    Gérald Simonneau;Gérald Simonneau;David Montani;David Montani;David S. Celermajer;Christopher P. Denton

  • Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

    Anthony J. Tyndall;Bettina Bannert;Madelon Vonk;Paolo Airò

  • Interstitial lung disease in systemic sclerosis: a simple staging system.

    Nicole S. L. Goh;Sujal R. Desai;Srihari Veeraraghavan;David M. Hansell

  • Update of EULAR recommendations for the treatment of systemic sclerosis

    Otylia Kowal-Bielecka;Jaap Fransen;Jerome Avouac;Mike Becker;Mike Becker

  • Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database

    U A Walker;A Tyndall;L Czirják;C Denton

  • Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach

    D Mukerjee;D St George;B Coleiro;C Knight

  • A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma.

    Rachel K Hoyles;Ross W Ellis;Jessica Wellsbury;Belinda Lees

  • Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist.

    J. H. Korn;Maureen D Mayes;M. Matucci Cerinic;M. Rainisio

  • A myocardial lineage derives from Tbx18 epicardial cells

    Chen-Leng Cai;Jody C. Martin;Yunfu Sun;Li Cui

  • Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study

    J Gerry Coghlan;Christopher P Denton;Ekkehard Grünig;Diana Bonderman

  • EULAR recommendations for the treatment of systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group (EUSTAR)

    O. Kowal-Bielecka;R. Landewé;J. Avouac;S. Chwiesko

  • Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial

    Dinesh Khanna;Christopher P Denton;Angelika Jahreis;Jacob M van Laar

  • Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial.

    Dinesh Khanna;Celia J F Lin;Daniel E Furst;Jonathan Goldin

  • Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial

    Marco Matucci-Cerinic;Christopher P Denton;Daniel E Furst;Maureen D Mayes

  • Recombinant human anti-transforming growth factor β1 antibody therapy in systemic sclerosis: A multicenter, randomized, placebo-controlled phase I/II trial of CAT-192

    Christopher P. Denton;Peter A. Merkel;Daniel E. Furst;Dinesh Khanna

  • Scleroderma renal crisis: patient characteristics and long-term outcomes.

    H. Penn;A.J. Howie;E.J. Kingdon;C.C. Bunn

  • Prediction of pulmonary complications and long-term survival in systemic sclerosis.

    Svetlana I. Nihtyanova;Benjamin E. Schreiber;Voon H. Ong;Daniel Rosenberg

  • Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.

    Xu Shi-Wen;Yunliang Chen;Christopher P. Denton;Mark Eastwood

Frequent Co-Authors

David Abraham
David Abraham University College London
Carol M. Black
Carol M. Black University College London
Marco Matucci-Cerinic
Marco Matucci-Cerinic University of Florence
Oliver Distler
Oliver Distler University of Zurich
Dinesh Khanna
Dinesh Khanna University of Michigan–Ann Arbor
Yannick Allanore
Yannick Allanore Université Paris Cité
Ariane L. Herrick
Ariane L. Herrick University of Manchester
Daniel E. Furst
Daniel E. Furst University of California, Los Angeles
Janet E. Pope
Janet E. Pope University of Western Ontario
Ulf Müller-Ladner
Ulf Müller-Ladner University of Giessen

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