Denis Riendeau

Denis Riendeau publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Denis Riendeau sits on this spectrum.

Denis Riendeau D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Denis Riendeau sits on this spectrum.

Overview

Best Publications

• Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts

  S Kargman;S Charleson;M Cartwright;J Frank

  703
  Citations

• Etoricoxib (MK-0663): Preclinical Profile and Comparison with Other Agents That Selectively Inhibit Cyclooxygenase-2

  D Riendeau;M D Percival;C Brideau;S Charleson

  654
  Citations

• The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor

  P Prasit;Z Wang;C Brideau;C.-C Chan

  599
  Citations

• The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

  Jacques Yves Gauthier;Nathalie Chauret;Wanda Cromlish;Sylvie Desmarais

  556
  Citations

• Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.

  D Riendeau;M D Percival;S Boyce;C Brideau

  489
  Citations

• Cyclooxygenase-2 Promotes Early Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice

  Michael E. Burleigh;Vladimir R. Babaev;John A. Oates;Raymond C. Harris

  413
  Citations

• Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets.

  D Riendeau;J Guay;P K Weech;F Laliberté

  373
  Citations

• Quinolines as potent 5-lipoxygenase inhibitors: synthesis and biological profile of L-746,530.

  Daniel Dubé;Marc Blouin;Christine Brideau;Chi-Chung Chan

  366
  Citations

• Carrageenan-induced Paw Edema in Rat Elicits a Predominant Prostaglandin E2 (PGE2) Response in the Central Nervous System Associated with the Induction of Microsomal PGE2 Synthase-1

  Jocelyne Guay;Kevin Bateman;Robert Gordon;Joseph Mancini

  359
  Citations

• Cloning, expression, and up-regulation of inducible rat prostaglandin E synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis

  Joseph A. Mancini;Katherine Blood;Jocelyne Guay;Robert Gordon

  343
  Citations

• Microsomal Prostaglandin E Synthase-1 Is a Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production in the Rat Adjuvant-Induced Arthritis Model

  David Claveau;Mirna Sirinyan;Jocelyne Guay;Robert Gordon

  266
  Citations

• Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays

  Denis Riendeau;Stella Charleson;Wanda Cromlish;Joseph A. Mancini

  255
  Citations

• Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase activities.

  Per-Johan Jakobsson;Joseph A. Mancini;Denis Riendeau;Anthony W. Ford-Hutchinson

  237
  Citations

• MF63 {2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)isophthalonitrile}, a selective microsomal prostaglandin E synthase 1 inhibitor, relieves pyresis and pain in preclinical models of inflammation

  Daigen Xu;Steven E. Rowland;Patsy Clark;André Giroux

  213
  Citations

• Lysosomotropism of Basic Cathepsin K Inhibitors Contributes to Increased Cellular Potencies against Off-Target Cathepsins and Reduced Functional Selectivity

  Jean-Pierre Falgueyret;Sylvie Desmarais;Renata Oballa;W Cameron Black

  212
  Citations

• Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886.

  Denis Riendeau;Renee Aspiotis;Diane Ethier;Yves Gareau

  210
  Citations

• A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin

  Marc Ouellet;Denis Riendeau;M. David Percival

  199
  Citations

• Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors

  Bernard Côté;Louise Boulet;Christine Brideau;David Claveau

  197
  Citations

• 2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors

  Richard W Friesen;Christine Brideau;Chi Chung Chan;Stella Charleson

  194
  Citations

• Arginine 120 of Prostaglandin G/H Synthase-1 Is Required for the Inhibition by Nonsteroidal Anti-inflammatory Drugs Containing a Carboxylic Acid Moiety

  Joseph A. Mancini;Denis Riendeau;Jean-Pierre Falgueyret;Philip J. Vickers

  191
  Citations