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D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
20714
World Ranking
5896
National Ranking
183

Overview

Zhihua Liu is affiliated with Peking Union Medical College Hospital in China. Their research encompasses diverse areas within biochemistry, genetics, molecular biology, and medicine, with a particular focus on oncology and cancer research. This scholar's work covers notable subfields such as molecular biology, oncology, cancer research, biomedical engineering, and immunology.

Their research themes concentrate on specific topics including RNA modifications and cancer, cancer-related gene regulation, epigenetics and DNA methylation, cancer immunotherapy and biomarkers, esophageal cancer research and treatment, ubiquitin and proteasome pathways, and cancer-related molecular mechanisms research.

Zhihua Liu has contributed to multiple publications in various esteemed journals. Frequent publication venues include:

  • Cancer Letters
  • SSRN Electronic Journal
  • Signal Transduction and Targeted Therapy
  • Nature Communications
  • Cancer Cell

Among their recent papers are:

  • Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer, 2021, Cancer Cell
  • Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial, 2022, Cancer Cell
  • Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma, 2020, Cell Research
  • Multifunctional Graphdiyne-Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer, 2021, Advanced Materials
  • Cross-tissue human fibroblast atlas reveals myofibroblast subtypes with distinct roles in immune modulation, 2024, Cancer Cell

Zhihua Liu frequently collaborates with several co-authors, including:

  • Hongyan Chen
  • Aiping Luo
  • Yahui Zhao
  • Xiaowei Wu
  • Qingyu Luo

Their scientific output amounts to a substantial number of publications, especially in molecular biology and medicine, involving 236 and 140 papers respectively. The body of work reflects an interdisciplinary approach, combining insights from molecular biology, immunology, biomedical engineering, and clinical oncology.

This extensive research portfolio indicates an emphasis on understanding cancer mechanisms at the molecular and cellular level, with applications in immunotherapy and treatment strategies, particularly concerning esophageal and other cancers.

Best Publications

  • Identification of genomic alterations in oesophageal squamous cell cancer

    Yongmei Song;Lin Li;Yunwei Ou;Zhibo Gao

  • Epidemiology and Prevention of Hepatitis B Virus Infection.

    Jinlin Hou;Zhihua Liu;Fan Gu

  • Risk factors and mechanism of transplacental transmission of hepatitis B virus: a case-control study.

    De-Zhong Xu;Yong-Ping Yan;Bernard C.K. Choi;Jian-Qiu Xu

  • Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer.

    Yuanyuan Zhang;Hongyan Chen;Hongnan Mo;Xueda Hu

  • MicroRNA-10b Promotes Migration and Invasion through KLF4 in Human Esophageal Cancer Cell Lines

    Yanyan Tian;Aiping Luo;Yiran Cai;Qin Su

  • Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations

    Chen Wu;Zhibin Hu;Zhonghu He;Weihua Jia

  • Identification of Functional Genetic Variants in Cyclooxygenase-2 and Their Association With Risk of Esophageal Cancer

    Xuemei Zhang;Xuemei Zhang;Xiaoping Miao;Wen Tan;Baitang Ning

  • Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

    Chen Wu;Chen Wu;Peter Kraft;Kan Zhai;Jiang Chang

  • Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray.

    Aiping Luo;Jianping Kong;Gengxi Hu;Choong Chin Liew

  • S100 protein family in human cancer.

    Hongyan Chen;Chengshan Xu;Qing'e Jin;Zhihua Liu

  • MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1

    S Yang;Y Li;J Gao;T Zhang

  • The Role of P53 and MDM2 Polymorphisms in the Risk of Esophageal Squamous Cell Carcinoma

    Yuan Hong;Xiaoping Miao;Xuemei Zhang;Fang Ding

  • Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma.

    Tong Tong;Yali Zhong;Jianping Kong;Lijia Dong

  • Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations.

    Jiang Chang;Wenle Tan;Zhiqiang Ling;Ruibin Xi

  • Multifunctional Graphdiyne-Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer.

    Xuantong Zhou;Min You;Fuhui Wang;Zhenzhen Wang

  • Hepatitis B virus (HBV) and hepatitis C virus (HCV) dual infection.

    Zhihua Liu;Jinlin Hou

  • The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy.

    Gui Zhen Wang;Li Zhang;Xin Chun Zhao;Xin Chun Zhao;San Hui Gao

  • Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

    Chen Wu;Zhaoming Wang;Zhaoming Wang;Xin Song;Xin Song;Xiao-Shan Feng

  • Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma.

    Yongping Cui;Hongyan Chen;Ruibin Xi;Heyang Cui;Heyang Cui

  • Gadd45a Expression Induces Bim Dissociation from the Cytoskeleton and Translocation to Mitochondria

    Tong Tong;Junfang Ji;Shunqian Jin;Shunqian Jin;Xianxing Li

Frequent Co-Authors

Qimin Zhan
Qimin Zhan Peking University Stomatological Hospital
Jinlin Hou
Jinlin Hou Southern Medical University
Dongxin Lin
Dongxin Lin Chinese Academy of Sciences
You-Lin Qiao
You-Lin Qiao Peking Union Medical College Hospital
Wen Tan
Wen Tan Peking Union Medical College Hospital
Qianben Wang
Qianben Wang Duke University
Xiaoping Miao
Xiaoping Miao Huazhong University of Science and Technology
Chen Wu
Chen Wu Peking Union Medical College Hospital
Zhaoming Wang
Zhaoming Wang St. Jude Children's Research Hospital
Jiang Chang
Jiang Chang University of Chinese Academy of Sciences

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