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Thomas J. Gardella

Thomas J. Gardella

Harvard University
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
11787
World Ranking
10956
National Ranking
4741

Thomas J. Gardella publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Thomas J. Gardella sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 161 publications — 32nd percentile

32% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Thomas J. Gardella D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Thomas J. Gardella sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Thomas J. Gardella is affiliated with Harvard University in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine. The subfields of study in which Gardella is active include Molecular Biology, Oncology, Endocrinology, Diabetes and Metabolism, Radiology, Nuclear Medicine and Imaging, and Genetics.

Gardella's work focuses on various scientific topics, with notable emphasis on Bone Health and Treatments, Receptor Mechanisms and Signaling, Protein Kinase Regulation and GTPase Signaling, Metabolism, Diabetes, and Cancer, Fibroblast Growth Factor Research, Monoclonal and Polyclonal Antibodies Research, and Growth Hormone and Insulin-like Growth Factors.

The scientist has published frequently in a variety of academic journals. The venues with the highest number of Gardella's publications include the Journal of the Endocrine Society, JBMR Plus, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, and the Proceedings of the National Academy of Sciences.

Among recent published papers are:

  • "Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation," 2021, Science Signaling
  • "Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation," 2020, Nature Chemical Biology
  • "Improved GPCR ligands from nanobody tethering," 2020, Nature Communications
  • "Optimization of PTH / PTHrP Hybrid Peptides to Derive a Long-Acting PTH Analog (LA-PTH)," 2020, JBMR Plus
  • "Precise druggability of the PTH type 1 receptor," 2021, Nature Chemical Biology

Gardella's frequent collaborators include Ashok Khatri, Thomas Dean, Harald Jüppner, Samuel H. Gellman, and Jean-Pierre Vilardaga.

Best Publications

  • Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

    Sébastien Ferrandon;Timothy N Feinstein;Marian Castro;Bin Wang

  • A mutant Escherichia coli σ70 subunit of RNA polymerase with altered promoter specificity

    Thomas James Gardella;Henry Moyle;Miriam M. Susskind

  • Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis

    Thomas Gardella;Peter Medveczky;Takeshi Sairenji;Carel Mulder

  • Parathyroid hormone and parathyroid hormone-related peptide, and their receptors

    Robert C. Gensure;Thomas J. Gardella;Harald Jüppner

  • Receptors for PTH and pTHrP: their biological importance and functional properties

    Michael Mannstadt;Harald Jüppner;Thomas J. Gardella

  • Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream Signaling.

    Gary Hattersley;Thomas Dean;Braden A. Corbin;Hila Bahar

  • Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism.

    Andrew Arnold;Susan A. Horst;Thomas J. Gardella;Hisamitsu Baba

  • Full activation of chimeric receptors by hybrids between parathyroid hormone and calcitonin. Evidence for a common pattern of ligand-receptor interaction.

    Clemens Bergwitz;Thomas J. Gardella;Merrilee R. Flannery;John T. Potts

  • Retromer terminates the generation of cAMP by internalized PTH receptors

    Timothy N Feinstein;Vanessa L Wehbi;Juan A Ardura;David S Wheeler

  • Altered Selectivity of Parathyroid Hormone (PTH) and PTH-Related Protein (PTHrP) for Distinct Conformations of the PTH/PTHrP Receptor

    Thomas Dean;Jean-Pierre Vilardaga;John T. Potts;Thomas James Gardella

  • PTH receptor-1 signalling—mechanistic insights and therapeutic prospects

    Ross W. Cheloha;Samuel H. Gellman;Jean-Pierre Vilardaga;Thomas J. Gardella

  • Endosomal generation of cAMP in GPCR signaling

    Jean-Pierre Vilardaga;Frederic G Jean-Alphonse;Thomas J Gardella

  • Structure and dynamics of the active human parathyroid hormone receptor-1.

    L.H. Zhao;S. Ma;I. Sutkeviciute;D.D. Shen

  • Molecular properties of the PTH/PTHrP receptor.

    Thomas J Gardella;Harald Jüppner

  • Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation

    Makoto Okazaki;Sebastien Ferrandon;Jean-Pierre Vilardaga;Mary L. Bouxsein

  • The extracellular amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide receptor determines the binding affinity for carboxyl-terminal fragments of PTH-(1-34).

    H Jüppner;E Schipani;F R Bringhurst;I McClure

  • Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides

    Augen A. Pioszak;Naomi R. Parker;Thomas J. Gardella;H. Eric Xu

  • Converting Parathyroid Hormone-related Peptide (PTHrP) into a Potent PTH-2 Receptor Agonist

    Thomas J. Gardella;Michael D. Luck;Geoff S. Jensen;Ted B. Usdin

  • Amino-terminal modifications of human parathyroid hormone (PTH) selectively alter phospholipase C signaling via the type 1 PTH receptor: implications for design of signal-specific PTH ligands.

    H. Takasu;T. J. Gardella;M. D. Luck;J. T. Potts

  • International Union of Basic and Clinical Pharmacology. XCIII. The Parathyroid Hormone Receptors—Family B G Protein–Coupled Receptors

    Thomas J. Gardella;Jean-Pierre Vilardaga

Frequent Co-Authors

John T. Potts
John T. Potts Harvard University
Harald Jüppner
Harald Jüppner Harvard University
Henry M. Kronenberg
Henry M. Kronenberg Harvard University
Jean-Pierre Vilardaga
Jean-Pierre Vilardaga University of Pittsburgh
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center
Henry T. Keutmann
Henry T. Keutmann Harvard University
Samuel H. Gellman
Samuel H. Gellman University of Wisconsin–Madison
Ernestina Schipani
Ernestina Schipani University of Michigan–Ann Arbor
Gino V. Segre
Gino V. Segre Harvard University
Ruslan I. Sadreyev
Ruslan I. Sadreyev Harvard University

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Best Scientists Citing Thomas J. Gardella

Harald Jüppner

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Publications: 71

Laurence J. Miller

Laurence J. Miller

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Publications: 54

Patrick M. Sexton

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Publications: 50

Michael Chorev

Michael Chorev

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Publications: 40

Denise Wootten

Denise Wootten

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Publications: 35

Jean-Pierre Vilardaga

Jean-Pierre Vilardaga

University of Pittsburgh

Publications: 34

Michael Rosenblatt

Michael Rosenblatt

MSD (United States)

Publications: 34

Henry M. Kronenberg

Henry M. Kronenberg

Harvard University

Publications: 32

Rajesh V. Thakker

Rajesh V. Thakker

University of Oxford

Publications: 32

Louis M. Luttrell

Louis M. Luttrell

Medical University of South Carolina

Publications: 28

Martin J. Lohse

Martin J. Lohse

ISAR Bioscience Institute

Publications: 24

Mark von Zastrow

Mark von Zastrow

University of California, San Francisco

Publications: 24

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Asuka Inoue

Tohoku University

Publications: 24

Dale F. Mierke

Dale F. Mierke

Dartmouth College

Publications: 23

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Michael A. Levine

Children's Hospital of Philadelphia

Publications: 22

Ted B. Usdin

Ted B. Usdin

National Institutes of Health

Publications: 22

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