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D-Index & Metrics

Molecular Biology

D-Index
63
Citations
26074
World Ranking
1771
National Ranking
889

Overview

Jindan Yu is affiliated with Emory University in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses a broad range of topics, focusing primarily on prostate cancer treatment and research, as well as cancer metabolism and epigenetic regulation.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of examination cover:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cancer Research
  • Genetics
  • Immunology

The main topics of work are:

  • Prostate Cancer Treatment and Research
  • Cancer, Lipids, and Metabolism
  • Epigenetics and DNA Methylation
  • Protein Degradation and Inhibitors
  • Cancer-related gene regulation
  • Ubiquitin and proteasome pathways
  • Cancer-related molecular mechanisms research

Jindan Yu has published in various scientific journals, with frequent publication venues including:

  • Cancer Research
  • Oncogene
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Translational Pediatrics
  • Nature Genetics

Among recent papers, the following are notable for their focus and publication year:

  • HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer, 2022, Nature Genetics
  • Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer, 2020, Nature Communications
  • Going beyond Polycomb: EZH2 functions in prostate cancer, 2021, Oncogene
  • Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer, 2021, Science Advances
  • The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors, 2022, Cellular and Molecular Life Sciences

Frequent collaborators in research include:

  • Jonathan C. Zhao
  • Xiaodong Lü
  • Galina Gritsina
  • Ka-wing Fong
  • Lourdes Brea

Jindan Yu's work addresses key molecular mechanisms in prostate cancer and related fields, with a focus on epigenetic regulation, protein stability, and cancer metabolism. Their contributions span multiple aspects of cancer biology, including gene regulation, posttranslational modifications, and the ubiquitin-proteasome system.

Best Publications

  • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

    Bin Zhao;Xiaomu Wei;Weiquan Li;Ryan S. Udan;Ryan S. Udan

  • TEAD mediates YAP-dependent gene induction and growth control

    Bin Zhao;Xin Ye;Jindan Yu;Li Li;Li Li

  • Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

    Arun Sreekumar;Laila M. Poisson;Thekkelnaycke M. Rajendiran;Amjad P. Khan

  • Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

    Sooryanarayana Varambally;Qi Cao;Ram Shankar Mani;Sunita Shankar

  • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

    Qianben Wang;Wei Li;Yong Zhang;Xin Yuan

  • Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

    Scott A. Tomlins;Bharathi Laxman;Saravana M. Dhanasekaran;Beth E. Helgeson

  • An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

    Jindan Yu;Jianjun Yu;Ram Shankar Mani;Qi Cao

  • Role of the TMPRSS2-ERG gene fusion in prostate cancer

    Scott A. Tomlins;Bharathi Laxman;Sooryanarayana Varambally;Xuhong Cao

  • Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis.

    Bin Zhao;Li Li;Lloyd Wang;Cun Yu Wang

  • The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

    Ian Lian;Joungmok Kim;Hideki Okazawa;Jiagang Zhao

  • Repression of E-cadherin by the polycomb group protein EZH2 in cancer

    Qi Cao;J. Yu;S. M. Dhanasekaran;J. H. Kim

  • Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.

    J. Chad Brenner;Bushra Ateeq;Yong Li;Anastasia K. Yocum

  • LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer.

    Xingyang Xue;Yeqing Angela Yang;Ali Zhang;Ka-wing Fong

  • Chimeric transcript discovery by paired-end transcriptome sequencing

    Christopher A. Maher;Nallasivam Palanisamy;John C. Brenner;Xuhong Cao

  • Integrative Genomics Analysis Reveals Silencing of β-Adrenergic Signaling by Polycomb in Prostate Cancer

    Jindan Yu;Qi Cao;Rohit Mehra;Bharathi Laxman

  • Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer

    Qi Cao;Ram Shankar Mani;Bushra Ateeq;Saravana M. Dhanasekaran

  • Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator.

    Jung Kim;Yongik Lee;Xiaodong Lu;Bing Song

  • Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

    Jung H. Kim;Saravana M. Dhanasekaran;John R. Prensner;Xuhong Cao

  • A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: Identification of DDX5-ETV4 fusion protein in prostate cancer

    Bo Han;Rohit Mehra;Saravana M. Dhanasekaran;Jindan Yu

  • The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer

    Teresa Ezponda;Relja Popovic;Mrinal Y. Shah;Eva Martinez-Garcia

Frequent Co-Authors

Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Sooryanarayana Varambally
Sooryanarayana Varambally University of Alabama at Birmingham
Xuhong Cao
Xuhong Cao University of Michigan–Ann Arbor
Rohit Mehra
Rohit Mehra University of Michigan–Ann Arbor
Scott A. Tomlins
Scott A. Tomlins University of Michigan–Ann Arbor
Nallasivam Palanisamy
Nallasivam Palanisamy Henry Ford Health System
Saravana M. Dhanasekaran
Saravana M. Dhanasekaran University of Michigan–Ann Arbor
Mark A. Rubin
Mark A. Rubin University of Bern
Christopher G. Maher
Christopher G. Maher University of Sydney
Anand Swaroop
Anand Swaroop National Institutes of Health

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