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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
28185
World Ranking
5470
National Ranking
78

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Olof Rådmark is affiliated with the Karolinska Institute in Sweden. Their research primarily focuses on biochemistry, genetics, and molecular biology, as well as immunology and microbiology.

The scientist's work spans several key topics, including:

  • Immune Cell Function and Interaction
  • Immune Response and Inflammation
  • MicroRNA in disease regulation
  • Immune cells in cancer
  • Estrogen and related hormone effects
  • Reproductive System and Pregnancy
  • Cancer-related molecular mechanisms research

Olof Rådmark has appeared as an author or co-author in multiple publication venues, notably:

  • Biochemical Pharmacology
  • The FASEB Journal
  • Proceedings of the National Academy of Sciences
  • Advanced Science
  • Pharmacology & Therapeutics

Their recent published papers include:

  • Formation of eicosanoids and other oxylipins in human macrophages, 2022, Biochemical Pharmacology
  • Human 5-lipoxygenase regulates transcription by association to euchromatin, 2022, Biochemical Pharmacology
  • Modulation of microRNA processing by 5-lipoxygenase, 2020, The FASEB Journal
  • Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells, 2020, Proceedings of the National Academy of Sciences
  • Coactosin-Like Protein Reduces Prostaglandin D2 Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation, 2025, Advanced Science

Frequent co-authors working alongside Olof Rådmark include:

  • Marius Kreiß
  • Dieter Steinhilber
  • Duran Sürün
  • Ann-Kathrin Häfner
  • Stella Uebbing

Best Publications

  • The nuclear RNase III Drosha initiates microRNA processing

    Yoontae Lee;Chiyoung Ahn;Jin Ju Han;Hyounjeong Choi

  • Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

    Jose Pedro Friedmann Angeli;Manuela Schneider;Bettina Proneth;Yulia Y. Tyurina

  • Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

    Alexander Seiler;Manuela Schneider;Heidi Förster;Stephan Roth

  • Ribonuclease activity and RNA binding of recombinant human Dicer.

    Patrick Provost;David Dishart;Johanne Doucet;David Frendewey

  • Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis

    Rainer Spanbroek;Rolf Gräbner;Katharina Lötzer;Markus Hildner

  • Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence.

    Jan Palmblad;Curt L. Malmsten;Ann-Mari Udén;Olof Rådmark

  • 5-Lipoxygenase: regulation of expression and enzyme activity

    Olof Rådmark;Oliver Werz;Dieter Steinhilber;Bengt Samuelsson

  • 5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease.

    Olof Rådmark;Oliver Werz;Dieter Steinhilber;Bengt Samuelsson

  • Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid.

    Takao Shimizu;Olof Radmark;Bengt Samuelsson

  • Leukotriene A4 hydrolase in human leukocytes. Purification and properties.

    O Rådmark;T Shimizu;H Jörnvall;B Samuelsson

  • Molecular cloning and amino acid sequence of human 5-lipoxygenase.

    Matsumoto T;Funk Cd;Rådmark O;Höög Jo

  • 5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.

    Oliver Werz;Jenny Klemm;Bengt Samuelsson;Olof Rådmark

  • Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

    Julia Esser;Ulf Gehrmann;Fabio Luiz D'Alexandri;Alicia M. Hidalgo-Estévez

  • The N-terminal Domain of 5-Lipoxygenase Binds Calcium and Mediates Calcium Stimulation of Enzyme Activity

    Tove Hammarberg;Patrick Provost;Bengt Persson;Olof Rådmark

  • A novel leukotriene produced by stimulation of leukocytes with formylmethionylleucylphenylalanine.

    W Jubiz;O Rådmark;C Malmsten;G Hansson

  • Bronchoalveolar lavage fluid exosomes contribute to cytokine and leukotriene production in allergic asthma

    P. Torregrosa Paredes;J. Esser;C. Admyre;M. Nord

  • Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes

    Oliver Werz;Eva Bürkert;Bengt Samuelsson;Olof Rådmark

  • Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase.

    Takao Shimizu;Takashi Izumi;Yousuke Seyama;Kenji Tadokoro

  • ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma

    Carlo Pergola;Gabriele Dodt;Antonietta Rossi;Eva Neunhoeffer

  • Leukotriene A: stereochemistry and enzymatic conversion to leukotriene B.

    Olof Rådmark;Curt Malmsten;Bengt Samuelsson;David A. Clark

Frequent Co-Authors

Bengt Samuelsson
Bengt Samuelsson Karolinska Institute
Jesper Z. Haeggström
Jesper Z. Haeggström Karolinska Institute
Hans Jörnvall
Hans Jörnvall Karolinska Institute
Takao Shimizu
Takao Shimizu University of Tokyo
Susanne Gabrielsson
Susanne Gabrielsson Karolinska Institute
Jan Palmblad
Jan Palmblad Karolinska University Hospital
Per-Johan Jakobsson
Per-Johan Jakobsson Karolinska University Hospital
Bengt Persson
Bengt Persson Science for Life Laboratory
Mats Hamberg
Mats Hamberg Karolinska Institute
Lidia Sautebin
Lidia Sautebin University of Naples Federico II

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