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Molecular Biology

D-Index
44
Citations
11096
World Ranking
2899
National Ranking
1384

Overview

Qianben Wang is affiliated with Duke University in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. They have a significant publication record in molecular biology and cancer research, focusing on topics such as prostate cancer treatment and research, genomics and chromatin dynamics, RNA modifications and cancer, and SARS-CoV-2 and COVID-19 research.

Their recent published research includes:

  • RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis (2023, Journal of Clinical Investigation)
  • Shaping Chromatin States in Prostate Cancer by Pioneer Transcription Factors (2020, Cancer Research)
  • A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer (2021, Proceedings of the National Academy of Sciences)
  • Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection (2022, Nature Chemical Biology)
  • Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions (2023, Molecular Cell)

Wang has collaborated frequently with several researchers in the field. Notable coauthors include:

  • Jiaoti Huang
  • Furong Huang
  • William Hankey
  • Zhifen Cui
  • Zhong Chen

Their work has been published predominantly in these venues:

  • Cancer Research (7 publications)
  • Proceedings of the National Academy of Sciences (2 publications)
  • Molecular Cell (2 publications)
  • Nucleic Acids Research (2 publications)
  • Nature Communications (2 publications)

Wang's research covers various subfields connected to their main domains of investigation. These subfields include:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cancer Research
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

The topics most often addressed in Wang's research are:

  • Prostate Cancer Treatment and Research
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Cancer, Lipids, and Metabolism
  • Cancer, Hypoxia, and Metabolism
  • SARS-CoV-2 and COVID-19 Research

Best Publications

  • Genome-wide analysis of estrogen receptor binding sites

    Jason S Carroll;Clifford A Meyer;Jun Song;Wei Li

  • FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

    Mathieu Lupien;Jérôme Eeckhoute;Clifford A. Meyer;Qianben Wang

  • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

    Qianben Wang;Wei Li;Yong Zhang;Xin Yuan

  • A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth

    Qianben Wang;Wei Li;X. Shirley Liu;Jason S. Carroll

  • Nucleosome dynamics define transcriptional enhancers.

    Housheng Hansen He;Clifford A. Meyer;Hyunjin Shin;Shannon T. Bailey

  • Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking

    Qianben Wang;Qianben Wang;Jason S. Carroll;Jason S. Carroll;Myles Brown;Myles Brown

  • Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor suppressor genes

    Kaifu Chen;Kaifu Chen;Kaifu Chen;Zhong Chen;Dayong Wu;Lili Zhang

  • The Role of microRNA-221 and microRNA-222 in Androgen-Independent Prostate Cancer Cell Lines

    Tong Sun;Qianben Wang;Steven Balk;Myles Brown

  • ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer.

    Changmeng Cai;Hongyun Wang;Housheng Hansen He;Sen Chen

  • Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages.

    Xun Lan;Heather Witt;Koichi Katsumura;Zhenqing Ye

  • CaM kinase kinase β-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

    Daniel E. Frigo;Matthew K. Howe;Bryan M. Wittmann;Abigail M. Brunner

  • Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth

    Zhong Chen;Chunpeng Zhang;Dayong Wu;Hongyan Chen

  • Cooperation between Polycomb and androgen receptor during oncogenic transformation

    Jonathan C. Zhao;Jianjun Yu;Christine Runkle;Longtao Wu

  • Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer

    Dayong Wu;Benjamin Sunkel;Zhong Chen;Xiangtao Liu

  • Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13.

    Zhong Chen;Dayong Wu;Jennifer M. Thomas-Ahner;Changxue Lu

  • Specific Structural Motifs Determine TRAP220 Interactions with Nuclear Hormone Receptors

    Yunsheng Ren;Evan Behre;Zhaojun Ren;Jiachang Zhang

  • A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.

    Qianben Wang;Dipali Sharma;Yunsheng Ren;Joseph D. Fondell

  • Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping

    Pei Yin Hsu;Hang Kai Hsu;Gregory A.C. Singer;Pearlly S. Yan

  • Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance.

    Mingjun Bi;Zhao Zhang;Yi Zhou Jiang;Pengya Xue

  • Definition of a FoxA1 Cistrome That Is Crucial for G1 to S-Phase Cell-Cycle Transit in Castration-Resistant Prostate Cancer

    Chunpeng Zhang;Liguo Wang;Dayong Wu;Hongyan Chen

Frequent Co-Authors

Myles Brown
Myles Brown Harvard University
Victor X. Jin
Victor X. Jin Medical College of Wisconsin
Jiaoti Huang
Jiaoti Huang Duke University
Tim H M Huang
Tim H M Huang The University of Texas Health Science Center at San Antonio
Wei Li
Wei Li Harvard University
Jason S. Carroll
Jason S. Carroll University of Cambridge
X. Shirley Liu
X. Shirley Liu Harvard University
Steven K. Clinton
Steven K. Clinton The Ohio State University
Zhihua Liu
Zhihua Liu Peking Union Medical College Hospital
Mathieu Lupien
Mathieu Lupien Princess Margaret Cancer Centre

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