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Biology and Biochemistry

D-Index
70
Citations
15230
World Ranking
7115
National Ranking
483

Overview

Renu Wadhwa is affiliated with the National Institute of Advanced Industrial Science and Technology in Japan. Their research spans multiple fields primarily focused on Medicine and Biochemistry, Genetics and Molecular Biology. The scientist has contributed substantially to subfields including Molecular Biology, Complementary and Alternative Medicine, Oncology, Infectious Diseases, and Insect Science.

Their main research topics cover:

  • Phytochemicals and Medicinal Plants
  • PARP inhibition in cancer therapy
  • SARS-CoV-2 and COVID-19 Research
  • Medicinal Plants and Neuroprotection
  • Cell death mechanisms and regulation
  • Bee Products Chemical Analysis
  • Heat shock proteins research

Among recent publications by Renu Wadhwa are:

  • "Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells", 2020, Journal of Biomolecular Structure and Dynamics
  • "Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity", 2020, Journal of Biomolecular Structure and Dynamics
  • "Experimental Evidence for Therapeutic Potentials of Propolis", 2021, Nutrients
  • "Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes", 2020, Nature Communications
  • "Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action", 2020, Cancers

Frequent coauthors collaborating with Renu Wadhwa include:

  • Sunil C. Kaul
  • Durai Sundar
  • Vipul Kumar
  • Jaspreet Kaur Dhanjal
  • Anissa Nofita Sari

Renu Wadhwa's work has been published repeatedly in several scientific venues with the highest number of publications in:

  • Cancers
  • Current Topics in Medicinal Chemistry
  • Journal of Biomolecular Structure and Dynamics
  • International Journal of Molecular Sciences
  • Scientific Reports

Best Publications

  • Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

    Teruaki Nomura;Matiullah Khan;Sunil C. Kaul;Hai Dong Dong

  • An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where?

    Renu Wadhwa;Kazunari Taira;Sunil C. Kaul

  • Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.

    Renu Wadhwa;Syuichi Takano;Kamaljit Kaur;Custer C. Deocaris;Custer C. Deocaris

  • Selective Toxicity of MKT-077 to Cancer Cells Is Mediated by Its Binding to the hsp70 Family Protein mot-2 and Reactivation of p53 Function

    Renu Wadhwa;Takashi Sugihara;Akiko Yoshida;Hitoshi Nomura

  • Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member

    Renu Wadhwa;Syuichi Takano;Martin Robert;Akiko Yoshida

  • The Ski Protein Family Is Required for MeCP2-mediated Transcriptional Repression

    Kenji Kokura;Sunil C. Kaul;Renu Wadhwa;Teruaki Nomura

  • Proteomic Identification of a Stress Protein, Mortalin/mthsp70/GRP75 Relevance To Parkinson Disease

    Jinghua Jin;Christine Hulette;Yan Wang;Terry Zhang

  • On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60.

    Custer C. Deocaris;Sunil C. Kaul;Renu Wadhwa;Renu Wadhwa

  • Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype.

    R Wadhwa;S C Kaul;Y Ikawa;Y Sugimoto

  • Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein.

    Renu Wadhwa;Tomoko Yaguchi;Md.K. Hasan;Youji Mitsui

  • Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect.

    Nashi Widodo;Kamaljit Kaur;Bhupal G. Shrestha;Yasuomi Takagi

  • Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75.

    Qitao Ran;Renu Wadhwa;Rena Kawai;Sunil C. Kaul

  • Disruption of Telomere Maintenance by Depletion of the MRE11/RAD50/NBS1 Complex in Cells That Use Alternative Lengthening of Telomeres

    Ze-Huai Zhong;Wei-Qin Jiang;Anthony J. Cesare;Axel A. Neumann

  • Protective Role of Ashwagandha Leaf Extract and Its Component Withanone on Scopolamine-Induced Changes in the Brain and Brain-Derived Cells

    Arpita Konar;Navjot Shah;Rumani Singh;Nishant Saxena

  • Quantum dots in bio-imaging: Revolution by the small

    Harinder Arya;Zeenia Kaul;Renu Wadhwa;Kazunari Taira

  • Role of PML and PML-RARα in Mad-Mediated Transcriptional Repression

    Matiullah Khan;Teruaki Nomura;Hyungtae Kim;Sunil C. Kaul

  • Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates.

    Zeenia Kaul;Tomoko Yaguchi;Sunil C Kaul;Takashi Hirano

  • Mortalin–p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy

    W-J Lu;N P Lee;S C Kaul;F Lan

  • Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling

    Nashi Widodo;Didik Priyandoko;Didik Priyandoko;Navjot Shah;Navjot Shah;Renu Wadhwa

  • The Ski Protein Family Is Required for MeCP2-mediated

    Kenji Kokura;Sunil C. Kaul;Renu Wadhwa;Teruaki Nomura

Frequent Co-Authors

Sunil C. Kaul
Sunil C. Kaul National Institute of Advanced Industrial Science and Technology
Youji Mitsui
Youji Mitsui Tokushima Bunri University
Kazunari Taira
Kazunari Taira University of Tokyo
Roger R. Reddel
Roger R. Reddel Children's Medical Research Institute
Chae-Ok Yun
Chae-Ok Yun Hanyang University
Tetsuro Ishii
Tetsuro Ishii University of Tsukuba
Yoshikazu Sugimoto
Yoshikazu Sugimoto Keio University
Makoto Miyagishi
Makoto Miyagishi National Institute of Advanced Industrial Science and Technology
Pratap Kumar Pati
Pratap Kumar Pati Guru Nanak Dev University

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